HYPOXIC

作品数：306被引量：941H指数：15
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相关领域：医药卫生更多>>
相关作者：谭双香戴爱国胡瑞成丁艳洁蒋犁更多>>
相关机构：首都医科大学南华大学北京大学第一医院中国医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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AD-16 Protects Against Hypoxic-Ischemic Brain Injury by Inhibiting Neuroinflammation
《Neuroscience Bulletin》2022年第8期857-870,共14页Zhihua Huang Zhengwei Luo Andrea Ovcjak Jiangfan Wan Nai-hong Chen Wenhui Hu Hong-Shuo Sun Zhong-Ping Feng 
This work was supported by the Canadian Institutes of Health Research(CIHR PJT-153155);ZPF and a Natural Sciences and Engineering Research Council of Canada Discovery Grant(NSERC RGPIN-2016-04574)to HSS.
Neuroinflammation is a key contributor to the pathogenic cascades induced by hypoxic-ischemic(HI)insult in the neonatal brain.AD-16 is a novel anti-inflammatory compound,recently found to exert potent inhibition of th...
关键词：NEUROINFLAMMATION Neonatal hypoxic-ischemic brain injury NEUROPROTECTION AD-16 
WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation被引量：10
《Neuroscience Bulletin》2017年第3期292-298,共7页Dahu Li Lijun Zhang Xin Huang Lili Liu Yunling He Lun Xu Yiyao Zhang Tong Zhao Liying Wu Yongqi Zhao Kuiwu Wu Yan Wu Ming Fan Lingling Zhu 
supported by the National Natural Science Foundation of China(31401000 and 81430044);the Youth Medicine Program of the People’s Liberation Army of China(13QNP148);the National Basic Research Development Program(973 Program)of China(2012CB518200);the Integrated Drug Discovery Technology Platform of National Science and Technology Major Projects for‘‘Major New Drugs Innovation and Development’’,China(2012ZX09J12201-005)
The hypobaric hypoxic environment in highaltitude areas often aggravates the severity of inflammation and induces brain injury as a consequence. However, the critical genes regulating this process remain largely unkno...
关键词：Hypobaric hypoxia Inflammation Brain injury WIP1 phosphatase Lipopolysaccharide 
Time-dependent effect of combination therapy with erythropoietin and granulocyte colony-stimulating factor in a mouse model of hypoxic-ischemic brain injury被引量：4
《Neuroscience Bulletin》2014年第1期107-117,共11页Ji Hea Yu Jung Hwa Seo Jong Eun Lee Ji Hoe Heo Sung-Rae Cho 
supported by grants from the National Research Foundation(NRF-2010-0020408);funded by the Ministry of Education;Science and Technology;Republic of Korea
Erythropoietin （EPO） and granulocyte colony- stimulating factor （G-CSF） are likely to play broad roles in the brain. We investigated the effects of combination therapy with EPO and G-CSF in hypoxic- ischemic brain...
关键词：ERYTHROPOIETIN granulocyte colony-stimulating factor hypoxia-inducible factor-1 hypoxic-ischemic brain injury 
Progesterone treatment before experimental hypoxia-ischemia enhances the expression of glucose transporter proteins GLUT1 and GLUT3 in neonatal rats被引量：7
《Neuroscience Bulletin》2013年第3期287-294,共8页Xinjuan Li Hua Han Ruanling Hou Linyu Wei Guohong Wang Chaokun Li Dongliang Li 
supported by the National Natural Science Foundation of China (81100912);the Science Foundation of Xinxiang Medical University, China (CL and ZD 2009-63);the Science and Technology Project of Henan Province, China (092102310098)
Progesterone is an efficient candidate for treating stroke and traumatic brain damage. The current study was designed to investigate the effects of pro gesterone on glucose transporter proteins （GLUT1 and GLUT3） dur...
关键词：hypoxic-ischemic injury PROGESTERONE GLUT1 GLUT3 stroke 
Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury
《Neuroscience Bulletin》2011年第4期275-285,共11页Daniel Alonso-Alconada Antonia Alvarez Enrique Hilario 
supported by grants from Fondo de Investigación Sanitaria of Spanish Ministry of Health(PS09/02326);the Basque Government(GCI-07/79,IT-287-07)
Perinatal hypoxia-ischemia remains the single most important cause of brain injury in the newborn, leading to death or lifelong sequelae. Because of the fact that there is still no specific treatment for perinatal bra...
关键词：perinatal hypoxia-ischemia brain injury neuroprotective strategies endocannabinoid system 
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