Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and often fatal overactivation of the immune system. It is characterized by inappropriate and dysregulated activation of natural killer (NK) cells, CD8^(+)cyto...
Objective To explore the value of high-resolution CT (HRCT) visual scores and quantitative analysis in assessing pulmonary Langerhans cell histiocytosis(PLCH) in adults.Methods In total 51 adult patients with PLCH con...
Erdheim-Chester Disease (ECD) is a rare condition and has various differential diagnoses with other forms of histiocytosis, classified as one of non-Langerhans histiocytosis. The diagnosis of this condition remains ch...
supported by a grant from the National Natural Science Foundation of China(No.81770164).
Hemophagocytic lymphohistiocytosis(HLH)is a life-threatening clinical syndrome characterized by aberrantly activated macrophages and cytotoxic T cells,leading to mul-tiple organ failure[1].The main manifestations incl...
Rationale and Objectives: Cystic lung disease may be accurately diagnosed by imaging interpretation of specialist radiologists, without other information. We hypothesized that with minimal training non-specialists cou...
Objective Factors influencing the prognosis of hemophagocytic lymphohistiocytosis(HLH)in adults were analyzed based on multicentric data.Methods Clinical data of 124 adult patients with HLH diagnosed in eight medical ...
This work was supported by the National Natural Science Foundation of China(No.81871633).
To the Editor:Hemophagocytic lymphohistiocytosis(HLH)is a severe or even fatal inflammatory condition.Malignant HLH(M-HLH)is one of the most common types of secondary HLH(sHLH),especially in adults.HLH can occur eithe...
supported by the National Natural Science Foundation of China(No.81871633);Beijing Natural Science Foundation(No.7181003).
To the Editor:A 20-year-old man who developed hemophagocytic lymphohistiocytosis(HLH)was treated with methylprednisolone combined with etoposide(VP-16)for 24 weeks.One month after treatment completion,HLH recurred.The...
Introduction:Langerhans cell histiocytosis(LCH),the most common histiocytic disorder,characterized by the abnormal over production of histiocytes that tend to infiltrate single or multiple organ systems leading to sig...
Background: Autoimmunity has increased significantly, alarmingly secondary to global contraception, abortion, fragmenting germ cells;herewith three types of life thr...