Objective To investigate the effects of total alkaloids in Buxus microphylla leaves(ABML)on isolated rats thoracic aorta rings,and then to explore the possible mechanisms underlying the effects.Methods Thoracic aortas...
Supported by:the Natural Science Foundation of Heilongjiang Province,No ZA2006-07
BACKGROUND: Previous studies have demonstrated that intracellular Ca^2+ ([Ca^2+]) overload, excitotoxicity, free radical injury, and nitric oxide toxicity are involved in mechanisms of neuronal death in the ische...