HYDROXYAPATITE

作品数：515被引量：929H指数：10
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相关作者：周科朝朱剑豪储成林韩啸白晶更多>>
相关机构：四川大学中南大学温州医科大学广州医学院第一附属医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金中国博士后科学基金更多>>
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Biodegradable WE43 Mg alloy/hydroxyapatite interpenetrating phase composites with reduced hydrogen evolution
《Bioactive Materials》2024年第12期519-530,共12页Lenka Drotarova Karel Slamecka Tomas Balint Michaela Remesova Radovan Hudak Jozef Zivcak Marek Schnitzer Ladislav Celko Edgar B.Montufar 
supported by the Ministry of Health of the Czech Republic(NW24-10-00195);the Brno University of Technology projects CEITEC VUT/FCH-J-23-8367 and CEITEC VUT-JL 24-8642;CzechNanoLab Research Infrastructure supported by Ministry of Education,Youth and Sports of the Czech Republic(LM2023051)providing access to some devices used for this study.
Biodegradable magnesium implants offer a solution for bone repair without the need for implant removal.However,concerns persist regarding peri-implant gas accumulation,which has limited their widespread clinical accep...
关键词：MAGNESIUM Biodegradable metal Calcium phosphate cement HYDROXYAPATITE Composite 
Regulating the proinflammatory response to composite biomaterials by targeting immunometabolism
《Bioactive Materials》2024年第10期64-73,共10页Chima V.Maduka Ashley V.Makela Anthony Tundo Evran Ural Katlin B.Stivers Maxwell M.Kuhnert Mohammed Alhaj Ehsanul Hoque Apu Nureddin Ashammakhi Kurt D.Hankenson Ramani Narayan Jennifer H.Elisseeff Christopher H.Contag 
Funding for this work was provided in part by the James and Kathleen Cornelius Endowment at MSU.The Mass Spectrometry core at MSU,especially A.J.Schilmiller and J.O’Keefe,helped to analyze releasates.
Composite biomaterials comprising polylactide(PLA)and hydroxyapatite(HA)are applied in bone,cartilage and dental regenerative medicine,where HA confers osteoconductive properties.However,after surgical implantation,ad...
关键词：HYDROXYAPATITE POLYLACTIDE Immunometabolism INFLAMMATION Regenerative medicine 
Co-delivery of rhBMP-2 and zoledronic acid using calcium sulfate/hydroxyapatite carrier as a bioactive bone substitute to enhance and accelerate spinal fusion
《Bioactive Materials》2024年第6期256-271,共16页Xinggui Tian Corina Vater Deepak Bushan Raina Lisa Findeisen Lucas-Maximilian Matuszewski Magnus Tägil Lars Lidgren Anja Winkler Robert Gottwald Niels Modler Klaus-Dieter Schaser Alexander C.Disch Stefan Zwingenberger 
L.L.thanks the Olav Thon Foundation(Grant Number:21-90)for financial support;D.B.R.thanks Maggie-Stephens Foundation(Grant Number:20202004);Sten K Johnson Foundation(Grant Number:2021-0592);The Crafoord Foundation(2021-0550)for research grants.
Recombinant human bone morphogenetic protein-2(rhBMP-2)has been FDA-approved for lumbar fusion,but supraphysiologic initial burst release due to suboptimal carrier and late excess bone resorption caused by osteoclast ...
关键词：Calcium sulfate/hydroxyapatite Bone morphogenetic protein 2 BISPHOSPHONATE Spinal fusion Bone substitute 
Urchin-like multiscale structured fluorinated hydroxyapatite as versatile filler for caries restoration dental resin composites被引量：2
《Bioactive Materials》2024年第5期477-494,共18页Shuning Zhang Xiao Wang Shi Yin Junjun Wang Hongyan Chen Xinquan Jiang 
the support from the National Natural Science Foundation of China(Grant Nos.82201115,81921002);China Postdoctoral Science Foundation(No.2021M702166);the Innovative Research Team of High-level Local Universities in Shanghai,Oral and Maxillofacial Regeneration and Functional Restoration.
Caries is one of the most prevalent human diseases,resulting from demineralization of tooth hard tissue caused by acids produced from bacteria,and can progress to pulpal inflammation.Filling restoration with dental re...
关键词：Dental resin composites Anti-caries bioactivity Versatile fluorinated hydroxyapatite Micromechanical interlocking Tooth remineralization 
Canine ACL reconstruction with an injectable hydroxyapatite/collagen paste for accelerated healing of tendon-bone interface被引量：8
《Bioactive Materials》2023年第2期1-15,共15页Qingsong Jiang Liren Wang Zhanhong Liu Jinlei Su Yajun Tang Peijie Tan Xiangdong Zhu Kai Zhang Xing Ma Jia Jiang Jinzhong Zhao Hai Lin Xingdong Zhang 
supported by the National Key Research and Development Program of China(2018YFC1106200,2018YFC1106203);the National Natural Science Foundation of China(32071330);the Sichuan Science and Technology Innovation Team(2019JDTD0008);the Key Science and Technology Program of Guangxi Province(AA17204085-2).
Healing of an anterior cruciate ligament(ACL)autologous graft in a bone tunnel occurs through the formation of fibrovascular scar tissue,which is structurally and compositionally inferior to normal fibrocartilaginous ...
