HELICOBACTER_PYLORI

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Selective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide
《Science China(Life Sciences)》2025年第4期1158-1173,共16页Xiaonan Wang Ning Zhou Xuejiao J.Gao Zijing Zhu Minmin Sun Qian Wang Haolin Cao Xuetong Wu Caiyu Zhou Qingkang Zheng Ye Yuan Yuan Liu Lei Chen Jing Jiang Pengcheng Bu Lizeng Gao 
supported by the National Key R&D Program of China(2019YFA0709200);the National Natural Science Foundation of China(22121003,81930050)。
Alternative treatment for the highly prevalent Helicobacter pylori infection is imperative due to rising antibiotic resistance.We unexpectedly discovered that the anti-H.pylori component in garlic is hydrogen polysulf...
关键词：hydrogen polysulfide G6PDH inactivation Helicobacter pylori polysulfide transformation gastric-adaptive 
Helicobacter pylori infection is linked to metabolic dysfunction and associated steatotic liver disease:A large cross-sectional study
《World Journal of Gastroenterology》2025年第13期79-88,共10页Lin Ye Kai Yan Ze Tian Zhi-Hua Xiao Ru-Yi Xie Zheng-Yuan Xie Li Tao 
Supported by Science and Technology Research Program of Jiangxi Provincial Department of Education,No.GJJ210225;2022 Provincial Health and Wellness Committee Science and Technology Program Projects,No.20221096;Jiangxi Provincial Natural Science Foundation's Young Scientists Fund,No.20242BAB20358.
BACKGROUND Helicobacter pylori(H.pylori),a globally widespread pathogen affecting half of the global population,has been increasingly implicated in metabolic disorders,including obesity,dyslipidemia,and metabolic dysf...
关键词：Helicobacter pylori OBESITY Blood glucose Lipid profile Blood pressure Metabolic dysfunction-associated steatotic liver disease 
Amoxicillin high-dose dual therapy for Helicobacter pylori primary eradication:Proton pump inhibitor and potassium-competitive acid blocker,which’s better?
《World Journal of Gastroenterology》2025年第13期100-115,共16页Xue-Er Yang Sheng-Jun Zhang Yuan Liu Shuo-Yi Yao Su-Xin Zhang Xiao-Ming Liu Lun-Xi Liang Fen Wang 
Supported by the National Natural Science Foundation of China,No.82270594;the National Natural Science Foundation for Youths of China,No.82103151;the Outstanding Youth Foundation of Hunan Province,No.2022JJ20092;the Wisdom Accumulation and Talent Cultivation Project of Third Xiangya Hospital of Central South University,No.YX202103.
BACKGROUND Effective acid suppression significantly enhances the eradication rate of Helicobacter pylori(H.pylori).AIM To assess the efficacy and safety of high-dose dual therapy(HDDT)utilizing various highly potent a...
关键词：Helicobacter pylori High-dose dual therapy ESOMEPRAZOLE Vonoprazan Eradication rate 
Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer:A meta-analysis
《World Journal of Clinical Oncology》2025年第4期280-290,共11页Hong-Chang Yang Cheng-Feng Fu Li-Jun Qiao Gen-He Long Li-Fen Yang Biao Yao 
BACKGROUND Gastric cancer(GC)is one of the most common malignancies worldwide,and Helicobacter pylori(HP)infection is a well-established risk factor for its development.Programmed death-ligand 1(PD-L1)expression is a ...
关键词：Helicobacter pylori Gastric cancer Programmed cell death protein 1/programmed death-ligand 1 Immune checkpoint blockade therapy PATHOGENESIS 
Gastric cancer in patients with Helicobacter pylori-negative autoimmune gastritis
《World Journal of Gastrointestinal Oncology》2025年第4期8-16,共9页Hiroshi Kishikawa Jiro Nishida 
Although Helicobacter pylori(H.pylori)is implicated in the development of most cases of gastric cancer with autoimmune gastritis,cases of gastric cancer have been reported in patients testing negative for H.pylori.Her...
关键词：Helicobacter pylori Autoimmune gastritis Gastric cancer Gastrointestinal pathology GASTRIN Atrophic gastritis ENDOSCOPY 
Copper-Bearing Metal-Organic Framework with Mucus-Penetrating Function for the Multi-Effective Clearance of Mucosal Colonized Helicobacter pylori
《Research》2025年第1期164-180,共17页Chunxi Shu Wei Zhang Yiwei Zhang Yu Li Xinbo Xu Yanan Zhou Yue Zhang Qin Zhong Cong He Yin Zhu Xiaolei Wang 
funded by the National Natural Science Foundation of China(grant no.82170580 to Y.Z.);the Key Research and Development Program of Jiangxi Province(20212BBG73004 to X.W.);the Postdoctoral Fellowship Program of CPSF(GZB20230283 to W.Z.).
Helicobacter pylori colonizes over 50%of people worldwide.Biofilm formation through penetrating gastric mucus and resistance acquired by H.pylori markedly reduces the efficacy of traditional antibiotics.The present tr...
