supported by grants from the National Natural Science Foundation of China (No.82072699);the Natural Science Basic Research Program of Shaanxi Province,China (Nos.2023-JC-ZD-54 and 2017JM8165).
Objective:Pancreatic cancer is a highly malignant tumor of the digestive tract with a dismal prognosis.A key challenge of pancreatic cancer is its resistance to chemotherapy.The C-mesenchymal-epithelial transition fac...
supported by the National Natural Science Foundation of China (82202739);Guangdong Basic and Applied Basic Research Foundation Natural Science Fund Project-Youth Promotion Project (2024A1515030260);China Statefunded Postdoctoral Researchers Program (GZC20233265);National Natural Science Foundation of China (81972051)。
Osteoarthritis(OA)is an age-related cartilage-degenerating joint disease.Mitochondrial dysfunction has been reported to promote the development of OA.Poly(ADP-ribose)polymerase family member 12(PARP12)is a key regulat...
supported by the National Natural Science Foundation of China(82072943,China);the National Natural Science Foundation of China(82072929,China).
Poly(ADP-ribose)polymerase 1(PARP1)is a DNA-binding protein that is involved in various biological functions,including DNA damage repair and transcription regulation.It plays a crucial role in cisplatin resistance.Nev...