云南高校图书馆联盟文献共享服务平台- TENSIN

TENSIN: 作品数：25被引量：94H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杜波黄立娟姜德友朱智孙保国更多>>; 相关机构：哈尔滨医科大学附属第二医院黑龙江中医药大学哈尔滨医科大学郑州市中心医院更多>>; 相关期刊：《World Journal of Gastroenterology》《Journal of Clinical & Translational Research》《国际免疫学杂志》《中国脊柱脊髓杂志》更多>>; 相关基金：国家自然科学基金黑龙江省科技攻关计划黑龙江省博士后基金湖北省自然科学基金更多>>

C-terminal tensin-like (CTEN) knockin alleviates cystic kidney defects in Tensin-1 knockout mice: 《Genes & Diseases》2023年第3期643-646,共4页Chun-Lung Chiu Shiao-Ya Hong Ying Tan Yuh-Ru Julie Lee Yi-Ping Shih Clifford GTepper Su Hao Lo; supported in part by The National Institutes of Health,USA(No.DK64111,CA102537,and HL139473).The Genomics Shared Resource is supported by the UC Davis Comprehensive Cancer Center Support Grant awarded by the National Cancer Institute,USA(No.NCI P30CA093373).; Tensin-1(TNS1)is a 220 kD focal adhesion protein that binds to actin filaments,integrin receptors,small GTPases,tyrosine-phosphorylated proteins,and lipids.1 These binding activities enable TNS1 to link the actin cyto...; 关键词：KIDNEY TENSIN thereby

蛋白磷酸酶C1-TEN在急性髓系白血病细胞中的表达及抑制FLT3-ITD对其表达的影响被引量：1: 《暨南大学学报（自然科学与医学版）》2022年第6期595-602,共8页罗满生赖旭旺邓晓玲曾艳梅; 江西省自然科学基金项目(20202BAB206064);江西省卫生健康委员会科技计划项目(20202080);赣州市科技局创新人才计划项目【赣市科发(2020)60号】。; 目的:本研究旨在揭示急性髓系白血病(AML)细胞中具有C1结构域并与TENsin同源的蛋白磷酸酶(C1-TEN)的表达情况,并探讨中间串联重复突变FMS样酪氨酸激酶3(FLT3-ITD)抑制条件下C1-TEN的表达水平。方法:利用酪氨酸激酶抑制剂(TKI)索拉菲尼...; 关键词：急性髓系白血病(AML) FMS样酪氨酸激酶3(FLT3) 中间串联重复突变(ITD) 含有C1结构域并与TENsin同源的蛋白磷酸酶(C1-TEN)

Increased tensin 4 expression is related to the histological type of gastric cancer被引量：2: 《World Journal of Clinical Oncology》2021年第12期1202-1214,共13页Marcin Nizioł Justyna Zińczuk Konrad Zaręba Katarzyna Guzińska-Ustymowicz Anna Pryczynicz; BACKGROUND Gastric cancer(GC)is one of the most common malignant tumors worldwide.Tensin 4(TNS4)is an adhesive protein belonging to the tensin family.This protein is located in focal adhesion sites.The TNS4 gene is co...; 关键词：Gastric cancer Tensin 4 Adhesion proteins IMMUNOHISTOCHEMISTRY

Axon regeneration induced by environmental enrichment-epigenetic mechanisms被引量：1: 《Neural Regeneration Research》2020年第1期10-15,共6页Bor Luen Tang; supported by the National University of Singapore Graduate School for Integrative Sciences and Engineering(to BLT); Environmental enrichment is known to be beneficial for cognitive improvement.In many animal models of neurological disorders and brain injury,EE has also demonstrated neuroprotective benefits in neurodegenerative dise...; 关键词：AXON regeneration CREB-binding protein DNA methylation/demethylation dorsal root GANGLION DRG neurons environmental enrichment epigenetics histone acetylation mechanistic target of rapamycin mTOR PHOSPHATASE and TENSIN HOMOLOGUE PTEN

Diabetic neuropathy research: from mouse models to targets for treatment被引量：3: 《Neural Regeneration Research》2019年第11期1870-1879,共10页Vuong M. Pham Shinji Matsumura Tayo Katano Nobuo Funatsu Seiji Ito; Diabetic neuropathy is one of the most serious complications of diabetes, and its increase shows no sign of stopping. Furthermore, current clinical treatments do not yet approach the best effectiveness. Thus, the deve...; 关键词：brain derived NEUROTROPHIC FACTOR DIABETES extrinsic FACTORS NERVE growth FACTOR NERVE regeneration NEUROTROPHIC FACTORS non-obese type 2 DIABETES phosphatase and TENSIN homolog stem cell streptozotocin

