supported by the National Natural Science Foundation of China(No.81773838);the National Program for Special Support of Eminent Professionals;the Key Project at central government level(No.2060302,China).
Liquiritigenin(LG),isoliquiritigenin(Iso-LG),together with their respective glycoside derivatives liquiritin(LN)and isoliquiritin(Iso-LN),are the main active flavonoids of Glycyrrhiza uralensis,which is arguably the m...
The project supported by National Natural Science Foundation of China(81673572);the Applied Basic Research Project of Shanxi Province(201601D021164);Innovation Project of Higher Education Institutions in Shanxi Province(2016120)
OBJECTIVE Isoliquiritin,a flavonoid glycosides compound,possess a broad spectrum of pharmacological activities including antioxidant,antiinflammatory. However,rare studies in the field of isoliquiritin antidepressant-...
National New Drug R & D Program(Grant No. 2009ZX09301-010);National High Technology Program(Grant No. 2002AA2Z343C,2004AA2Z3783) of China;Ability Enhancing Project of National Science Fund for Talent Training in Basic Science(Grant No.J0830836)
The intestinal permeability of two flavonoid compounds liquiritin (LQ) and isoliquiritin (ILQ) was investigated using the Caco-2 cell monolayer model. In order to evaluate the permeability and predict the absorpti...
Aim An HPLC-UV method for the analysis of Traditional Chinese Medicine (TCM) preparation, Sijunzi decoction, has been developed. Four flavonoid marker compounds, liquiritigenin, liquiritin, isoliquiritigenin, and is...
A first total synthesis of isoliquiritin was accomplished starting from p-hydroxybenzaldehyde and 2,4-dihydroxyacetylphenone. The key step is condensation reaction. In synthetic process need not protect the hydroxy gr...