Sudden cardiac death(SCD)is an unexpected cardiac death that is instantaneous or occurs within a short period of time after onset of symptoms,in a person in a stable state of health.SCD has either a certain etiology(f...
The effect of aqueous extract of the leaves of Chromolaena odorata on body weight, organ sizes, lipid profiles and atherogenic indices was investigated in normal and sub-chronic salt-loaded rats. The normal and treatm...
Aim: To investigate the influence of breviscapine on high glucose-induced hypertrophy of cardiomyocytes and the relevant mechanism in vitro and in vivo. Methods: Cultured neonatal cardiomyocytes were divided into i...
Project supported by the National Natural Science Foundation of China,№ 30170346.
AIM: To study the effects of N-[4-[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl] methanesulfonamide dihydrochloride dihydrate (E-4031), a specific Ikblocker, on Ca2= transient and cell contraction o...
AIM: To study the effects of serotonin (5-hydroxy-tryptamine, 5-HT) on transient outward potassium current (Ito) and elucidate its mechanism in rat ventricular myo-cytes. METHODS: Ito was recorded using the conven-tio...
Project supported by the National Natural Science Foundation of China, № 39500177.
AIM: To study the effects of 5-hydroxytryptamine (5-HT) on L-type calcium current (ICa) in norepine-phrine (ME)- induced hypertrophic ventricular myocytes. METHODS: Left ventricular hypertrophy was induced by injectin...
Project supported by Education Ministry of China (№ 0110-B042) and Education Committee of Guangzhou.
To investigate effects of simvastatin (Sim) on the activities of antioxidant enzymes and angiotensin-converting enzyme in rat myocardium with pressure-overload cardiac hypertrophy. METHODS-. Left ventricular hypertrop...
OBJECTIVE: To explore the pathogenic changes of myocardial apoptosis in heart hypertrophy during hypertension and evaluate the anti-apoptosis effect of Valsartan. METHODS: Thirty spontaneously hypertensive rats (SHRs)...
Project supported by the Education Committee Foundation of Anhui (№ 99j10219) and Health Special Foundation of Anhui, China.
Endoxin is a factor with a digitalis-like biological activity. It is a Na+ pump inhibitor and may be an endogenous medium of digitalis receptor. There are abnormal plasma levels of endoxin in some pathophysiologic sta...