Involvement of phosphatase and tensin homolog-induced putative kinase 1–Parkin-mediated mitophagy in septic acute kidney injury被引量：12: 《Chinese Medical Journal》2019年第19期2340-2347,共8页Xin-Gui Dai Wei Xu Tao Li Jia-Ying Lu Yang Yang Qiong Li Zhen-Hua Zeng Yu-Hang Ai; This work was supported by grants from the National Natural Science Foundation of China(Nos.81601708,81671960);the Natural Science Foundation of Hunan Province,China(No.2018JJ2014).; Background:Studies have reported mitophagy activation in renal tubular epithelial cells(RTECs)in acute kidney injury(AKI).Phosphatase and tensin homolog-induced putative kinase 1(PINK1)and E3 ubiquitin-protein ligase ...; 关键词：Sepsis Acute kidney injury Autophagy MITOPHAGY PHOSPHATASE and TENSIN homolog-induced putative KINASE 1 E3 ubiquitin-protein ligase Parkin

PTEN参与神经干细胞调控及脊髓损伤修复的研究进展被引量：2: 《中国脊柱脊髓杂志》2016年第6期555-558,共4页宋志文余常麟丁亚邹红军刘锦波; 1997年,第10号染色体缺失的磷酸酶与张力蛋白同源物基因（phosphatase and tensin homolog deleted on chromosome 10,PTEN）由国外3个独立的研究小组先后克隆命名,这是目前发现的第一个具有磷酸酶活性的抑癌基因,其编码的蛋白在细胞内...; 关键词：神经干细胞脊髓损伤修复蛋白磷酸酶 TENSIN 信号通路抑癌基因张力蛋白 deleted HOMOLOG 磷酸酶活性

Biomarkers for glioblastoma multiforme: status quo: 《Journal of Clinical & Translational Research》2016年第1期3-10,共8页Nicola Montano Quintino Giorgio D’Alessandris Alessandro Izzo Eduardo Fernandez Roberto Pallini; Background:Glioblastoma(GBM)is the most frequent and most malignant central nervous system(CNS)tumor.GBM shows poor prognosis with a median overall survival of 14.6 months,despite current surgical and adjuvant therapi...; 关键词：glioblastoma MULTIFORME prognosis molecular marker survival O(6)-methylguanine-DNA methyltransferase EPIDERMAL GROWTH FACTOR RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR variant III phosphatase and TENSIN homolog deletion vascular endothelial GROWTH FACTOR

第10号染色体缺失的磷酸酶和张力蛋白的同源基因通过减少上皮-间充质转化来抑制胆管癌细胞QBC939的迁移能力: 《中华实验外科杂志》2015年第11期2629-2631,共3页向丹郑富霖李明提爱军张龙李文岗; 国家自然科学基金资助项目（81272246）;厦门市科技计划资助项目（3502220124049）; 目的探讨第10号染色体缺失的磷酸酶和张力蛋白的同源基因（PTEN）对胆管癌细胞株QBC939迁移能力的抑制作用及其机制.方法取4μg PTEN质粒转染胆管癌细胞株QBC939,转染72 h后,采用Transwell迁移实验和Western blot检测上调PTEN对QBC93...; 关键词：胆管癌第10号染色体缺失的磷酸酶和张力蛋白的同源基因上皮-间充质转化 PHOSPHATASE and TENSIN HOMOLOG deleted on chromosome 10

Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN被引量：7: 《World Journal of Gastroenterology》2013年第48期9307-9317,共11页Qi Xue Kai Sun Hai-Jun Deng Shang-Tong Lei Jing-Qing Dong Guo-Xin Li; Supported by National Natural Science Foundation of China,No.81101896;the National Research Foundation for Doctoral Program of Higher Education of China,No.20124433110010; AIM:To investigate the regulative effect of miRNA(miR)-221 on colorectal carcinoma(CRC)cell radiosensitivity and the underlying mechanisms.METHODS:A human CRC-derived cell line was cultured conventionally and exposed ...; 关键词：COLORECTAL carcinoma MIR-221 PHOSPHATASE and TENSIN HOMOLOG deleted on chromosome 10 RADIOSENSITIVITY

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