GBE

作品数:118被引量:392H指数:11
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相关领域:医药卫生更多>>
相关作者:张志雄胡敏于蕾妍郁青王成章更多>>
相关机构:青岛农业大学华中农业大学中国林业科学研究院上海中医药大学更多>>
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Development of the A&GBE base editor for efficiently generating abundant genetic variation in rice
《The Crop Journal》2024年第6期1801-1805,共5页Wenhui Zhang Yaqi Xu Jingxuan Cui Yingshuang Xue Lijie Zhang Wenjuan Wu Chong Wang Hui Zhang 
supported by the National Natural Science Foundation of China (32170547)to Hui Zhang;the Program for Professor of Special Appointment (Eastern Scholar)at Shanghai Institutions of Higher Learning (TP2018066)to Hui Zhang;the Natural Science Foundation of Shanghai (21ZR1447100)to Wenjuan Wu.
We have developed a dual base editor,rA&GBE,by fusing adenine and glycosylase base editors.It can induce up to eight types of mutations in T0-generation rice,including single-base conversion,simultaneous multiple-base...
关键词:CRISPR A&GBE Genetic variation RICE 
Clinical and genetic heterogeneity of adult polyglucosan body disease caused by GBE1 biallelic mutations in China
《Genes & Diseases》2024年第5期17-20,共4页Yikun Chen Yan Shi Yuan Gao Yan Hu Linying Zhou Jingmei Hong Shirui Gan Xiang Lin Wanjin Chen Guorong Xu Jin He 
the National Natural Science Foundation of China(No.82271412 to J.H.,82025012 to W.J.C.,U1905210 to W.J.C.).
Adult polyglucosan body disease(APBD)is a rare and highly heterogeneous glycogen storage disorder due to biallelic variants in GBE1.1 Typical APBD presentations include gait abnormalities with polyneuropathy,leukodyst...
关键词:GBE BLADDER diagnosis 
Optical-terahertz-optical seamless integration system for dual-λ400 GbE real-time transmission at 290 GHz and 340 GHz被引量:2
《Science China(Information Sciences)》2023年第11期298-300,共3页Jiao ZHANG Mingzheng LEI Min ZHU Bingchang HUA Yuancheng CAI Yucong ZOU Liang TIAN Yunwu WANG Jinbiao XIAO Yongming HUANG Jianjun YU Xiaohu YOU 
supported by National Natural Science Foundation of China(Grant Nos.62101121,62101126,62201397,62201393,62271135);China Postdoctoral Science Foundation(Grant Nos.2021M702501,2022T150486);Major Key Project of Peng Cheng Laboratory(Grant No.PCL 2023AS1-4)。
Terahertz band(THz-band,0.3 to 10 THz)communications are envisioned as a promising candidate for 6G and beyond technology,which can provide data capacity tens or even hundreds of Gbps per physical layer link[1-3].Over...
关键词:hundreds integration system 
银杏叶提取物对尿毒症患者微炎症状态与血清钙磷及免疫功能的影响
《当代医学》2023年第25期47-50,共4页郑颖慧 钟世琦 陈妮桑 
目的探讨银杏叶提取物(GBE)对尿毒症患者微炎症状态、血清钙磷及免疫功能的影响。方法选取2019年4月至2021年4月定南中医院收治的70例尿毒症患者作为研究对象,按照随机数字表法分为常规组与GBE组,每组35例。常规组采用高通量透析治疗,GB...
关键词:尿毒症 GBE 炎症因子 免疫功能 
Achronix为智能网卡提供400 GbE速度和PCIe Gen 5.0功能
《单片机与嵌入式系统应用》2023年第8期94-94,共1页
高性能FPGA芯片和嵌入式FPGA硅知识产权(eFPGA IP)领域的领导性企业Achronix半导体公司宣布:Achronix网络基础架构代码(ANIC)现已包括400 GbE的连接速度。ANIC是一套灵活的FPGA IP模块,专为提升高性能网络传输速度而进行了优化,可用于Sp...
