ISOLIQUIRITIN

作品数:5被引量:21H指数:3
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相关领域:医药卫生更多>>
相关作者:刘扬杨峻山张力勤更多>>
相关机构:中国医学科学院北京协和医学院北京大学更多>>
相关期刊:《Journal of Chinese Pharmaceutical Sciences》《Chinese Chemical Letters》《Acta Pharmaceutica Sinica B》《中国药理学与毒理学杂志》更多>>
相关基金:国家自然科学基金更多>>
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De novo biosynthesis of liquiritin in Saccharomyces cerevisiae被引量:11
《Acta Pharmaceutica Sinica B》2020年第4期711-721,共11页Yan Yin Yanpeng Li Dan Jiang Xianan Zhang Wei Gao Chunsheng Liu 
supported by the National Natural Science Foundation of China(No.81773838);the National Program for Special Support of Eminent Professionals;the Key Project at central government level(No.2060302,China).
Liquiritigenin(LG),isoliquiritigenin(Iso-LG),together with their respective glycoside derivatives liquiritin(LN)and isoliquiritin(Iso-LN),are the main active flavonoids of Glycyrrhiza uralensis,which is arguably the m...
关键词:GLYCYRRHIZA uralensis LIQUIRITIN ISOLIQUIRITIN LIQUIRITIGENIN ISOLIQUIRITIGENIN HETEROLOGOUS synthesis Saccharomyces cerevisiae 
Neuroprotective effect of isoliquriitin on corticosterone-induced apoptosis in PC12 cells被引量:1
《中国药理学与毒理学杂志》2017年第5期467-467,共1页LI Xiao GONG Wen-xia ZHOU Yu-zhi QIN Xue-mei 
The project supported by National Natural Science Foundation of China(81673572);the Applied Basic Research Project of Shanxi Province(201601D021164);Innovation Project of Higher Education Institutions in Shanxi Province(2016120)
OBJECTIVE Isoliquiritin,a flavonoid glycosides compound,possess a broad spectrum of pharmacological activities including antioxidant,antiinflammatory. However,rare studies in the field of isoliquiritin antidepressant-...
关键词:ISOLIQUIRITIN NEUROTOXICITY oxidative stress mitochondria apoptotic calcium 
Intestinal permeability of liquiritin and isoliquiritin in the Caco-2 cell monolayer model被引量:3
《Journal of Chinese Pharmaceutical Sciences》2010年第6期451-458,共8页张力勤 黄应栋 杨秀伟 
National New Drug R & D Program(Grant No. 2009ZX09301-010);National High Technology Program(Grant No. 2002AA2Z343C,2004AA2Z3783) of China;Ability Enhancing Project of National Science Fund for Talent Training in Basic Science(Grant No.J0830836)
The intestinal permeability of two flavonoid compounds liquiritin (LQ) and isoliquiritin (ILQ) was investigated using the Caco-2 cell monolayer model. In order to evaluate the permeability and predict the absorpti...
关键词:LIQUIRITIN ISOLIQUIRITIN Caco-2 cell monolayer model Intestinal permeability 
Determination of Liquiritigenin, Liquiritin, Isoliquiritigenin and Isoliquiritin in Extract of Traditional Chinese Medicine Sijunzi Decoction by High-Performance Liquid Chromatography被引量:4
《Journal of Chinese Pharmaceutical Sciences》2005年第4期227-230,共4页刘扬 杨峻山 
Aim An HPLC-UV method for the analysis of Traditional Chinese Medicine (TCM) preparation, Sijunzi decoction, has been developed. Four flavonoid marker compounds, liquiritigenin, liquiritin, isoliquiritigenin, and is...
关键词:traditional Chinese medicine Sijunzi decoction  HPLC 
The First Total Synthesis of Isoliquiritin被引量:2
《Chinese Chemical Letters》2002年第10期929-930,共2页Ya Ping WANG Liang Xi LI Qing Lian WANG Yu Lin LI 
A first total synthesis of isoliquiritin was accomplished starting from p-hydroxybenzaldehyde and 2,4-dihydroxyacetylphenone. The key step is condensation reaction. In synthetic process need not protect the hydroxy gr...
关键词:SYNTHESIS ISOLIQUIRITIN flavonoid glycosides. 
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