Alzheimer's disease (AD) is characterized by an imbalance between excitatory and inhibitory brain networks,leading to aberrant homeostatic synaptic plasticity.AD has progressively been recognized as syna ptopathy and ...
supported by the National Basic Research Development Program of China(2011CB504506 and2012CB932502);the National Natural Science Foundation of China(81570915,81371503 and 31170965);the Open Fund from CAS Key Laboratory of Brain Function and Diseases,China(2012-3)
Rebound depolarization (RD) is a response to the offset from hyperpolarization of the neuronal mem- brane potential and is an important mechanism for the synaptic processing of inhibitory signals. In the present stu...
The authors are grateful to the late Vasiliy Gorokhov,the head of the tribal community‘Yukagir’(who passed away in Nov 2012),and to the Yukagir community for allowing us to borrow the specimens for this study in Yakutsk,Russia.The Scientific Research Institute of Applied Ecology of the North of Northeastern Federal University,Yakutsk and Bernard Buigues(Saint-Jean de Lus,France)helped with the logistics and provided funds for the specimens to be transported to Yakutsk in 2012.
The frozen bodies of a young woolly mammoth(Mammuthus primigenius),a wild horse(Equus sp.)and a steppe bison(Bison priscus)were recently found in the northern Yakutia(northeastern Siberia).All specimens have preserved...
the National Natural Science Foundation of China (No 30370454,30325022 and 30530240);the National Key Basic Research Program (No_ 2006CB500702);Program for Changjiang Scholars and Inno-vative Research Team in University;Shanghai Metropolitan Fund for Research and Development (No 04DZ14005 and 04XD14004).
Aim: G protein-coupled inwardly rectifying potassium channels (GIRK) are important for neuronal signaling and membrane excitability. In the present study, we intend to find whether GIRK channels express functionall...