funded by the Natural Science Research Project of Anhui Educational Committee(2023AH050650);the Research Fund Program of Anhui Medical University(2023xkj176).
Backgrounds:As cancer progresses through various stages of malignancy,metastasis,and drug resistance,the Wnt/-catenin signaling is frequently dysregulated.Despite advancements in medical technology and therapeutic str...
funded by the National Key Research and Development Project,grant number 2021YFE0192100;Natural Science Foundation of Hunan Province,grant numbers 2021JJ30694,2023JJ30529;Innovation and Entrepreneurship Training Program for College Students in Hunan Province,grant number S202210555254;Key Projects of Hunan Provincial Education Department,grant number 21A0285;Natural Science Foundation of Hunan Provincial and Municipal Co-Funding,grant number 2022JJ50029;Key Projects of Shaoyang Science and Technology Bureau,grant number 2021GZ031;Innovation and Entrepreneurship Training Program for College Students of the University of South China,grant numbers D202405212006326156,D202405210948392932,D202405211329047648,D202405221955420827.
One of the most prevalent malignant tumors worldwide,stomach cancer still has a high incidence and fatality rate in China,and the number of young people developing early-onset gastric cancer is steadily increasing.The...
Although Helicobacter pylori(H.pylori)is implicated in the development of most cases of gastric cancer with autoimmune gastritis,cases of gastric cancer have been reported in patients testing negative for H.pylori.Her...
Gastric cancer(GC)represents a significant global health burden due to its high morbidity and mortality.Specific behaviors of GC sub-types,distinct dissem-ination patterns,and associated risk-factors remain poorly und...
This study was approved by the Agrı Training and Research Hospital Scientific Research Ethics Committee(No.E-95531838-050.99-86900);conducted in accordance with the Declaration of Helsinki.
BACKGROUND Gastric cancer is a major global health concern,often diagnosed at advanced stages,leading to poor prognosis.Proximal and distal gastric cancers exhibit distinct clinicopathological features.AIM To investig...
The cytochrome P4503A(CYP3A)gene family’s role in early progression of gastric cancer was comprehensively investigated.Its potential as a therapeutic target was evaluated.Upon literature review,aberrant expression of...
BACKGROUND Multiple primary malignant tumors refer to the occurrence of two or more primary malignant tumors in the same organ or multiple organs or tissues at the same time or successively in the same patient,and can...
supported by the National Natural Science Foundation of China(32171437);the National Key R&D Program of China(2019YFA0802401);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(22KJB310017);Suzhou Science and Technology Development Project(SZM2023006);Gusu Key Health Talent Program of Suzhou(GSWS2022122);the Young Physician Scientists Program(ML42900323);Interdisciplinary Basic Frontier Innovation Program(YXY2302015)at Suzhou Medical College of Soochow University;the National Center for International Research(2017B01012);the Jiangsu Key Laboratory of Neuropsychiatric Diseases(BM2013003);a project funded by the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.
Gastric cancer is a malignant gastrointestinal disease characterized by high morbidity and mortality rates worldwide.The occurrence and progression of gastric cancer are influenced by various factors,including the abn...
supported by the National Natural Science Foundation of China(NSFC:82172748 and 82073377);the Guangdong Basic and Applied Basic Research Foundation(2024B1515020120 and 2023A1515110567);the Medical Scientific Research Foundation of Guangdong Province(A2024171).
HER2-positive gastric cancer has a poor prognosis,with a high incidence of drug resistance and a lack of effective treatments for drug-resistant patients.The exploration of the mechanism of resistance to HER2-targeted...
Supported by Ningxia Key Research and Development Program,No.2023BEG02015;Talent Development Projects of Young Qihuang of National Administration of Traditional Chinese Medicine(2020).
BACKGROUND Lotus plumule and its active components have demonstrated inhibitory effects on gastric cancer(GC).However,the molecular mechanism of lotus plumule against GC remains unclear and requires further investigat...