GASTRIC_CANCER

作品数:2176被引量:12933H指数:44
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相关作者:赵群范立侨李勇檀碧波刘炳亚更多>>
相关机构:上海交通大学医学院附属瑞金医院江苏省人民医院中国医科大学附属第一医院郑州大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer
《Oncology Research》2025年第5期1199-1215,共17页JIA CHEN FEI JIANG KAIYI NIU HAODONG ZHAO LI LI HONGZHU YU 
funded by the Natural Science Research Project of Anhui Educational Committee(2023AH050650);the Research Fund Program of Anhui Medical University(2023xkj176).
Backgrounds:As cancer progresses through various stages of malignancy,metastasis,and drug resistance,the Wnt/-catenin signaling is frequently dysregulated.Despite advancements in medical technology and therapeutic str...
关键词:Gastric Cancer(GC) Signature genes Prognosis Carboxypeptidase Z(CPZ) Adipocyte Enhancer Binding Protein 1(AEBP1) 
Classical biomarkers and non-coding RNAs associated with diagnosis and treatment in gastric cancer
《Oncology Research》2025年第5期1069-1089,共21页JINGDAN QUAN ZIXIN WAN WEI WU XINYUAN CAO JIAYUAN QIU XIAOYE LIU ZHIWEI ZHANG 
funded by the National Key Research and Development Project,grant number 2021YFE0192100;Natural Science Foundation of Hunan Province,grant numbers 2021JJ30694,2023JJ30529;Innovation and Entrepreneurship Training Program for College Students in Hunan Province,grant number S202210555254;Key Projects of Hunan Provincial Education Department,grant number 21A0285;Natural Science Foundation of Hunan Provincial and Municipal Co-Funding,grant number 2022JJ50029;Key Projects of Shaoyang Science and Technology Bureau,grant number 2021GZ031;Innovation and Entrepreneurship Training Program for College Students of the University of South China,grant numbers D202405212006326156,D202405210948392932,D202405211329047648,D202405221955420827.
One of the most prevalent malignant tumors worldwide,stomach cancer still has a high incidence and fatality rate in China,and the number of young people developing early-onset gastric cancer is steadily increasing.The...
关键词:Gastric cancer Biomarkers Immune checkpoint molecules Diagnosis MicroRNA CircRNA LncRNA PIRNA 
Gastric cancer in patients with Helicobacter pylori-negative autoimmune gastritis
《World Journal of Gastrointestinal Oncology》2025年第4期8-16,共9页Hiroshi Kishikawa Jiro Nishida 
Although Helicobacter pylori(H.pylori)is implicated in the development of most cases of gastric cancer with autoimmune gastritis,cases of gastric cancer have been reported in patients testing negative for H.pylori.Her...
关键词:Helicobacter pylori Autoimmune gastritis Gastric cancer Gastrointestinal pathology GASTRIN Atrophic gastritis ENDOSCOPY 
Understanding metastatic patterns in gastric cancer: Insights from lymph node distribution and pathology
《World Journal of Gastrointestinal Oncology》2025年第4期36-41,共6页Chris B Lamprecht Tyler Kashuv Brandon Lucke-Wold 
Gastric cancer(GC)represents a significant global health burden due to its high morbidity and mortality.Specific behaviors of GC sub-types,distinct dissem-ination patterns,and associated risk-factors remain poorly und...
关键词:Gastric cancer Lymph node metastasis patterns Upper vs lower gastric cancer Prognostic factors Survival outcomes 
Importance of hematological and inflammatory markers in the localization of gastric cancer
《World Journal of Gastrointestinal Oncology》2025年第4期93-103,共11页Suleyman Dolu Mehmet B Cengiz Huseyin Dongelli Mustafa Gurbuz Mehmet E Arayici 
This study was approved by the Agrı Training and Research Hospital Scientific Research Ethics Committee(No.E-95531838-050.99-86900);conducted in accordance with the Declaration of Helsinki.
BACKGROUND Gastric cancer is a major global health concern,often diagnosed at advanced stages,leading to poor prognosis.Proximal and distal gastric cancers exhibit distinct clinicopathological features.AIM To investig...