关键词：Anterior cruciate ligament reconstruction Tendon-bone healing Injectable paste HYDROXYAPATITE COLLAGEN 
Construction of a magnesium hydroxide/graphene oxide/hydroxyapatite composite coating on Mg-Ca-Zn-Ag alloy to inhibit bacterial infection and promote bone regeneration被引量：5
《Bioactive Materials》2022年第12期354-367,共14页Bo Yuan Hewei Chen Rui Zhao Xuangeng Deng Guo Chen Xiao Yang Zhanwen Xiao Antoniac Aurora Bita Ana Iulia Kai Zhang Xiangdong Zhu Antoniac Vasile Iulian Shen Hai Xingdong Zhang 
Inter-Governmental S&T Cooperation Project Between China and Romania(2018LMNY003);Sichuan Science and Technology Program(2019JDTD0008,2021YFS0020);ChinaPostdoctoral Science Foundation (2021M692316, 2020TQ0218).
The improved corrosion resistance, osteogenic activity, and antibacterial ability are the key factors for promoting the large-scale clinical application of magnesium (Mg)-based implants. In the present study, a novel ...
关键词：Mg alloy Composite coating Corrosion resistance Antibacterial ability Osteogenic activity 
Magnetically responsive nanofibrous ceramic scaffolds for on-demand motion and drug delivery被引量：4
《Bioactive Materials》2022年第9期372-381,共10页Yonggang Zhang Jiaping Li Pamela Habibovic 
supported by the Gravitation Program“Materials Driven Regeneration”,funded by the Netherlands Organization for Scientific Research(NWO)(Grant#024.003.013);JL and PH acknowledge financial support by the NWO,Applied and Engineering Sciences(NWO-AES,Grant#16711).
Smart biomaterials,featuring not only bioactivity,but also dynamic responsiveness to external stimuli,are desired for biomedical applications,such as regenerative medicine,and hold great potential to expand the bounda...
关键词：HYDROXYAPATITE Magnetic RESPONSIVE Drug delivery Cell culture 
Zn/Sr dual ions-collagen co-assembly hydroxyapatite enhances bone regeneration through procedural osteo-immunomodulation and osteogenesis被引量：8
《Bioactive Materials》2022年第4期195-206,共12页Zhenyu Zhong Xiaodan Wu Yifan Wang Mengdie Li Yan Li XuLong Liu Xin Zhang Ziyang Lan Jianglin Wang Yingying Du Shengmin Zhang 
supported by National Key R&D Project(2018YFC1105701)of China;National Natural Science Foundation of China(31870960,81801850);the Fundamental Research Funds for the Central Universities,HUST(2019kfyXMBZ021,2020kfyXJJS115).
The immune microenvironment induced by biomaterials played vital roles in bone regeneration.Hydroxyapatite(HA)and its ion-substituted derivates represent a large class of core inorganic materials for bone tissue engin...
关键词：HYDROXYAPATITE Zinc Strontium Biomimetic co-assembly Osteoimmunomodulation 
Effect of minor amounts of β-calcium pyrophosphate and hydroxyapatite on the physico-chemical properties and osteoclastic resorption of β-tricalcium phosphate cylinders被引量：3
《Bioactive Materials》2022年第4期222-235,共14页B.Le Gars Santoni L.Niggli S.Dolder O.Loeffel G.A.Sblendorio R.Heuberger 
the Swiss National Science Foundation for its funding(Grant no.200021_169027).
β-Tricalcium Phosphate(β-TCP),one of the most used bone graft substitutes,may contain up to 5 wt%foreign phase according to standards.Typical foreign phases includeβ-calcium pyrophosphate(β-CPP)and hydroxyapatite(...
关键词：BIOCERAMICS Calcium phosphate β-Tricalcium phosphate β-Calcium pyrophosphate HYDROXYAPATITE Osteoclastic resorption 
A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration被引量：7
《Bioactive Materials》2022年第3期281-298,共18页Peng Guo Xizhe Liu Penghui Zhang Zhongyuan He Zhen Li Mauro Alini RGeoff Richards Sibylle Grad Martin J.Stoddart Guangqian Zhou Xuenong Zou Danny Chan Wei Tian Dafu Chen Manman Gao Zhiyu Zhou Shaoyu Liu 
This study was supported by the National Key R&D Program of China(Grant no.2017YFC1105000);the National Natural Science Foundation of China(Grant no.81772400,31900583,31430030);the Fundamental Research Funds for the Central Universities(Grant no.19ykzd05);the Natural Science Foundation of Guangzhou City(Grant no.201704030082,201807010031);the Foundation of Shenzhen Committee for Science and Technology Innovation(Grant no.JCYJ20190809142211354,GJHZ20180929160004704);the Sanming Project of Medicine in Shenzhen(Grant no.SZSM201911002);and the Beijing Municipal Health Commission(Grant no.BMHC-2021-X,BMHC-2019-9,BMHC-2018-4,PXM2020_026275_000002).Special thanks are extended to Dr.Cheng Ruijuan for technical support.
The osteogenic microenvironment of bone-repairing materials plays a key role in accelerating bone regeneration but remains incompletely defined,which significantly limits the application of such bioactive materials.He...
关键词：INFLAMMATION bioactive finding 
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