supported by the National Natural Science Foundation of China,Nos. 82173806 and U1803281;Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Science,Nos. 2021-I2M-1-030 and 2022-I2M-2-002;Non-Profit Central Research Institute Fund of Chinese Academy of Medical Sciences,No. 2022-JKCS-08 (all to RL)。
Long noncoding RNA and microRNA are regulatory noncoding RNAs that are implicated in Alzheimer's disease, but the role of long noncoding RNA-associated competitive endogenous RNA has not been fully elucidated. The lon...
This editorial examines a recent study that used radiomics based on computed tomography(CT)to predict the expression of the fibroblast-related gene enhancer of zeste homolog 2(EZH2)and its correlation with the surviva...
supported by the National Natural Science Foundation of China,Nos.81670925(to FQC),81870732(to DJZ),81800918(to WL),81900933(to YLS);Department of Science and Technology Key Industry Innovation Chain Social Development Field Fund of Shaanxi Province,No.2021ZDLSF02-12(to FQC);the Natural Science Foundation of Shaanxi Province,No.2019JM-009(to JC).
Studies have shown that phosphatase and tensin homolog deleted on chromosome ten(PTEN)participates in the regulation of cochlear hair cell survival.Bisperoxovanadium protects against neurodegeneration by inhibiting PT...
Background: Protein kinase B (AKT/PKB) family is frequently amplified in ovarian cancer (OC). To the greatest of our knowledge, there is a lack of published reports about the amplification of the genes belonging to th...
supported by Alexander von Humboldt(AvH)foundation,Germany(Ref No:IND 1162665 HFST-P)。
The bacterium Rhodococcus erythropolis MI2 uses 4,4´-dithiodibutyric acid(DTDB)as carbon source to synthesize polythioesters(PTE).The first step for the production of PTE using DTDB is catalyzed by an NADH:flavin oxi...
This study was supported by the National Key Basic Research Program of China,No.2017YFA0104701(to XSG);the National Natural Science Foundation of China,No.31730031(to XSG),81870975(to SLZ);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)(to XSG);the Natural Science Foundation of Jiangsu Province,No.BK20202013(to XSG).
Recovery from injury to the peripheral nervous system is different from that of the central nervous system in that it can lead to gene reprogramming that can induce the expression of a series of regeneration-associate...
funded by the National Natural Science Foundation of China(U1905204);China Agricultural Research System of MOF and MARA(CARS-47);Fujian Science and Technology Department(2021N5008);Institute of Oceanology of Fuzhou(2021F02).
Mammalian TGF-β1 plays a crucial role in maintaining immune tolerance and inhibiting autoimmunity.Although several TGF-β1 homologues have been identified in teleosts,their immunosuppressive functions remain unclear....
The most common digestive system(DS)cancers,including tumors of the gastrointestinal tract(GIT)such as colorectal cancer(CRC),gastric cancer(GC)and esophageal cancer(EC)as well as tumors of DS accessory organs such as...
the Caenorhabditis Genetics Center(CGC,funded by NIH Office of Research Infrastructure Programs P40 OD010440);the National Bioresource Project;supported by funding from the Zhejiang Natural Science Foundation(LR17C110001);the National Natural Science Foundation of China(31871200 and 31371435);the National Key Basic Research Program of China(2015CB150300)to C.C;the National Natural Science Foundation of China(31671522,31972891 and 91754111)to S.X
Mitochondria are the central hub for many metabolic processes,including the citric acid cycle,oxidative phosphorylation,and fatty acid oxidation.Recent studies have identified a new mitochondrial protein family,Fam210...