GRANULOSA

作品数：46被引量：143H指数：5
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相关领域：农业科学生物学更多>>
相关作者：陈秀萍姜勋平陈锋剑刘桂琼丁家桐更多>>
相关机构：中国海洋大学华中农业大学扬州大学桂林冶金地质学院更多>>
相关期刊：《Journal of Animal Science and Biotechnology》《Science China(Life Sciences)》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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hUCMSC-derived extracellular vesicles relieve cisplatin-induced granulosa cell apoptosis in mice by transferring antiapoptotic miRNAs
《Journal of Biomedical Research》2025年第1期36-49,共14页Wenjing Tang Haiyan Yan Xiaojun Chen Yanan Pu Xin Qi Liyang Dong Chuan Su 
Financial support for the current study was provided by the grant from"Blue Engineering"Excellent Young Teacher Foundation in Colleges and Universities of Jiangsu Province(Grant No.KY101R202207 to Xiaojun Chen)。
Premature ovarian insufficiency(POI)caused by chemotherapy is a common complication in female cancer survivors of childbearing age.Traditional methods,including mesenchymal stem cell(MSC)transplant and hormone replace...
关键词：CHEMOTHERAPY fertility preservation extracellular vesicles granulosa cell apoptosis microRNAs 
Insights into left-right asymmetric development of chicken ovary at the single-cell level
《Journal of Genetics and Genomics》2024年第11期1265-1277,共13页Tao Wang Dong Leng Zhongkun Cai Binlong Chen Jing Li Hua Kui Diyan Li Zhuanjian Li 
funded by the Natural Science Foundation of Sichuan Province(2022NSFSC1767);the National Natural Science Foundation of China(32360828)。
Avian ovaries develop asymmetrically apart from prey birds,with only the left ovary growing more towards functional organ.Here,we analyze over 135,000 cells from chick's left and right ovaries at six distinct embryoni...
关键词：CHICKEN OVARY Asymmetric development Left-right asymmetry Single-cell transcriptome Pre-granulosa Cellular crosstalk 
High expression circRALGPS2 in atretic follicle induces chicken granulosa cell apoptosis and autophagy via encoding a new protein被引量：1
《Journal of Animal Science and Biotechnology》2024年第3期971-986,共16页Haorong He Yuanhang Wei Yuqi Chen Xiyu Zhao Xiaoxu Shen Qing Zhu Huadong Yin 
This research was funded by The National Key Research and Development Program of China,grant number 2021YFD1300600;China Agriculture Research System of MOF and MARA,grant number CARS-40;Sichuan Science and Technology Program,grant number 2021YFYZ0007,2021YFYZ0031 and 2022YFYZ0005;National Natural Science Foundation of China Grants,grant number 31972543.
Background The reproductive performance of chickens mainly depends on the development of follicles.Abnor-mal follicle development can lead to decreased reproductive performance and even ovarian disease among chick-ens...
关键词：Apoptosis AUTOPHAGY CHICKEN CircRALGPS2 Follicle atresia PARP1 RNC-seq 
miR‑423 sponged by lncRNA NORHA inhibits granulosa cell apoptosis
《Journal of Animal Science and Biotechnology》2024年第2期632-644,共13页Yuqi Li Zhuofan Zhang Siqi Wang Xing Du Qifa Li 
supported by the National Key R&D Program of China(2022YFD1600903);the National Natural Science Foundation of China(32072693);the College Students’Innovative Entrepreneurial Training Plan Program(202110307028).
Background Atresia and degeneration,a follicular developmental fate that reduces female fertility and is triggered by granulosa cell(GC)apoptosis,have been induced by dozens of miRNAs.Here,we report a miRNA,miR-423,th...
关键词：Granulosa cell apoptosis miR-423 NORHA SMAD7 Sow fertility traits 
Smad8 is involvement in follicular development via the regulation of granulosa cell growth and steroidogenesis in mice
《BIOCELL》2024年第1期139-147,共9页DAOLUN YU DEYONG SHE KAI GE LEI YANG RUINA ZHAN SHAN LU YAFEI CAI 
supported by the High-Level Talent Research Start-Up Funds of West Anhui University(No.WGKQ2021031);Key Project of Natural Science Foundation of Anhui Province of China(No.2108085QC136);Key Project of Quality Engineering in Higher Education Institutions of Anhui Province(No.2020jyxm2128);National College Student Innovation and Entrepreneurship Training Program(No.202110370093);Innovation and Entrepreneurship Training Program for College Students of Anhui Province(No.S202010376114).
