supported by grants and fellowships from the Departamento de Ciência e Tecnologia(DECIT/MS)do Ministério da Saúde,Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq);Instituto Nacional de Ciência e Tecnologia em Medicina Regenerativa,Fundação de AmparoàPesquisa do Estado do Rio de Janeiro(FAPERJ)(to RMO).
Gangliosides,sialic acid-containing sphingolipids,are major constituents of neuronal membranes.According to the number of sialic acids and the structure of the oligosaccharide chain,gangliosides can be classified as s...
supported by the National Natural Science Foundation of China (Nos. 21907038, 32000904);the Natural Science Foundation of Jiangsu Province (No. BK20200601, China);the National Postdoctoral Program for Innovative Talents of China (No. BX20200153);the Health and Family Planning Commission of Wuxi, China (No. Z202005);the Social Development Key Project of Jiangsu Province (No. BE2019632, China);partly supported by the 111 Project (No. 111-2-06, China);the National First-class Discipline Program of Food Science and Technology (No. JUFSTR20180101, China)。
Tumor-associated carbohydrate antigens(TACAs) are attractive targets for vaccine development. In this context, we described a strategy combining artificial TACA and glycoengineering for cancer vaccine development. A 2...
Glycosphingolipids(gangliosides)have been characterized as important biological molecules with a key role as regulators in many physiological processes on cellular,tissue,organ,and organism levels.The deviations in th...