EPHEDRA

作品数：39被引量：103H指数：6
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相关作者：查丽杭高天鹏石晓妮陈明凯常国华更多>>
相关机构：新疆托峰药业有限责任公司中国科学院化工冶金研究所中国科学院过程工程研究所兰州城市学院更多>>
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Discovery and characterization of naturally occurring covalent inhibitors of SARS-CoV-2 M^(pro)from the antiviral herb Ephedra
《Chinese Journal of Natural Medicines》2024年第9期797-807,共11页HU Qing ZHANG Yiwen CHEN Pengcheng ZHANG Yani ZHU Guanghao LIU Wei WANG Chaoran ZHENG Shuilian SHEN Nonger WANG Haonan HUANG Ping GE Guangbo 
supported by the National Key Research and Development Program of China(No.2022YFC-3502000);the Basic Public Welfare Research Program of Zhejiang Province(No.LGF22H280012);Zhejiang Provincial TCM Science and Technology Plan Project(Nos.2023ZR064,GZY-ZJ-KJ-24004,2024ZL007 and 2022ZB017);the Medical Science and Technology Project of Zhejiang Province(Nos.2022495401,2021KY040 and2022KY069);Zhejiang Provincial Key Projects in Chinese Medicine(Nos.2020ZZ003 and 2021ZZ001);Shanghai Science and Technology Innovation Action Plans(Nos.21S21900600);Zhejiang Province"Ten Thousand People Plan"Science and Technology Innovation Leading Talents Project(No.2020R52029)。
The Chinese herb Ephedra(also known as Mahuang)has been extensively utilized for the prevention and treatment of coronavirus-induced diseases,including coronavirus disease 2019(COVID-19).However,the specific anti-SARS...
关键词：Main protease EPHEDRA Ephedra non-alkaloid fraction Covalent inhibitors Synergistic effect 
Preparation of Ephedra houttuynia Granule and Its Therapeutic Mechanism of Anti-Mycoplasma gallisepticum Infection Based on Network Pharmacology
《Journal of Northeast Agricultural University(English Edition)》2024年第2期76-85,共10页Zhang Huanqi Han Mingdong Miao Yusong Xu Tianqiao Liang Xin Li Jichang 
the National Natural Science Foundation of China(32273062,31973005)。
The use of Chinese herbal medicines can replace antibiotics that cause drug-resistance problems,which are currently necessary for disease control.In this paper,a traditional Chinese medicine compound named Ephedra hou...
关键词：Mycoplasma galliscepticum therapeutic mechanism network pharmacology Ephedra houttuynia granule granulating process 
Methanolic extract of Ephedra alata inhibits breast cancer cells in vitro and in vivo
《Asian Pacific Journal of Tropical Biomedicine》2024年第4期154-161,共8页Fairouz Sioud Aida Lahmer Mouna Selmi Fadwa Chaabane Leila Chekir-Ghedira 
Objective:To determine the anticancer potential of the methanolic extract from Ephedra alata against breast cancer both in vitro and in vivo.Methods:The effects of the methanolic extract of Ephedra alata on the viabil...
关键词：EPHEDRA Breast cancer Apoptosis ANTIOXIDANT MIGRATION 
Diploid species phylogeny and evolutionary reticulation indicate early radiation of Ephedra in the Tethys coast被引量：1
《Journal of Integrative Plant Biology》2023年第12期2619-2630,共12页Qiong Yu Fu-Sheng Yang Ya-Xing Chen Hui Wu Stefanie M.Ickert-Bond Xiao-Quan Wang 
This study was supported by the Strategic Priority Research Program,CAS(XDA23080000);National Key R&D Program of China(2017YFA0605100);Key Research Program of Frontier Sciences,CAS(QYZDJ-SSW-SMC027).
Reconstructing a robust species phylogeny and disentangling the evolutionary and biogeographic history of the gymnosperm genus Ephedra,which has a large genome and rich polyploids,remain a big challenge.Here we recons...
关键词：ALLOPOLYPLOIDY biogeography EPHEDRA PHYLOGENOMICS phylogeny reticulate evolution 
Phytochemical analysis,mineral composition,Assessment of antioxidant properties and cytotoxic potential of Ephedra alata.subsp.Alenda secondary metabolites
《Food Bioscience》2023年第3期1720-1728,共9页Katia Belazougui Samir Mesrouk Hichem Mohammedi Selma Akcha Lynda Aïnouz Samira Faiza Mecherara-Idjeri 
A study of the phytocomposition of Ephedra alata susbp.alenda Trab is here presented.In the essential oil,mainly predominate oxygenated terpenoids such as thymol,cumal and anethole.A chemical screening revealed a high...
