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作品数：225被引量：349H指数：8
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相关机构：广西师范学院吉林大学中国科学院重庆大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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Suberoylanilide hydroxamic acid overcomes erlotinib-acquired resistance via phosphatase and tensin homolog deleted on chromosome 10-mediated apoptosis in non-small cell lung cancer被引量：7
《Chinese Medical Journal》2020年第11期1304-1311,共8页Peng-Fei Wu Wei-Wei Gao Cui-Lan Sun Tai Ma Ji-Qing Hao 
Background::Epidermal growth factor receptor(EGFR)tyrosine kinase inhibitors(TKIs),such as erlotinib and gefitinib,are widely used to treat non-small cell lung cancer(NSCLC).However,acquired resistance is unavoidable,...
关键词：Acquired resistance ERLOTINIB Histone deacetylase Lung cancer SAHA 
Involvement of phosphatase and tensin homolog-induced putative kinase 1–Parkin-mediated mitophagy in septic acute kidney injury被引量：13
《Chinese Medical Journal》2019年第19期2340-2347,共8页Xin-Gui Dai Wei Xu Tao Li Jia-Ying Lu Yang Yang Qiong Li Zhen-Hua Zeng Yu-Hang Ai 
This work was supported by grants from the National Natural Science Foundation of China(Nos.81601708,81671960);the Natural Science Foundation of Hunan Province,China(No.2018JJ2014).
Background:Studies have reported mitophagy activation in renal tubular epithelial cells(RTECs)in acute kidney injury(AKI).Phosphatase and tensin homolog-induced putative kinase 1(PINK1)and E3 ubiquitin-protein ligase ...
关键词：Sepsis Acute kidney injury Autophagy MITOPHAGY PHOSPHATASE and TENSIN homolog-induced putative KINASE 1 E3 ubiquitin-protein ligase Parkin 
A Novel Mutation of Notch homolog protein 2 gene in a Chinese Family with Hajdu-Cheney Syndrome被引量：4
《Chinese Medical Journal》2017年第23期2883-2884,共2页Ruo-Lan Gong Jing Wu Tong-Xin Chen 
This research was supported by a grant from the National Natural Science Foundation of China （No. 81571605）.
Hajdu-Cheney syndrome （HCS） is a rare disorder which is characterized by developmental delay, craniofacial anomalies, congenital heart defects, hearing deficit, polycystic kidneys, and bone abnormalities, including ...
关键词：ACROOSTEOLYSIS Hajdu-Cheney Syndrome Notch homolog protein 2 gene OSTEOPOROSIS 
MiR-106b-5p Inhibits Tumor Necrosis Factor-α-induced Apoptosis by Targeting Phosphatase and Tensin Homolog Deleted on Chromosome 10 in Vascular Endothelial Cells被引量：3
《Chinese Medical Journal》2016年第12期1406-1412,共7页Jing Zhang Su-Fang Li Hong Chen Jun-Xian Song 
This research was funded by the National Natural Science Foundation of China (NSFC)
Background： Apoptosis of endothelial cells （ECs） plays a key role in the development of atherosclerosis and there are also evidence indicated that phosphatase and tensin homolog deleted on chromosome 10 （PTEN） is...
关键词：Apoptosis ATHEROSCLEROSIS MicroRNAs Phosphatase and Tensin Homolog Deleted on Chromosome 10 
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