supported by the National Natural Science Foundation of China (32170547)to Hui Zhang;the Program for Professor of Special Appointment (Eastern Scholar)at Shanghai Institutions of Higher Learning (TP2018066)to Hui Zhang;the Natural Science Foundation of Shanghai (21ZR1447100)to Wenjuan Wu.
We have developed a dual base editor,rA&GBE,by fusing adenine and glycosylase base editors.It can induce up to eight types of mutations in T0-generation rice,including single-base conversion,simultaneous multiple-base...
the National Natural Science Foundation of China(No.82271412 to J.H.,82025012 to W.J.C.,U1905210 to W.J.C.).
Adult polyglucosan body disease(APBD)is a rare and highly heterogeneous glycogen storage disorder due to biallelic variants in GBE1.1 Typical APBD presentations include gait abnormalities with polyneuropathy,leukodyst...
supported by National Natural Science Foundation of China(Grant Nos.62101121,62101126,62201397,62201393,62271135);China Postdoctoral Science Foundation(Grant Nos.2021M702501,2022T150486);Major Key Project of Peng Cheng Laboratory(Grant No.PCL 2023AS1-4)。
Terahertz band(THz-band,0.3 to 10 THz)communications are envisioned as a promising candidate for 6G and beyond technology,which can provide data capacity tens or even hundreds of Gbps per physical layer link[1-3].Over...
financially supported by the National Key Research and Development Program of China(2018YFA0901300);the National Natural Science Foundation of China(32171449,81903776);a Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-001);Tianjin Natural Science Foundation(20JCYBJC00310);Youth Innovation Promotion Association CAS(2022177).
Base editor techniques have been developed as a means of precisely converting bases without the need for double-stranded DNA breaks(DSBs)or editing templates.Currently,these techniques can be used for cytosine(C)to th...
financially supported by the National Key Research and Development Program of China (2018YFA0903700);the National Natural Science Foundation of China (31861143019, 31770105, 32001041);a Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project (TSBICIP-KJGG-001);Tianjin Natural Science Foundation (20JCYBJC00310)。
Base editor techniques were developed for precise base conversion without requiring double-stranded DNA breaks(DSBs) or an editing template(Komor et al., 2016;Nishida et al., 2016).
Subjective cognitive decline (SCD) is defined as the presence of self-reported cognitive complaints with unimpaired performance in neuropsychological cognitive tests. SCD has been identified as a precursor of mild cog...