Supported by National Natural Science Foundation of China,Key Project,No.82430071;The Scientific Research Program of FuRong Laboratory,No.2023SK2108;Clinical Medical Research Center for Viral Hepatitis of Hunan Province,No.2023SK4009;Hunan Provincial Natural Science Foundation,No.2023JJ60440;Hunan Provincial Health Commission Research Program,No.C202303088786.
BACKGROUND Hepatitis B virus(HBV)evades the innate immunity and leads to persistent chronic infection,but the molecular mechanism is still not well known.AIM To investigate whether HBV-miR-3 is involved in HBV immune ...
financially supported by“Nature Science Foundation of Fujian Province”(No.2020J01671,2021J01830).
IKKε is an IκB kinase participating in the control of NF-κB and type Ⅰ IFN signal pathways in mammals.However,the function of IKKε in regulating immune response is largely unknown in teleost.Herein,an IKKε homol...
supported by grants from the Ministry of Science and Technology of the People’s Republic of China(No.2022YFA1104003 to Hongquan Zhang and No.2021YFC2501003 to Hongquan Zhang);the National Natural Science Foundation of China(No.82073076 to Yu Yu,No.82372992 to Yu Yu,No.82230094 to Hongquan Zhang and No.81972616 to Hongquan Zhang,and No.82372451 to Xiaoguang Liu).
Ossification of the posterior longitudinal ligament(OPLL)is a condition comprising ectopic bone formation from spinal ligaments.This disease is a leading cause of myelopathy in the Asian population.However,the molecul...
supported by Macao Science and Technology Development Fund,0058/2020/A,0018/2023/AMJ,011/AIJ/2020 and 0003/2021/AKP;Swedish Research Council(Vetenskapsrådet)2019-01884;Swedish Cancer Foundation(Cancerfonden)200680 Pj;CIMED FoUI-975445.
Pattern recognition receptors are an essential part of the immune system,which detect pathogen-associated molecular patterns(PAMPs)and damage-associated molecular patterns(DAMPs)and help shape both innate and adaptive...