云南高校图书馆联盟文献共享服务平台- BREVISCAPINE

BREVISCAPINE: 作品数：13被引量：84H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：陈小夏何冰黄照昌蔡佳黄建明更多>>; 相关机构：广东药学院昆明制药集团股份有限公司复旦大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金国家杰出青年科学基金更多>>

Breviscapine reduces neuronal injury caused by traumatic brain injury insult:partly associated with suppression of interleukin-6 expression被引量：17: 《Neural Regeneration Research》2017年第1期90-95,共6页Ling Jiang Yue Hu Xiang He Qiang Lv Ting-hua Wang Qing-jie Xia; Breviscapine,extracted from the herb Erigeron breviscapus,is widely used for the treatment of cardiovascular diseases,cerebral infarct,and stroke,but its mechanism of action remains unclear.This study established a ra...; 关键词：nerve regeneration breviscapine traumatic brain injury neuroprotective effect interleukin-6 neural regeneration

Therapeutic effect and mechanism of breviscapine on cisplatin-induced nephrotoxicity in mice被引量：6: 《Asian Pacific Journal of Tropical Medicine》2015年第10期853-857,共5页Xiao-Yu Lou Jing-Liang Cheng Bo Zhang; supported by the National Natural Science Foundation of China(No.81401428); Objective:To observe the protective effect of breviscapineon mice with cisplatin-induced nephrotoxicity.Methods:Mice were given a single injection of cisplalin(8 mg/kg,up.);then,breviscapine was given to mice at 25 mg...; 关键词：CISPLATIN RENAL INJURY BREVISCAPINE Protective eff

Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine被引量：6: 《Acta Pharmacologica Sinica》2013年第8期1108-1115,共8页Mei LI Yong ZHENG Feng-ying SHAN Jing ZHOU Tao GONG Zhi-rong ZHANG; Aim： Breviscapine isolated from the Chinese herb Erigeron breviscapus （Vant） Hand-Mazz is widely used to treat cardiovascular and cerebrovascular diseases. The aim of this study was to improve the pharmacokinetic p...; 关键词：BREVISCAPINE OCTADECYLAMINE ionic complex nanostructured lipid carriers sustained release PHARMACOKINETICS

Breviscapine inhibits high glucose-induced proliferation and migration of cultured vascular smooth muscle cells of rats via suppressing the ERK1/2 MAPK signaling pathway被引量：16: 《Acta Pharmacologica Sinica》2012年第5期606-614,共9页Meng HE Zhi-min XUE Juan LI Bin-quan ZHOU; Aim： To investigate the influences of breviscapine, a flavonoid extracted from Erigeron breviscapus, on the proliferation and migration of vascular smooth muscle cells （VSMCs） cultured in a high glucose medium and ...; 关键词：BREVISCAPINE vascular smooth muscle cells cell proliferation cell migration protein kinase C MAP kinase

Breviscapine attenuates acute pancreatitis by inhibiting expression of PKCα and NF-κB in pancreas被引量：11: 《World Journal of Gastroenterology》2011年第14期1825-1830,共6页Hong Zhang Cui-Zhu Cai Xiao-Qin Zhang Tao Li Xiao- Yun Jia Bao-Lan Li Liang Song Xiao-Jun Ma; Supported by Funds of Natural Science of Shaanxi Education, No.05JK176;Natural Science of Shaanxi Province, No.2010JM4023;Natural Science of Xianyang City, No. 2010K14-02(6); AIM:To study the effect of breviscapine (Bre) on activity of protein kinase Cα (PKCα) and nuclear factor (NF)-κB in pancreas,and the mechanism of Bre attenuating acute pancreatitis (AP). METHODS:One hundred and eig...; 关键词：BREVISCAPINE Acute pancreatitis Protein kinase Cα Nuclear factor-κB RAT

Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway被引量：13: 《Acta Pharmacologica Sinica》2009年第8期1081-1091,共11页Min WANG Wen-bin ZHANG Jun-hui ZHU Guo-sheng FU Bin-quan ZHOU; Aim： To investigate the influence of breviscapine on high glucose-induced hypertrophy of cardiomyocytes and the relevant mechanism in vitro and in vivo. Methods： Cultured neonatal cardiomyocytes were divided into i...; 关键词：diabetic cardiomyopathy protein kinase C CARDIOMEGALY BREVISCAPINE

Breviscapine alleviates hepatic injury and inhibits PKC-mRNA and its protein expression in brain-dead BA-Ma mini pigs被引量：3: 《Hepatobiliary & Pancreatic Diseases International》2007年第6期604-609,共6页Zhang, Shui-Jun Song, Yan Zhai, Wen-Long Shi, Ji-Hua Feng, Liu-Shun Zhao, Yong-Fu Chen, Shi; This study was supported by a grant from the Distinguished Innovation of Henan Province (0421002500).; BACKGROUND: Brain-dead donors are the main sources for organ transplantation, but many studies show that brain-death affects the organ's function after transplantation. This study was undertaken to investigate liver i...; 关键词：BREVISCAPINE BA-Ma mini pigs brain-death protein kinase C

The potential therapeutic effects of baicalein and breviscapine on the vascular dementia of rats被引量：1: 《中国药理通讯》2006年第4期19-20,共2页陈建国刘超王芳熊哲; These studies were supported by a grant from the National Distinguished Young Scientists of China （国家杰出青年科学基金）（No.30425024） to Dr. Chert J.; 关键词：血管性痴呆脑缺血大鼠模型黄芩素灯盏花素治疗效果

Effect of breviscapine on fractalkine expression in chronic hypoxic rats被引量：3: 《Chinese Medical Journal》2006年第17期1465-1468,共4页CHEN Xiao-ju CHENG De-yun YANG Li XIA Xiu-qiong GUAN Jian; This study was supported by a research grant from the National Natural Science Foundation of China(No.30370629).; Fractalkine （FKN） is the only known chemokine that fulfils the dual functions of an adhesive molecule and a soluble chemoattractant.1 FKN expression was reported increase in lungs of patients with severe pulmonary a...; 关键词：HYPOXIA pulmonary hypertension FRACTALKINE BREVISCAPINE

Clinical Observation on Breviscapine in Treating Hypertension Patients Complicated with Micro-albuminuria of Renal Impairment被引量：3: 《Chinese Journal of Integrated Traditional and Western Medicine》2005年第1期31-33,共3页卫苓谭劼; Objective: To evaluate the efficacy of Breviscapine on essential hypertension (EH) patients complicated with micro-albuminuria of renal impairment. Methods: Seventy-six EH patients were randomly assigned to the contro...; 关键词：BREVISCAPINE essential hypertension micro-albuminuria renal impairment

BREVISCAPINE