supported by grants from China Postdoctoral Science Foundation(2022M712672);the National Natural Science Foundation of China(U21A20373 and 32070749).
ELP3,the catalytic subunit of the Elongator complex,is an acetyltransferase and associated with tumor progression.However,the detail of ELP3 oncogenic function remains largely unclear.Here,we found that ELP3 stabilize...
supported by the National Natural Science Foundation of China(Grant Nos.81760503 and 81760660);the Applied Basic Research Key Project of Yunnan(Grant Nos.2018FE001(-318)and 2018FE001(-123));the Yunnan Health Science and Technology Plan Projects(Grant No.2016NS207).
Cell migration is a finely tuned biological process that often involves epithelial-mesenchymal transition(EMT).EMT is typically characterized by the upregulation of mesenchymal markers such as Snail1.This process has ...
supported by grants from the National Natural Science Foundation of China(31770156 and 2016YFD0300700);the Innovative Research Funding of FAFU,China(CXZX2018051 and CXZX2018052)。
Autophagy is responsible for maintaining fundamental cellular homeostasis and is,therefore,essential for diverse development processes.This study reported that PoElp3,the putative catalytic subunit of Elongator comple...
Elongator complex has been associated with hyperphosphorylated RNA polymerase II and is known to play critical roles in transcriptional elongation, as well as in tRNA modification and specific mechanism of how exocyto...