关键词:连接速度 网络基础架构 网络传输速度 IP模块 FPGA芯片 IP网络 智能网卡 
High-throughput base editing KO screening of cellular factors for enhanced GBE
《Journal of Genetics and Genomics》2023年第8期611-614,共4页Jie Yang Dongdong Zhao Xiagu Zhu Yuanzhao Yang Bo Li Siwei Li Chang-Hao Bi Xue-Li Zhang 
financially supported by the National Key Research and Development Program of China(2018YFA0901300);the National Natural Science Foundation of China(32171449,81903776);a Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-001);Tianjin Natural Science Foundation(20JCYBJC00310);Youth Innovation Promotion Association CAS(2022177).
Base editor techniques have been developed as a means of precisely converting bases without the need for double-stranded DNA breaks(DSBs)or editing templates.Currently,these techniques can be used for cytosine(C)to th...
关键词:GBE BASE CBE 
Sequence motifs and prediction model of GBE editing outcomes based on target library analysis and machine learning
《Journal of Genetics and Genomics》2022年第3期254-257,共4页Bo Li Ya-Qiu Li Dongdong Zhao Jie Yang Yan-He Ma Chang-Hao Bi Xue-Li Zhang 
financially supported by the National Key Research and Development Program of China (2018YFA0903700);the National Natural Science Foundation of China (31861143019, 31770105, 32001041);a Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project (TSBICIP-KJGG-001);Tianjin Natural Science Foundation (20JCYBJC00310)。
Base editor techniques were developed for precise base conversion without requiring double-stranded DNA breaks(DSBs) or an editing template(Komor et al., 2016;Nishida et al., 2016).
关键词:PREDICTION EDITOR 
PLA/DGBEA/PTW熔融共混制备可降解生物薄膜及其性能研究被引量:1
《塑料科技》2020年第12期36-40,共5页蒋文俊 傅小奇 张宁 
2013年度江苏省自然科学基金资助项目(BK20130512);2020年度江苏省产学研合作项目(BY2020456)。
通过构建PLA-增塑剂-增韧剂三元体系,固定增塑剂己二酸二乙二醇单丁醚酯(DGBEA)的质量比为8%,增韧剂甲基乙烯-丙烯酸丁酯-甲基丙烯酸缩水甘油酯(PTW)的质量比从0~12%,探究其力学与光学性能、结晶热力学、撕裂面的形貌和降解性能。结果表...
关键词:聚乳酸 己二酸二乙二醇单丁醚酯 甲基乙烯-丙烯酸丁酯-甲基丙烯酸缩水甘油酯 共混改性 生物降解 
鼻内镜术联合银杏叶提取物对鼻窦炎合并鼻息肉患者嗅觉功能及炎症因子水平的影响被引量:4
《中国中西医结合耳鼻咽喉科杂志》2020年第6期423-426,共4页项俊 冯跃 
目的探讨鼻窦内镜术联合银杏叶提取物(ginkgo biloba extract,GBE)对鼻窦炎合并鼻息肉患者嗅觉功能及炎症因子水平的影响。方法选取2017年6月~2018年6月期间我院耳鼻科收治的98例鼻窦炎合并鼻息肉患者作为研究对象。按随机数字表法分为...
关键词:鼻内镜术 GBE 鼻窦炎合并鼻息肉嗅觉功能 炎症因子 
The Effects of Standardized Ginkgo Biloba Extracts (GBE) on Subjective Cognitive Decline (SCD) in Middle-Aged Adults: A Review被引量:1
《Advances in Aging Research》2020年第3期45-65,共21页Joerg Gruenwald Anne Eckert Reto W. Kressig 
Subjective cognitive decline (SCD) is defined as the presence of self-reported cognitive complaints with unimpaired performance in neuropsychological cognitive tests. SCD has been identified as a precursor of mild cog...
关键词:SUBJECTIVE Cognitive DECLINE (SCD) Memory GINKGO Biloba Standardized Extract(s) (GBE) LI1370 EGB 761 
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