云南高校图书馆联盟文献共享服务平台- LIQUIRITIN

LIQUIRITIN: 作品数：11被引量：33H指数：4; 导出分析报告; 相关领域：医药卫生农业科学更多>>; 相关作者：刘扬杨峻山张力勤王丹侯俊玲更多>>; 相关机构：中国医学科学院北京协和医学院北京大学北京中医药大学教育部更多>>; 相关期刊：《Chinese Herbal Medicines》《Reproductive and Developmental Medicine》《Signal Transduction and Targeted Therapy》《Chinese Journal of Chemical Engineering》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中央级公益性科研院所基本科研业务费专项更多>>

Liquiritin ameliorates metabolic and endocrine alterations in a mouse model of polycystic ovary syndrome: 《Reproductive and Developmental Medicine》2022年第2期104-112,共9页Zhi Li Yan Liu Hai-Ou Liu Zhi-Yong Wu Cong-Jian Xu Fei-Fei Zhang; This work was supported by the Shanghai Commission of Science and Technology Planning(22ZR1409100)to F.Z;the Shanghai Municipal Commission of Health and Family Planning(2017ZZ01016)to C.X.; Objective::Altered bile acid transformation induces low-grade chronic inflammation and may play an important role in the pathophysiology of polycystic ovary syndrome (PCOS). Liquiritincan regulate bile acid metabolism...; 关键词：LIQUIRITIN Metabolic phenotypes Polycystic ovary syndrome Reproductive phenotypes

甘草苷对刀豆蛋白A诱导的实验性肝损伤的保护作用及机制被引量：1: 《牡丹江医学院学报》2022年第3期16-19,79,共5页文怡欣鄂志野张珊聂影鞠宝玲张红军; 黑龙江省省属高等学校基本科研业务费项目(2020-KYYWF-0781)。; 目的探讨甘草苷(Liquiritin,Liq)对刀豆蛋白A(Concanavalin A,ConA)诱导的实验性肝损伤的保护作用及作用机制。方法将ICR小鼠雌雄各半随机分为四组:对照组、ConA模型组、药物治疗中剂量组(ConA+Liq40 mg/kg)、药物治疗高剂量组(ConA+L...; 关键词：LIQUIRITIN CONA 免疫性肝损伤 HSC ActivinA

De novo biosynthesis of liquiritin in Saccharomyces cerevisiae被引量：11: 《Acta Pharmaceutica Sinica B》2020年第4期711-721,共11页Yan Yin Yanpeng Li Dan Jiang Xianan Zhang Wei Gao Chunsheng Liu; supported by the National Natural Science Foundation of China(No.81773838);the National Program for Special Support of Eminent Professionals;the Key Project at central government level(No.2060302,China).; Liquiritigenin(LG),isoliquiritigenin(Iso-LG),together with their respective glycoside derivatives liquiritin(LN)and isoliquiritin(Iso-LN),are the main active flavonoids of Glycyrrhiza uralensis,which is arguably the m...; 关键词：GLYCYRRHIZA uralensis LIQUIRITIN ISOLIQUIRITIN LIQUIRITIGENIN ISOLIQUIRITIGENIN HETEROLOGOUS synthesis Saccharomyces cerevisiae

Biomolecular network-based synergistic drug combination discovery:a combination of paeoniflorin and liquiritin alleviates neuropathic pain by inhibiting neuroinflammation via suppressing the chemokine signaling pathway被引量：4: 《Signal Transduction and Targeted Therapy》2020年第1期1804-1806,共3页Qiuyan Guo Weijie Li Chao Wang Xia Mao Xiaoyue Wang Wenjia Chen Haiyu Xu Qian Wang Yanqiong Zhang Na Lin; funded by the National Natural Science Foundation of China(81630107);National Key Research and Development Program of China(2019ZX09731-002 and 2018YFC1705201);Fundamental Research Funds for the Central Public Welfare Research Institute(Z2017082,L2017018,and ZXKT19013);the Key Laboratory of Beijing for the Identification and Safety Evaluation of Chinese Medicine,Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,China(BZ0328).; Dear Editor,Neuropathic pain(NP)resulting from injuries or diseases affecting the somatosensory nervous system is highly prevalent in various pathological conditions.1 Since NP is debilitating and impacts health and t...; 关键词：pain inflammation INHIBITING