关键词:Gastric cancer Cancer localization Inflammatory markers Distal gastric cancer Proximal gastric cancer Hematological markers 
Cytochrome P4503A gene family in gastric cancer:Unveiling diagnostic biomarkers and therapeutic targets for personalized treatment
《World Journal of Clinical Oncology》2025年第4期31-43,共13页Jun-Kun Zhu Jing Wang 
The cytochrome P4503A(CYP3A)gene family’s role in early progression of gastric cancer was comprehensively investigated.Its potential as a therapeutic target was evaluated.Upon literature review,aberrant expression of...
关键词:Gastric cancer Cytochrome P4503A Early diagnosis Therapeutic target Precision medicine 
Multiple primary tumors patient developed microsatellite stable gastric cancer after cadonilimab treatment for liver cancer:A case report
《World Journal of Clinical Oncology》2025年第4期312-320,共9页Si-Qi Luo Li Dai Yong-Jin Zhou Tong He Fang-Jie Wang Xiang-Ren Jin Qian Wang 
BACKGROUND Multiple primary malignant tumors refer to the occurrence of two or more primary malignant tumors in the same organ or multiple organs or tissues at the same time or successively in the same patient,and can...
关键词:Gastric cancer Liver cancer Multiple primary malignant tumors Cadonilimab Case report 
RNA-binding motif protein RBM39 enhances the proliferation of gastric cancer cells by facilitating an oncogenic splicing switch in MRPL33
《Acta Pharmacologica Sinica》2025年第4期1068-1081,共14页Cheng-piao Lu Jia-bin Li Dong-bao Li Yu-hong Wang Xiao-gang Jiang Jing-jing Ma Guoqiang Xu 
supported by the National Natural Science Foundation of China(32171437);the National Key R&D Program of China(2019YFA0802401);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(22KJB310017);Suzhou Science and Technology Development Project(SZM2023006);Gusu Key Health Talent Program of Suzhou(GSWS2022122);the Young Physician Scientists Program(ML42900323);Interdisciplinary Basic Frontier Innovation Program(YXY2302015)at Suzhou Medical College of Soochow University;the National Center for International Research(2017B01012);the Jiangsu Key Laboratory of Neuropsychiatric Diseases(BM2013003);a project funded by the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.
Gastric cancer is a malignant gastrointestinal disease characterized by high morbidity and mortality rates worldwide.The occurrence and progression of gastric cancer are influenced by various factors,including the abn...
关键词:RBM39 MRPL33 gastric cancer PROLIFERATION alternative splicing 
The novel BCL-2/BCL-XL inhibitor APG-1252-mediated cleavage of GSDME enhances the antitumor efficacy of HER2-targeted therapy in HER2-positive gastric cancer
《Acta Pharmacologica Sinica》2025年第4期1082-1096,共15页Qiu-yun Luo Jing Yang Tian Di Zeng-fei Xia Lin Zhang Wen-tao Pan Shan Shi Li-qiong Yang Jian Sun Miao-zhen Qiu Da-jun Yang 
supported by the National Natural Science Foundation of China(NSFC:82172748 and 82073377);the Guangdong Basic and Applied Basic Research Foundation(2024B1515020120 and 2023A1515110567);the Medical Scientific Research Foundation of Guangdong Province(A2024171).
HER2-positive gastric cancer has a poor prognosis,with a high incidence of drug resistance and a lack of effective treatments for drug-resistant patients.The exploration of the mechanism of resistance to HER2-targeted...
关键词:HER2-positive gastric cancer GSDME PYROPTOSIS APG-1252 
Identification of key hub genes associated with anti-gastric cancer effects of lotus plumule based on machine learning algorithms
《World Journal of Gastrointestinal Oncology》2025年第4期384-415,共32页Fan-Di Meng Shu-Min Jia Yu-Bin Ma Yu-Hua Du Wen-Jing Liu Yi Yang Ling Yuan Yi Nan 
Supported by Ningxia Key Research and Development Program,No.2023BEG02015;Talent Development Projects of Young Qihuang of National Administration of Traditional Chinese Medicine(2020).
BACKGROUND Lotus plumule and its active components have demonstrated inhibitory effects on gastric cancer(GC).However,the molecular mechanism of lotus plumule against GC remains unclear and requires further investigat...
关键词:Gastric cancer Lotus plumule Network pharmacology Weighted gene co-expression network analysis Machine learning 
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