supported by the National Key R&D Program of China(2022YFA1103200);the Fundamental Research Funds for the Central Universities(2024ZYGXZR077);National Natural Science Foundation of China(32270866,32300693,32471155,3247086822107045);Guangzhou basic and applied basic research funding(2024A04J6259);The Pearl River Talent Recruitment Program(2023ZT10Y154,2021ZT09Y233,2023QN10Y147);South China University of Technology(D6241240);Talent Program and Basic Research Project of Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences(1103792101,GIBHBRP23-02,GIBHBRP24-01);Cooperation Fund of CHCAMS and SZCH(E010221005,CFA202201006);Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine,Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences(KLRB202201,KLRB202305);partially supported by Science and Technology Planning Project of Guangdong Province,China(2023B1212060050,2023B1212120009)。
Pancreatitis is a common gastrointestinal disorder that causes hospitalization with significant morbidity and mortality.The mechanistic pathophysiology of pancreatitis is complicated,limiting the discovery of pharmaco...
supported by the National Natural Science Foundation of China(32322026,32192400,and 32270859);the National Key R&D Program of China(2021YFA0805000)。
Pancreatic trauma,commonly arising from blunt or penetrating injuries,poses clinical challenges due to its proneness to complications and the difficulty in trauma evaluation(Everson et al.,2023).Most current studies o...
supported by Global-Learning&Academic research institution for Master’s PhD students,Postdocs(G-LAMP)Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(RS-2023-00285390 to Daechan Park);the NRF grant funded by the Ministry of Science and ICT(RS-2024-00341899 to Daechan 2022R1A2C2011122 to Jin-Young Jang);supported by DNA Link,Inc.,and there is no conflict of interest.
Patient-derived xenograft(PDX)models have been used to explore therapeutic opportunities for pancreatic ductal adenocarcinoma(PDAC)[1].Although original tumor characteristics are altered by cancer-stromal interactions...
Objective:Patients with ductal-dependent pulmonary circulation require alternative bloodflow to provide and maintain adequate oxygenation.Modified Blalock-Taussig Shunt(MBTS)has been the standard for providing such a ...
supported by the National Natural Science Foundation of China(82371021,82201142);the Science Foundation of Guangdong Province(2023A1515012336,2023A1515010091,2023A1515030238).
Meibomian gland dysfunction(MGD)manifests through two main clinical presentations,characterized by the meibomian gland(MG)ductal obstruction or acinar dropout.While previous research has predominantly associated MGD p...
The choledochal cyst(CC)can be better termed as biliary tract malformation because of the close association of embryology and etiology in the causation of CC.Contrary to Babbitt's postulation of reflux,damage and dila...
Laboratory Animal Foundation Program,Grant/Award Number:SYDW_KY 2021-14;National Natural Science Foundation of China,Grant/Award Number:32070532 and 32270566;Promotion Plan of the Air Force Medical University,Grant/Award Number:2020SWAQ11;the Ethics Committee of Xijing Hospital of FMMU(ethics approval number:KY20203128-1).
Background:Patients with pancreatic ductal adenocarcinoma(PDAC)who undergo surgical resection and receive effective chemotherapy have the best chance for longterm survival.Unfortunately,because of the heterogeneity of...
Supported by the Soonchunhyang University Research Fund,No.2023-0060.
BACKGROUND Laparoscopic choledocholithotomy for a large impacted common bile duct(CBD)stone is a challenging procedure because of the technical difficulty and the possibility of postoperative complications,even in thi...
supported by the National Key R&D Program of China(2022YFA1104102,2022YFA1104603,2022YFC2304801);the National Natural Science Foundation of China(81830073,82272426);the National Provincial special support program for high-level personnel recruitment(Ten-thousand Talents Program,2018RA4016);Zhejiang Public Welfare Project(LY21H030007,LGF21H200006).
Developing functional ductal organoids(FDOs)is essential for liver regenerative medicine.We aimed to construct FDOs with biliary tree networks in rat decellularized liver scaffolds(DLSs)with primary cholangiocytes iso...
Pancreatic ductal adenocarcinoma(PDAC) is a very common but a highly lethal malignancy due to its biological aggressive behavior. PDAC more commonly affects the head than other parts of the pancreas. As PDAC in the he...