Background:SMAD family proteins(SMADs)are crucial transcription factors downstream of transforming growth factor beta(TGF-ß)/SMAD signaling pathways that have been reported to play a pivotal role in mammalian reproduc...
关键词：MOUSE Smad8 RNA interference Granulosa cells Growth and steroidogenesis 
Premature Puberty Revealing an Ovarian Tumor in a Five-Year-Old Girl
《Open Journal of Pediatrics》2023年第2期153-157,共5页Senkaye-Lagom Aimée Kissou Yacouba Traoré Oumar Ganamé Aïda Traoré/Tankoano Mariane Kabré Emile Bandré 
Background: Ovarian tumors in the girl child are sometimes revealed by the development of secondary sexual characteristics. The authors report the case of a five-year-old girl in whom the disease was revealed by early...
关键词：Ovarian Tumor Juvenile Granulosa Tumor Early Puberty Early Diagnosis Surgery 
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells被引量：3
《Animal Nutrition》2022年第4期381-390,共10页Xiaoya Li Huali Chen Zelin Zhang Jiaxin Duan Rongmao Hua Xiaodi Li Li Yang Jianyong Cheng Qingwang Li 
financially supported by Ministry of Agriculture Transgenic Major Projects(2018ZX0801013B);Key Industry Innovation Chain of Shaanxi Province(2018ZDCXL-NY-02-06)。
Zearalenone(ZEA)is widely derived from moldy cereal grain,which has adverse effects on animal reproduction.In particular,pigs are more sensitive to ZEA-induced toxicity than other animals.Isorhamnetin has extensive ph...
关键词：ZEARALENONE ISORHAMNETIN OVARIAN GRANULOSA cell Apoptosis Endoplasmic reticulum STRESS Oxidative STRESS 
Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction被引量：5
《Science China(Life Sciences)》2022年第11期2301-2315,共15页Ping Zhou Feng Deng Zi Yang Canhui Cao Hongcui Zhao Fenting Liu Ke Zhong Lin Fu Tianliu Peng Di Sun Hui Liu Rong Li Yang Yu 
the National Natural Science Foundation of China(82101714,81925013,81971381,81771580,81771650,82071612,and 81571400);China Postdoctoral Science Foundation(2021M690259,2021M702223);the National Key Research and Development Project of China(2016YFC1000601,2018YFC1004101)。
Ginsenoside Rb1 shows a strong antioxidant effect and has potential activation effects on Akt.The aim of the present study was to investigate the protective effect of Rb1 on age-related ovarian granulosa cell injury.O...
关键词：ginsenoside Rb1 oxidative stress aging granulosa cell AKT FOXO1 
miRNA sequencing analysis of healthy and atretic follicles of chickens revealed that miR-30a-5p inhibits granulosa cell death via targeting Beclin1被引量：2
《Journal of Animal Science and Biotechnology》2022年第5期1351-1372,共22页Haorong He Dongmei Li Yongtong Tian Qinyao Wei Felix Kwame Amevor Congjiao Sun Chunlin Yu Chaowu Yang Huarui Du Xiaosong Jiang Menggen Ma Can Cui Zhichao Zhang Kai Tian Yao Zhang Qing Zhu Huadong Yin 
financially supported by Sichuan Science and Technology Program(2021YFYZ0031,2021YFYZ0007);China Agriculture Research System of MOF and MARA(CARS-40).
Background:The egg production performance of chickens is affected by many factors,including genetics,nutrition and environmental conditions.These factors all play a role in egg production by affecting the development ...
关键词：Apoptosis Autophagy BECLIN1 Chicken granulosa cells MiR-30a-5p Oxidative stress RNA-seq Steroid hormone 
Tyrosine phosphatase SHP2 in ovarian granulosa cells balances follicular development by inhibiting PI3K/AKT signaling被引量：5
《Journal of Molecular Cell Biology》2022年第7期23-36,共14页Xiaoli Wei Lanping Zheng Yingpu Tian Haibin Wang Youqiang Su Gensheng Feng Chao Wang Zhongxian Lu 
National Key Research and Development Program of China(2018YFC1003701 and 2017YFC1001402);National Natural Science Foundation of China(31970797 and 31671564).
In mammals,the growth and maturation of oocytes within growing follicles largely depends on ovarian granulosa cells(GCs)in response to gonadotropin stimulation.Many signals have been shown to regulate GC proliferation...
关键词：TYROSINE PHOSPHATASE SHP2 GRANULOSA cell FOLLICULAR development PI3K/AKT SIGNALING 
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