Protective effect of liquiritin on oxidative stress injury of SH-EP1 cell lines caused by hydrogen peroxide: 《Journal of Hainan Medical University》2017年第1期4-7,共4页Ning Shi Hong-ju Guo Huan Wang Yu-Xin Fan Yu-Min Zhang Li-Rong Chang; Surface Project of Natural Science Foundation of China No:3077263.; Objective:To study the protective effect of liquiritin on the oxidative stress injury of SH-EP1 cell lines caused by hydrogen peroxide.Methods: SH-EP1 cell lines were cultured and randomly divided into control group, ...; 关键词：LIQUIRITIN NEURON Oxidative stress MITOCHONDRIA Antioxidant

LC–MS/MS Method for Quantification of Liquiritigenin in Rat Plasma: Application to Pharmacokinetic Study of Liquiritin被引量：2: 《Chinese Herbal Medicines》2016年第1期53-60,共8页Shi-qi Dong Hui-rong Fan Quan-sheng Li Guang-li Wei Ya-zhuo Li Chang-xiao Liu Duan-yun Si; "Twelfth Five-year Plan"-Major Technological Projects of "Creation of Major New Drug"(2012ZX09506-001);National 973 Program of China(2010CB933900);Tianjin Science and Technology Plan Project(10SYSYJC28600); Objective A simple, sensitive, and rapid LC-MS/MS method has been established and validated for the determination of liquiritigenin （LG） in rat plasma. Methods Naringenin was chosen as internal standard （IS）. LG a...; 关键词：LC-MS/MS LIQUIRITIGENIN LIQUIRITIN PHARMACOKINETICS

Effect of strychnine hydrochloride on liver cytochrome P450 mRNA expression and monooxygenase activities in rat被引量：2: 《Acta Pharmaceutica Sinica B》2011年第2期121-128,共8页Qian Gao Jun-jun Wang Feng-mei Han Yong Chen; This work was financially supported by the Natural Science Foundation of China(Grant number 30630075).; Strychnos nux-vomica L.has been frequently used in traditional Chinese medicine but has high acute toxicity.It is commonly taken with Glycyrrhizae radix to decrease its toxicity but the mechanism of this interaction i...; 关键词：STRYCHNINE CYP450 Compatibility Glycyrrhetic acid LIQUIRITIN

Effect of Different Concentrations of Mo on Yield and Accumulation of Active Constituents of Glycyrrhiza uralensis Fisch被引量：2: 《Agricultural Science & Technology》2010年第11期17-20,共4页王丹万春阳侯俊玲王文全李卫东魏胜利; Supported by Natural Science Foundation of China(30572328)~~; [Objective] The aim was to explore the effects of different concentrations of molybdenum（Mo）on the growth,yield and the accumulations of active constituents of Glycyrrhiza uralensis.[Method] The seedlings of one-yea...; 关键词：MOLYBDENUM Glycyrrhiza uralensis YIELD Glycyrrhizic acid LIQUIRITIN

Intestinal permeability of liquiritin and isoliquiritin in the Caco-2 cell monolayer model被引量：3: 《Journal of Chinese Pharmaceutical Sciences》2010年第6期451-458,共8页张力勤黄应栋杨秀伟; National New Drug R & D Program(Grant No. 2009ZX09301-010);National High Technology Program(Grant No. 2002AA2Z343C,2004AA2Z3783) of China;Ability Enhancing Project of National Science Fund for Talent Training in Basic Science(Grant No.J0830836); The intestinal permeability of two flavonoid compounds liquiritin （LQ） and isoliquiritin （ILQ） was investigated using the Caco-2 cell monolayer model. In order to evaluate the permeability and predict the absorpti...; 关键词：LIQUIRITIN ISOLIQUIRITIN Caco-2 cell monolayer model Intestinal permeability

Microwave-assisted Micellar Extraction and Determination of Glycyrrhizic Acid and Liquiritin in Licorice Root by HPLC被引量：4: 《Chinese Journal of Chemical Engineering》2007年第4期474-477,共4页孙晨谢渝春刘会洲; Supported by the National Science Fund for Creative Research Groups （No.20221603）, the National Natural Science Foundation of China Key Project （No.20490200） and PetroChina.; The feasibility of emploving non-ionic surfactant （Triton X-100） as an alternative and effective solventfor the microwave-assisted extraction of glycyrrhizic acid （GA） and liquiritin （LQ） from licorice root was ...; 关键词：microwave-assisted micellarextraction cloud-point extraction Triton X-100 glycyrrhizic acid LIQUIRITIN

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