GEMCITABINE

作品数:313被引量:907H指数:11
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相关领域:医药卫生更多>>
相关作者:贾林巴一黄鼎智韩如冰李鸿立更多>>
相关机构:中山大学广州医学院天津医科大学广州市第一人民医院更多>>
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相关基金:国家自然科学基金中国博士后科学基金广东省社会发展领域科技计划项目国家重点基础研究发展计划更多>>
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Discussion on gemcitabine combined with targeted drugs in the treatment of pancreatic cancer
《World Journal of Gastroenterology》2023年第3期579-581,共3页Jun-Hao Huang Wei Guo Zhe Liu 
Pancreatic cancer is a malignant tumor with poor prognosis.The treatment of pancreatic cancer depends on the tumor stage and type,and includes local treatment(surgery,radiotherapy and ablation intervention)and systemi...
关键词:Pancreatic cancer CHEMOTHERAPY Targeted therapy GEMCITABINE DRUG COMBINATION 
Anti-tumour activity and toxicological studies of combination treatment of Orthosiphon stamineus and gemcitabine on pancreatic xenograft model
《World Journal of Gastroenterology》2022年第32期4620-4634,共15页Ashwaq Hamid Salem Yehya Ayappa V Subramaniam Muhammad Asif Gurjeet Kaur Amin M S Abdul Majid Chern Ein Oon 
Supported by the NKEA Research Grant Scheme (NRGS) by the Ministry of Agriculture Malaysia;No. 304/CIPPM/650736/k123
BACKGROUND Pancreatic cancer is the most aggressive cancer type.Gemcitabine is the first line chemo-drug used for pancreatic cancer but exerts a broad spectrum of organ toxicities and adverse effects in patients.AIM T...
关键词:Pancreatic cancer Orthosiphon stamineus C5EOSEW5050ESA GEMCITABINE Complementary medicine 
Effective combinations of anti-cancer and targeted drugs for pancreatic cancer treatment
《World Journal of Gastroenterology》2022年第28期3637-3643,共7页Arata Nishimoto 
Pancreatic cancer is highly aggressive and lethal.Due to the lack of effective methods for detecting the disease at an early stage,pancreatic cancer is frequently diagnosed late.Gemcitabine has been the standard chemo...
关键词:Pancreatic cancer GEMCITABINE Targeted drug Combination therapy 
Role of human nucleoside transporters in pancreatic cancer and chemoresistance
《World Journal of Gastroenterology》2021年第40期6844-6860,共17页Carly Jade Carter Ahmed H Mekkawy David L Morris 
The prognosis of pancreatic cancer is poor with the overall 5-year survival rate of less than 5%changing minimally over the past decades and future projections predicting it developing into the second leading cause of...
关键词:Pancreatic cancer GEMCITABINE Human nucleoside transporters Human equilibrative nucleoside transporters Human concentrative nucleotide transporters MUCINS 
Feasibility and efficacy evaluation of metallic biliary stents eluting gemcitabine and cisplatin for extrahepatic cholangiocarcinoma被引量:9
《World Journal of Gastroenterology》2020年第31期4589-4606,共18页Jing-Bo Xiao Jun-Yong Weng Yang-Yang Hu Gui-Long Deng Xin-Jian Wan 
Supported by the National Natural Science Foundation of China,No.81870452 and No.81470904;Science and Technology Development Funds of Shanghai of China,No.16411952400.
BACKGROUND Effective endoscopic management is fundamental for the treatment of extrahepatic cholangiocarcinoma(ECC).However,current biliary stents that are widely used in clinical practice showed no antitumor effect.D...
关键词:Extrahepatic cholangiocarcinoma Drug-eluting stent Local chemotherapy GEMCITABINE CISPLATIN Biliary obstruction 
Endoscopic ultrasound-guided injective ablative treatment of pancreatic cystic neoplasms被引量:5
《World Journal of Gastroenterology》2020年第23期3213-3224,共12页Chen Du Ning-Li Chai En-Qiang Linghu Hui-Kai Li Xiu-Xue Feng 
With the development of cross-sectional imaging modalities and the increasing attention being paid to physical examinations, the prevalence of pancreatic cystic neoplasms(PCNs) has increased. PCNs comprise a broad dif...
关键词:Endoscopic ultrasound-guided ablation Pancreatic cystic neoplasm Ethanol Paclitaxel LAUROMACROGOL GEMCITABINE 
Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer被引量:7
《World Journal of Gastroenterology》2019年第37期5590-5603,共14页Li Wei Jing-Yun Wen Jie Chen Xiao-Kun Ma Dong-Hao Wu Zhan-Hong Chen Jiang-Long Huang 
BACKGROUND Pancreatic cancer is a major cause of cancer-related death,with a 5-year overall survival rate being below 5%.The main causes of poor prognosis in pancreatic cancer include easy metastasis,high recurrence r...
关键词:ADAM28 DRUG RESISTANCE OVEREXPRESSION POOR prognosis DRUG metabolism GEMCITABINE 
Esophageal metastasis of stem cell-subtype hepatocholangio carcinoma:Rare presentation of a rare tumor被引量:1
《World Journal of Gastroenterology》2018年第7期870-875,共6页Maeva Salimon Nicolas Chapelle Tamara Matysiak-Budnik Jean-Francois Mosnier Eric Frampas Yann Touchefeu 
Hepatocholangiocarcinoma(c HCC-ICC) is a rare primary hepatic tumor defined by the presence of histological features of both hepatocellular carcinoma(HCC) and intrahepatic cholangiocarcinoma(ICC). Its prevalence range...
关键词:Hepatocholangiocarcinoma Stem cellsubtype ESOPHAGEAL METASTASIS CHEMOTHERAPY GEMCITABINE plus platinum-based CHEMOTHERAPY 
Nano albumin bound-paclitaxel in pancreatic cancer: Current evidences and future directions被引量:7
《World Journal of Gastroenterology》2017年第32期5875-5886,共12页Guido Giordano Massimo Pancione Nunzio Olivieri Pietro Parcesepe Marianna Velocci Tania Di Raimo Luigi Coppola Giuseppe Toffoli Mario Rosario D’Andrea 
Pancreatic cancer(PDAC) is an aggressive and chemoresistant disease, representing the fourth cause of cancer related deaths in western countries. Majority of patients have unresectable, locally advanced or metastatic ...
关键词:Nano albumin bound-paclitaxel Pancreatic cancer Metastatic disease GEMCITABINE Folfirinox 
Dilemma of first line regimens in metastatic pancreatic adenocarcinoma被引量:2
《World Journal of Gastroenterology》2016年第46期10124-10130,共7页Marwan Ghosn Tony Ibrahim Tarek Assi Elie El Rassy Hampig Raphael Kourie Joseph Kattan 
Pancreatic cancer is one of the deadliest cancers,ranking fourth among cancer-related deaths. Despite all the major molecular advances and treatment breakthroughs, mainly targeted therapies, the cornerstone treatment ...
关键词:Review Metastatic pancreatic cancer FOLFIRINOX Gemcitabine/nab-paclitaxel Pivotal trials 
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