GLYPICAN

作品数:23被引量:58H指数:4
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相关领域:医药卫生生物学更多>>
相关作者:倪润洲江枫肖明兵朱净高静更多>>
相关机构:山东大学南通大学新疆医科大学第五附属医院南昌大学更多>>
相关期刊:《Genes & Diseases》《现代肿瘤医学》《Neural Regeneration Research》《海南医学》更多>>
相关基金:北京市自然科学基金国家自然科学基金南通市科技局社会发展科技计划项目国家重点基础研究发展计划更多>>
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  • 学科=医药卫生—肿瘤x
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FTO-mediated m6A modification alleviates autoimmune uveitis by regulating microglia phenotypes via the GPC4/TLR4/NF-κB signaling axis被引量:1
《Genes & Diseases》2023年第5期2179-2193,共15页Siyuan He Wanqian Li Guoqing Wang Xiaotang Wang Wei Fan Zhi Zhang Na Li Shengping Hou 
supported by the National Natural Science Foundation Project of China(No.82070951,82271078 and 81873678);the Innovative Research Group Project of Chongqing Education Commission(China)(No.CXQT19015);the Natural Science Foundation Project of Chongqing,China(No.cstc2019jcyjmsxmx0120);the Innovation Supporting Plan of Overseas Study of Chongqing,China(No.cx2018010);the Chongqing Education Commission(China)(No.KJQN202000406);the National Key Clinical Specialties Construction Program of China,Chongqing Branch of National Clinical Research Center for Ocular Diseases;the Chongqing Key Laboratory of Ophthalmology(China)(CSTC,No.2008CA5003);Natural Science Foundation Project of Chongqing Medical University(China)(No.W0047).
Uveitis,a vision-threatening inflammatory disease worldwide,is closely related to resident microglia.Retinal microglia are the main immune effector cells with strong plasticity,but their role in uveitis remains unclea...
关键词:Fat mass and obesity-associated protein Glypican 4 MICROGLIA N6-methyladenosine UVEITIS YTH domain Family protein 3 
Glypican-6在胃肠道间质瘤组织中的表达及其通过ERK1/2通路促进细胞的增殖、迁移及侵袭被引量:2
《现代肿瘤医学》2022年第3期382-388,共7页龚庆豪 高平发 顾志相 蔡一亭 
上海市崇明区“可持续发展科技创新行动计划”项目(编号:CKY2020-13)。
目的:探究Glypican-6对胃肠道间质瘤的作用及其可能的作用机制。方法:收集胃肠道间质瘤组织及其癌旁组织27例,RT-PCR和Western blot检测组织中Glypican-6的表达。选取胃肠道间质瘤细胞系GIST-T1进行体外研究。RT-PCR实验检测细胞中Glypi...
关键词:Glypican-6 胃肠道间质瘤 ERK1/2通路 
Glypican-1表达的研究现状与进展被引量:1
《生理科学进展》2020年第2期103-106,共4页张立霞 刘冬青 
Glypican是硫酸类肝素蛋白多糖家族成员之一,至今为止在哺乳动物中发现存在六种Glypican,而在果蝇发生存在二种Glypican。研究发现,Glypican-1的表达与发育密切相关,被认为在调控细胞增殖、形态发生、血管生成及转移方面扮演极为重要的...
关键词:GLYPICAN HSPG WNTS HEDGEHOGS 
磷脂酰肌醇蛋白聚糖在诊断原发性肝癌中的研究进展被引量:3
《西南军医》2019年第5期428-431,共4页张雷 祁峰 龚建平 
重庆市卫计委科研项目资助(编号:No.2017ZBXM070)
由于导致肝癌的各种危险因素的差异巨大,肝癌的早期检测受到了极大地限制。寻找敏感性和特异性俱佳的HCC诊断指标,对于提高患者生存率及生活质量具有重要意义。磷脂酰肌醇蛋白聚糖(Glypican,GPC)是一种硫酸乙酰肝素蛋白多糖,其家族由六...
关键词:原发性肝癌 磷脂酰肌醇蛋白聚糖 GLYPICAN 诊断方法 
Correlation of serum GP73, SOD and GPC3 contents with cell proliferation and angiogenesis in liver cancer lesion
《Journal of Hainan Medical University》2017年第22期74-77,共4页Hua Xin 
Objective: To study the correlation of serum GP73, SOD and GPC3 contents with cell proliferation and angiogenesis in liver cancer lesion. Methods: Patients who were diagnosed with primary liver cancer in Jianghan Oilf...
关键词:Primary liver cancer GOLGI protein 73 Superoxide DISMUTASE GLYPICAN 3 Proliferation ANGIOGENESIS 
Clinicopathological features of alpha-fetoprotein producing early gastric cancer with enteroblastic differentiation被引量:23
《World Journal of Gastroenterology》2016年第36期8203-8210,共8页Kohei Matsumoto Hiroya Ueyama Kenshi Matsumoto Yoichi Akazawa Hiroyuki Komori Tsutomu Takeda Takashi Murakami Daisuke Asaoka Mariko Hojo Natsumi Tomita Akihito Nagahara Yoshiaki Kajiyama Takashi Yao Sumio Watanabe 
AIM To investigate clinicopathological features of early stage gastric cancer with enteroblastic differentiation(GCED).METHODS We retrospectively investigated data on 6 cases of early stage GCED and 186 cases of early...
关键词:Alpha-fetoprotein-producing GASTRIC CANCER GASTRIC CANCER with enteroblastic DIFFERENTIATION Early GASTRIC CANCER GLYPICAN 3 SALL4 
Glypican 3 expression in hepatoblastoma and its diagnostic implication
《China Medical Abstracts(Internal Medicine)》2014年第1期44-44,共1页王凤华 
Objective To explore the expression and diagnostic significance of glypican-3(GPC3)in hepatoblastoma.Methods Five tissue microarray paraffin blocks were constructed to include 54
关键词:DIAGNOSTIC paraffin IMPLICATION TRANSCATHETER NEOPLASTIC blocks staining subtype fetal detectable 
GPC3真核表达载体的构建及其对肝癌细胞功能的影响被引量:1
《广西医科大学学报》2011年第3期348-351,共4页凌永赤 方天敏 刘宁 赵荫农 
广西卫生厅重点研究课题(No.广西卫生厅重200703号)
目的:通过构建GPC3增强型绿色荧光蛋白真核表达载体,研究磷脂酰肌醇蛋白聚糖-3(Glypican-3,GPC3)促细胞增殖效应的影响,探讨GPC3基因对肝癌细胞侵袭和转移能力的影响。方法:应用基因重组技术及限制性内切酶酶切构建并鉴定pEGFP-IRES-N1-...
关键词:GLYPICAN 3 真核表达载体 肝癌细胞 增殖 
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