Background Hypoxic pulmonary hypertension (HPH) contributes to the pathogenesis of cardiopulmonary diseases.Several lines of evidence indicate that the Rho A/Rho-kinase pathway play an important role in the progress...
Background Hypoxic-ischemic brain injury (HIBI) after cardiopulmonary resuscitation is one of the most devastating neurological conditions that causing the impaired consciousness. However, there were few studies inv...
This research was supported by grants fi-om the National Natural Science Foundation of China (No. 30901640), New Teacher Foundation of China Science and Technology Development Center of Education Ministry (No. 20090142120068), Natural Science Foundation of Hubei Provincial Government (No. 2008CDB155) and Chenguang Program of Wuhan Science and Technology Bureau (No. 200950431170).
Background Delta-like 4 (DLL4) is an endothelium specific Notch ligand and has been shown to function as a regulating factor during physiological and pathological angiogenesis. It has been reported that the DLL4-Not...
Background Recent research suggests that β2-adrenergic agonists increase alveolar fluid clearance (AFC) under physiologic and pathologic conditions. It is unknown whether β3-adrenergic agonists also increase AFC u...
Background Birth asphyxia may result in multiple organ dysfunction such as lung injury. Inhalation of nebulized nitric oxide precursor can selectively reduce pulmonary hypertension. However, it is unknown whether such...
This study was supported by a research grant from the National Natural Science Foundation of China(No.30370629).
Fractalkine (FKN) is the only known chemokine that fulfils the dual functions of an adhesive molecule and a soluble chemoattractant.1 FKN expression was reported increase in lungs of patients with severe pulmonary a...
This study was sponsored by grants from the National Natural Science Foundation of China(No.30371381);Key Projects Foundation of Department of Science and Technology of Shandong province(No.031050102).
Tumoural hypoxia can influence response to radiotherapy and other treatments, and oxygenation status has proved to be a prognostic indicator of the outcome of radiotherapy.1 Therefore, it is important to assess tumour...
Thestudywassupportedbya grantfromtheNationalNaturalScienceFoundationofChina (No 3 0 3 70 62 3 )
Background Hypoxic pulmonary hypertension (HPH) is initiated by inhibition of O 2 sensitive, voltage gated (Kv) channels in pulmonary arterial smooth muscle cells (PASMCs) The mechanism of hypoxic pulmonary hyp...
Background Studies showed that propentofylline enhances the action of adenosine and protects hippocampal neuronal demage against transient global cerebral ischaemia. Our study was to investigate the effect of propent...