关键词：Ephedra alata susbp.alenda Trab Essential oil POLYPHENOLS Haemolysis activity Acute toxicity Trace element 
Using Network Pharmacology and Molecular Docking Tools to Investigate the Potential Mechanism of Ephedra-Gypsum in the Treatment of Respiratory Diseases
《World Journal of Traditional Chinese Medicine》2023年第2期150-159,共10页Can Huang Ling Yuan Yang Niu Ya-Ting Yang Yi-Fan Yang Yi Nan Hong-Li Dou Joanna Japhet 
supported by Grants from the National Natural Science Foundation of China(grant no.U20A20404);National College Students'Innovation and Entrepreneurship Training Program(202210752014).
Objective:The objective of this study was to investigate the potential mechanisms of ephedra-gypsum in the treatment ofrespiratory diseases(RDs)using network pharmacology and molecular docking techniques.Materials and...
关键词：Ephedra-gypsum mechanistic studies molecular docking network pharmacology respiratory diseases 
Ephedra Herb extract ameliorates adriamycin-induced nephrotic syndrome in rats via the CAMKK2/AMPK/mTOR signaling pathway被引量：2
《Chinese Journal of Natural Medicines》2023年第5期371-382,共12页ZHANG Yuhan ZENG Mengnan LI Benke ZHANG Beibei CAO Bing WU Yuanyuan YE Shan XU Ruiqi ZHENG Xiaoke FENG Weisheng 
the National Key Research and Development Project(Nos.2019YFC1708802 and 2017YFC1702800);Henan province high-level personnel special support“ZhongYuan One Thousand People Pla”,Zhongyuan Leading Talent(No.ZYQR201810080);the Major Science and Technology Projects in Henan Province:Study on the key technology for quality control and the key characteristics of Rehmannia glutinosa,Dioscorea opposita Thunb.and Achyranthes bidentata Blume from Henan Province(No.171100310500).
This study aimed to investigate the effect and mechanisms of Ephedra Herb(EH)extract on adriamycin-induced nephrotic syndrome(NS),providing an experimental basis for the clinical treatment of NS.Hematoxylin and eosin ...
关键词：Ephedra Herb Methylephedrine ADRIAMYCIN Nephrotic syndrome CAMKK2/AMPK/mTOR pathway 
Herbgenomics: Decipher molecular genetics of medicinal plants被引量：1
《The Innovation》2022年第6期17-18,共2页Wei Sun Zhichao Xu Chi Song Shilin Chen 
supported by the Scientific and Technological Innovation Project of the China Academy of Chinese Medical Sciences(C12021A03710).
Medicinal plants synthesize a huge repertoire of specialized compounds as protective metabolites when they are confronted with complex abiotic and biotic conditions.Humans have used medicinal plants to treat ailments ...
关键词：EPHEDRA protective MEDICINAL 
Study on the mechanism of action of Ephedra Herba Decoction against influenza A virus based on network pharmacology
《TMR Modern Herbal Medicine》2022年第2期29-37,共9页Yu-Qiang Lu Hui Ding Zhao-Lin Shi Hai-Bo Lin Guo-Cheng Zhang 
This study was supported by the Discipline Innovation Team Construction Project of the Second Affiliated Hospital of Shaanxi University of Chinese Medicine (2020XKTD-A02).
Objective To predict the main bioactive components and potential mechanisms of Ephedra Herba Decoction(Chinese Pinyin abbreviated as MHT)in treating influenza A virus(IAV)based on network pharmacology.Methods Multiple...
关键词：Ephedra Herba Decoction Influenza A virus Network pharmacology 
Action mechanism of Ephedra in treating allergic rhinitis based on network pharmacology
《Journal of Hainan Medical University》2020年第19期47-51,共5页Xin Wang Zhan-Feng Yan Jing-Jing Yuan Lu-Lu Jiao Si-Ming Liu Peng-Peng Hao Li-Li Liu Qiao-Ping Liu Ya-Jing Zhu 
Young teacher project of Beijing university of traditional Chinese medicine(No.2019-JYB-JS-052);Beijing natural science foundation(No.7194292);National natural science foundation(No.8190151365)
Objective:To study the mechanism of ephedra in treating allergic rhinitis by network pharmacology.Methods:the chemical components and corresponding targets of ephedra were searched and screened by TCMSP database.With"...
关键词：EPHEDRA Network pharmacology Allergic rhinitis 
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