HYPOXIC

作品数:306被引量:941H指数:15
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相关领域:医药卫生更多>>
相关作者:谭双香戴爱国胡瑞成丁艳洁蒋犁更多>>
相关机构:首都医科大学南华大学北京大学第一医院中国医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Atorvastatin attenuates involvement of RhoA/Rho-kinase pathway and NF-κB activation in hypoxic pulmonary hypertensive rats被引量:12
《Chinese Medical Journal》2014年第5期869-872,共4页Zhang Yan Dai Li Wu Shangjie Chen Ping Zhao Shuiping 
Background Hypoxic pulmonary hypertension (HPH) contributes to the pathogenesis of cardiopulmonary diseases.Several lines of evidence indicate that the Rho A/Rho-kinase pathway play an important role in the progress...
关键词:hypoxic pulmonary hypertension ATORVASTATIN Rho A/Rho-kinase NF-ΚB vascular remodeling 
Brain metabolism in patients with vegetative state after post-resuscitated hypoxic-ischemic brain injury: statistical parametric mapping analysis of F-18 fluorodeoxyglucose positron emission tomography被引量:2
《Chinese Medical Journal》2013年第5期888-894,共7页Yong Wook Kim Hyoung Seop Kim Young-Sil An 
Background Hypoxic-ischemic brain injury (HIBI) after cardiopulmonary resuscitation is one of the most devastating neurological conditions that causing the impaired consciousness. However, there were few studies inv...
关键词:hypoxic-ischemic brain injury vegetative state brain metabolism 
Effect of DLL4 siRNA on proliferation, migration and tube formation of choroid-retinal endothelial cells under hypoxic conditions被引量:7
《Chinese Medical Journal》2011年第1期118-126,共9页HE Hua LI Bin ZHANG Hong XIANG Nan LI Gui-gang 
This research was supported by grants fi-om the National Natural Science Foundation of China (No. 30901640), New Teacher Foundation of China Science and Technology Development Center of Education Ministry (No. 20090142120068), Natural Science Foundation of Hubei Provincial Government (No. 2008CDB155) and Chenguang Program of Wuhan Science and Technology Bureau (No. 200950431170).
Background Delta-like 4 (DLL4) is an endothelium specific Notch ligand and has been shown to function as a regulating factor during physiological and pathological angiogenesis. It has been reported that the DLL4-Not...
关键词:DLL4  siRNA choroidal neovascularization choroid-retinal endothelial cells hypoxia 
Effect of β3-adrenergic agonists on alveolar fluid clearance in hypoxic rat lungs被引量:6
《Chinese Medical Journal》2010年第8期1028-1033,共6页LI Nai-jing LI Wei HE Ping GU Xiu LI Sheng-qi 
Background Recent research suggests that β2-adrenergic agonists increase alveolar fluid clearance (AFC) under physiologic and pathologic conditions. It is unknown whether β3-adrenergic agonists also increase AFC u...
关键词:β3-adrenergic agonists alveolar fluid clearance HYPOXIA pulmonary edema 
Effect of inhalation of nebulized NO donor substance on acute hypoxic lung injury in newborn piglets被引量:1
《Chinese Medical Journal》2008年第17期1622-1626,共5页XIA Hong-ping HUANG Guo-ying ZHU Jian-xing SUN Bo 
Background Birth asphyxia may result in multiple organ dysfunction such as lung injury. Inhalation of nebulized nitric oxide precursor can selectively reduce pulmonary hypertension. However, it is unknown whether such...
关键词:hypoxia NEWBORN nitric oxide donor NITROGLYCERINE sodium nitroprusside 
Effect of breviscapine on fractalkine expression in chronic hypoxic rats被引量:3
《Chinese Medical Journal》2006年第17期1465-1468,共4页CHEN Xiao-ju CHENG De-yun YANG Li XIA Xiu-qiong GUAN Jian 
This study was supported by a research grant from the National Natural Science Foundation of China(No.30370629).
Fractalkine (FKN) is the only known chemokine that fulfils the dual functions of an adhesive molecule and a soluble chemoattractant.1 FKN expression was reported increase in lungs of patients with severe pulmonary a...
关键词:HYPOXIA pulmonary hypertension FRACTALKINE BREVISCAPINE 
Hypoxic imaging with ^(99m)Tc-HL91 single photon emission computed tomography in advanced nonsmall cell lung cancer被引量:6
《Chinese Medical Journal》2006年第17期1477-1480,共4页LI Ling YU Jin-ming XING Li-gang YANG Guo-ren SUN Xin-dong XU Jin ZHU Hui YUE Jin-bo 
This study was sponsored by grants from the National Natural Science Foundation of China(No.30371381);Key Projects Foundation of Department of Science and Technology of Shandong province(No.031050102).
Tumoural hypoxia can influence response to radiotherapy and other treatments, and oxygenation status has proved to be a prognostic indicator of the outcome of radiotherapy.1 Therefore, it is important to assess tumour...
关键词:lung neoplasm RADIOTHERAPY HYPOXIA 
Chronic mountain sickness on the Qinghai-Tibetan plateau被引量:49
《Chinese Medical Journal》2005年第2期161-168,共8页WUTian-yi 
关键词:chronic mountain sickness hypoxic ventilation POLYCYTHEMIA pulmonary hypertension 
Effect of mitochondrial K_(ATP) channel on voltage gated K^+ channel in 24 hour-hypoxic human pulmonary artery smooth muscle cells被引量:13
《Chinese Medical Journal》2005年第1期12-19,共8页WANGTao ZHANGZhen-xiang XUYong-jian 
Thestudywassupportedbya grantfromtheNationalNaturalScienceFoundationofChina (No 3 0 3 70 62 3 )
Background Hypoxic pulmonary hypertension (HPH) is initiated by inhibition of O 2 sensitive, voltage gated (Kv) channels in pulmonary arterial smooth muscle cells (PASMCs) The mechanism of hypoxic pulmonary hyp...
关键词:pulmonary arterial smooth muscle cell · anoxia · membrane potentials · mitochondrial membrane · potassium channel 
Effect of propentofylline on hypoxic-ischaemic brain damage in newborn rat
《Chinese Medical Journal》2004年第8期1190-1194,共5页夏晓艳 鲛岛浩 大田 Arturo 夏义欣 池ノ上克 年森清隆 黄醒华 
Background Studies showed that propentofylline enhances the action of adenosine and protects hippocampal neuronal demage against transient global cerebral ischaemia. Our study was to investigate the effect of propent...
关键词:hypoxia-ischaemia · brain damage · neonatal rat · propentofylline 
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