关键词：triple therapy mucus penetrating function penetrating gastric mucus mucosal colonized Helicobacter pylori copper bearing metal organic framework helicobacter pylori multi effective clearance traditional antibioticsthe 
Helicobacter pylori-Induced Angiopoietin-Like 4 Promotes Gastric Bacterial Colonization and Gastritis
《Research》2025年第1期718-738,共21页Rui Xie Nan You Wan-Yan Chen Peng Zhu Pan Wang Yi-Pin Lv Geng-Yu Yue Xiao-Lin Xu Jiang-Bo Wu Jing-Yu Xu Si-Xu Liu Mu-Han Lü Sheng-Qian Yang Ping Cheng Fang-Yuan Mao Yong-Sheng Teng Liu-Sheng Peng Jin-Yu Zhang Ya-Ling Liao Shi-Ming Yang Yong-Liang Zhao Weisan Chen Quan-Ming Zou Yuan Zhuang 
supported by grants of the National Natural Science Foundation of China(82000530,82071744,82070578,81870394,32160208,and 82170628);Outstanding Scientific Youth Fund of Guizhou Province(Qiankehe platform talents 2021-5647,Qiankehe platform talents GCC[2023]040);Key Projects of Guizhou Provincial Basic Research Program(Qiankehe foundation-ZK 2021-major project 004);Collaborative Innovation Center of Chinese Ministry of Education(2020-39);Joint project of Chongqing Health Commission and Science and Technology Bureau(2023MSXM004);Sichuan Science and Technology Program(2022ZYD0071);The General Hospital of Western Theater Command(2021-XZYG-B24).
Helicobacter pylori infection is characterized as progressive processes of bacterial persistence and chronic gastritis with features of infiltration of mononuclear cells more than granulocytes in gastric mucosa.Angiop...
关键词：gastric mucosaangiopoietin helicobacter pylori ANGIOPOIETIN infiltration mononuclear cells more COLONIZATION bacterial persistence chronic gastritis helicobacter pylori infection 
Helicobacter pylori-related serum indicators:Cutting-edge advances to enhance the efficacy of gastric cancer screening
《World Journal of Gastrointestinal Oncology》2025年第3期44-58,共15页Hao-Tian Sun 
Helicobacter pylori(H.pylori)infection induces pathological changes via chronic inflammation and virulence factors,thereby increasing the risk of gastric cancer development.Compared with invasive examination methods,H...
关键词：Gastric cancer screening Helicobacter pylori Serum biomarkers Multiple combined serologic testing Noninvasive diagnostic markers 
Antibiotic resistance of Helicobacter pylori and related risk factors in Hunan Province:A multicenter study
《World Journal of Gastroenterology》2025年第12期62-70,共9页Jie Xie Ming-Lin Zhang Min Guo Jian-Guo Li Yuan Liu Hong-Hui Chen Fen Wang 
Supported by the National Natural Science Foundation of China,No.82270594;the Independent Exploration and Innovation Project of Central South University,No.2024ZZTS0966.
BACKGROUND Antibiotic resistance is a key factor influencing the treatment outcomes of Helicobacter pylori(H.pylori)infection.The antibiotic resistance spectrum of H.pylori varies in different regions.We investigated ...
关键词：Helicobacter pylori Antibiotic resistance Stomach disease Resistance risk MULTICENTER 
Overcoming antibiotic-resistant Helicobacter pylori infection:Current challenges and emerging approaches
《World Journal of Gastroenterology》2025年第10期7-29,共23页Gabriel Reis Rocha Fabian Fellipe Bueno Lemos Luis Guilherme de Oliveira Silva Marcel Silva Luz Gabriel Lima Correa Santos Samuel Luca Rocha Pinheiro Mariana Santos Calmon Fabrício Freire de Melo 
Supported by the Industrial Technological Initiation Scholarship of National Council for Scientific and Technological Development,CNPq,Brazil,No.0932204294929829 and No.7414780530977345;the Scientific Initiation Scholarship Programme(PIBIC)of National Council for Scientific and Technological Development,CNPq,Brazil,No.5763023359532159,No.6472982965854452,and No.7340128440641417;the Scientific Initiation Scholarship Programme(PIBIC)of Bahia State Research Support Foundation,FAPESB,Brazil,No.19.573.301.5418;the PERMANECER Programme of Pro-Rectory of Student Assistance at Federal University of Bahia,No.R8EZ-4V4W-6LQX-5LC8;the CNPq Research Productivity Fellow,No.4357511882624145.
Recent studies have shown a noticeable increase in global Helicobacter pylori(H.pylori)resistance,with clarithromycin resistance surpassing 15%in various areas.However,inadequate epidemiological monitoring,especially ...
关键词：Helicobacter pylori Antibiotic resistance Multidrug resistance HETERORESISTANCE Empirical treatment Antimicrobial susceptibility testing 
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