云南高校图书馆联盟文献共享服务平台- RADIOSENSITIVITY

RADIOSENSITIVITY: 作品数：157被引量：390H指数：10; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：石小燕胡国清顾祥刘艳王军更多>>; 相关机构：华中科技大学镇江市第一人民医院泸州市人民医院广西医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金湖北省自然科学基金天津市自然科学基金国家高技术研究发展计划更多>>

Snail family transcriptional repressor 1 radiosensitizes esophageal cancer via epithelial-mesenchymal transition signaling: From bioinformatics to integrated study: 《World Journal of Gastrointestinal Oncology》2025年第4期286-299,共14页Xiao-Li Lv Qi-Liang Peng Xin-Peng Wang Zhi-Chao Fu Jian-Ping Cao Jian Wang Li-Li Wang Yang Jiao; Supported by the National Key R&D Program of China,No.2022YFC2503700 and No.2022YFC2503703;the National Health Commission Key Laboratory of Nuclear Technology Medical Transformation(Mianyang Central Hospital),No.2023HYX005.; BACKGROUND Esophageal cancer(ESCA)poses a significant challenge in oncology because of the limited treatment options and poor prognosis.Therefore,enhancing the therapeutic effects of radiotherapy for ESCA and identify...; 关键词：Esophageal cancer RADIOSENSITIVITY Snail family transcriptional repressor 1 BIOINFORMATICS Epithelial-mesenchymal transition

Semen podocarpi extract enhances radiosensitivity in nasopharyngeal carcinoma cells via Raf/MEK/ERK signaling pathway: 《Asian Pacific Journal of Tropical Biomedicine》2025年第2期75-84,共10页Fan-Yan Zeng Zeng-Qiong Huang Yong-Cu Sun Xiao-Dong Zhu; supported by the Project of Administration of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region(grant number GZSY22-69);the Middle/Young aged Teachers’Research Ability Improvement Project of Guangxi Higher Education(grant number 2024KY0120).; Objective:To investigate the chemical components of Semen podocarpi extract(SPE)and its effect on nasopharyngeal carcinoma cells and CNE-2R cells.Methods:Chemical components in SPE were identified by UPLC-MS/MS.CCK-8 ...; 关键词：Podocarpus macrophyllus Nasopharyngeal carcinoma RADIOSENSITIZATION Chemical composition Inumakilactone Podocarpus flavone

Enhancing the radiosensitivity of colorectal cancer cells by reducing spermine synthase through promoting autophagy and DNA damage: 《World Journal of Gastrointestinal Oncology》2024年第12期4716-4727,共12页Yu-Bin Guo Yue-Ming Wu Zhi-Zhao Lin; Supported by National Natural Science Foundation of China,No.82102996;Guangdong Provincial Natural Science Foundation,No.2022A1515010517;Guangzhou Science and Technology Plan Project,No.202201011016;President Foundation of Nanfang Hospital,Southern Medical University,No.2020C038.; BACKGROUND Colorectal cancer(CRC),the third most common cancer worldwide,has increasingly detrimental effects on human health.Radiotherapy resistance diminishes treatment efficacy.Studies suggest that spermine synthas...; 关键词：Spermine synthase Colorectal cancer RADIOSENSITIVITY AUTOPHAGY DNA damage

3D bioprinted breast cancer model reveals stroma-mediated modulation of extracellular matrix and radiosensitivity: 《Bioactive Materials》2024年第12期316-327,共12页Theo Desigaux Leo Comperat Nathalie Dusserre Marie-Laure Stachowicz Malou Lea Jean-William Dupuy Anthony Vial Michael Molinari Jean-Christophe Fricain Francois Paris Hugo Oliveira; the financial support of INSERM(France)and"Fondation ARC pour la recherche sur le cancer".; Deciphering breast cancer treatment resistance remains hindered by the lack of models that can successfully capture the four-dimensional dynamics of the tumor microenvironment.Here,we show that microextrusion bioprint...; 关键词：BIOPRINTING Cancer microenvironment Extracellular matrix

MiR-450b-5p enhances the radiosensitivity of HR^(+) and HER2^(−) breast cancer by targeting CDK6: 《Oncology and Translational Medicine》2024年第4期198-203,共6页Ruxing Wu Hanwang Zhang Xiaoyuan Huang Liang Zhuang; Background:The sensitivity of breast cancer cells to radiation is a key cause of locoregional recurrence after postoperative radiotherapy.Several studies have reported that microRNAs(miRNAs)are involved in the radiose...; 关键词：Breast cancer Cyclin-dependent kinase 6 miR-450b-5p RADIOSENSITIVITY

TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response: 《Current Medical Science》2024年第3期545-553,共9页Shi-gui PANG Xin ZHANG Zhao-xin LI Li-fei HE Feng CHEN Ming-long LIU Ying-ze HUANG Jian-mei MO Kong-lan LUO Juan-juan XIAO Feng ZHU; supported by the Guangxi Zhuang Autonomous Region Program of China(No.Z-C20220797);Guangxi Science and Technology Planning Project of China(No.Guike AD20297047);National Natural Science Foundation of China(No.81902849).; Objective Abnormal expression of T-lymphokine-activated killer cell-originated protein kinase(TOPK)was reported to be closely related to the resistance of prostate cancer to radiotherapy and to targeted drug resistanc...; 关键词：T-lymphokine-activated killer cell-originated protein kinase colorectal cancer DNA damage response RADIOSENSITIVITY

Advances of radiotherapy combined with targeted therapy for nasopharyngeal carcinoma: 《Radiation Medicine and Protection》2023年第4期197-203,共7页Xiaoyan Xu Hengzhao Zhuang Yijun Xu Zhongxu Xing Yang Jiao Lili Wang; supported by the National Natural Science Foundation of China(82073476);the National Key R&D Program of China(2022YFC2503700,2022YFC2503703);Jiangsu Provincial Medical Key Discipline(ZDXK202235);Innovation Research Project of Medical and Industrial Cooperation in Suzhou(SLJ2021005),China.; Nasopharyngeal carcinoma is insidious at onset,prone to lymph node metastasis,and has a high rate of locally advanced disease at initial diagnosis.Radiotherapy combined with chemotherapy is the main treatment for loca...; 关键词：Nasopharyngeal carcinoma RADIOTHERAPY Targeted therapy RADIORESISTANCE RADIOSENSITIVITY ANGIOGENESIS

Ginsenoside Rg5 enhances the radiosensitivity of lung adenocarcinoma via reducing HSP90-CDC37 interaction and promoting client protein degradation被引量：1: 《Journal of Pharmaceutical Analysis》2023年第11期1296-1308,共13页Hansong Bai Jiahua Lyu Xinyu Nie Hao Kuang Long Liang Hongyuan Jia Shijie Zhou Churong Li Tao Li; supported by grants from the Project of Sichuan Science and Technology Department,China(Grant No.:2021YJ0010).; Ginsenoside Rg5 is a rare ginsenoside showing promising tumor-suppressive effects.This study aimed to explore its radio-sensitizing effects and the underlying mechanisms.Human lung adenocarcinoma cell lines A549 and C...; 关键词：Ginsenoside Rg5 Lung adenocarcinoma RADIOTHERAPY HSP90 CDC37

Effects of the PARP inhibitor Niraparib on the radiosensitivity of human lung and cervical cancer cells被引量：1: 《Radiation Medicine and Protection》2023年第2期93-97,共5页Yue Feng Shiyi Pi Yuwei Li Yu Zhang Hongwei Zeng Xiangyu E Yang Zhang Jingping Yu; ObjectiveTo investigate the effect of Niraparib,a clinically approved PARP inhibitor on the radiosensitivity of human lung and cervical cancer cells,and preliminarily explore the underlying mechanism.MethodsThe human ...; 关键词：DNA damage repair PARP inhibitor Radiation therapy RADIOSENSITIVITY TUMOR

Advancements in understanding mechanisms of hepatocellular carcinoma radiosensitivity:A comprehensive review被引量：4: 《Chinese Journal of Cancer Research》2023年第3期266-282,共17页Gaoyuan Yang Huamei Yan Yongchang Tang Feng Yuan Mingbo Cao Yupeng Ren Yuxuan Li Zhiwei He Xiaorui Su Zhicheng Yao Meihai Deng; supported by the Science and Technology Plan Project of Guangzhou(No.202102010171);National Natural Science Foundation Cultivation Project of The Third Affiliated Hospital of Sun Yat-sen University(No.2020GZRPYMS11);Natural Science Foundation of Guangdong Province(No.2018A030313641);CSCO-Roche Joint Cancer Research Fund(No.Y-Roche2019/20041)。; Primary liver cancer is a significant health problem worldwide.Hepatocellular carcinoma(HCC)is the main pathological type of primary liver cancer,accounting for 75%-85%of cases.In recent years,radiotherapy has become ...; 关键词：Hepatocellular carcinoma RADIOSENSITIVITY EPIGENETICS non-coding RNA cell death METABOLISM tumor microenvironment reactive oxygen species NANOPARTICLE

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