云南高校图书馆联盟文献共享服务平台- STRYCHNINE

STRYCHNINE: 作品数：11被引量：22H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王丽佳蔡宝昌郭建芳吴自俊服部征雄更多>>; 相关机构：江西省公安厅富山医科药科大学天津医科大学陕西省中医药研究院更多>>; 相关期刊：《Transactions of Tianjin University》《Asian Pacific Journal of Tropical Biomedicine》《Journal of Traditional Chinese Medicine》《Chinese Herbal Medicines》更多>>; 相关基金：国家自然科学基金更多>>

Effect of Baizhu(Rhizoma Atractylodis Macrocephalae)extract on intestinal absorption of brucine and strychnine in vitro and in situ被引量：4: 《Journal of Traditional Chinese Medicine》2020年第4期562-570,共9页Lu Dan Jiang Qieying Zhang Jing Zeng Ronggui Liao Zhenggen Liang Xinli; the National Natural Science Foundation of China(No.81660757 and No.81303237);the Academic and Technological Foregoer Funds of Jiangxi Province,China(No.20162BCB22015);the Project on Cultivation of Medical Elite(Gan Po Ying Cai 555)(2013296);the Youth Science Funds of Jiangxi Province,China(No.20153BCB23019);the National Natural Science Foundation of Jiangxi Province(No.20161ACB21020);the Natural Science Research Project of Huaian(No.HAB201716)。; OBJECTIVE:To investigate the antagonistic effect of the extract of Baizhu(Rhizoma Atractylodis Macrocephalae)(RAM)on the intestinal absorption of brucine and strychnine in Strychnos nux-vomica(NUX)and propose the mech...; 关键词：Strychnos nux-vomica BRUCINE STRYCHNINE ATP binding cassette transporter subfamily B member 1 Baizhu(Rhizoma Atractylodis Macrocephalae)

The pharmacological and toxicological action of strychnine on central nervous system: 《Asian Journal of Traditional Medicines》2020年第2期76-86,共11页Taotao Wang Qian Yang Rong Gao Jianxiu Zhai Jun Yin; Strychnine is the main bioactive constituent responsible for the pharmacological and toxic properties of strychnos nux-vomica L.(Loganiaceae),which is known for severe neurotoxicity.Although its toxic threshold is eas...; 关键词：STRYCHNINE PHARMACOLOGICAL activities NEUROTOXICITY mechanisms

Microstructure, Content and in vitro Release of Brucine and Strychnine in Strychnos Nux-Vomica Powder with Different Particle Sizes被引量：4: 《Transactions of Tianjin University》2014年第6期444-450,共7页倪力军赵雯雯张立国王南南; Supported by the Plan Issue of Shanghai Science &Technology Committee(No.13401901100); To explore the effect of particle size on the quality uniformity and in vitro release performance of Strychnos nux-vomica powder, seven samples of Strychnos nux-vomica powder with different particle sizes were prepare...; 关键词：strychnos nux-vomica BRUCINE STRYCHNINE PARTICLE size quality UNIFORMITY in VITRO release

Toxic effects of strychnine and strychnine N-oxide on zebrafish embryos被引量：2: 《Chinese Journal of Natural Medicines》2014年第10期760-767,共8页LI Yu QI Xu YANG Yu-Wei PAN Yang BIAN Hui-Min; supported by The Opening Project of Jiangsu Key Laboratory for Chinese Medicine Processing(ZYPZ010);the National Natural Science Foundation of China(81373295); AIM: The application of strychnine(S) is limited due to its toxicity; strychnine N-oxide(SNO) is a derivative of strychnine. The aim was to employ zebrafish embryos to investigate and compare the developmental toxicit...; 关键词：STRYCHNINE Strychnine N-oxide TOXICITY Zebrafish embryos APOPTOSIS

Antiepileptic activity of lobeline isolated from the leaf of Lobelia nicotianaefolia and its effect on brain GABA level in mice: 《Asian Pacific Journal of Tropical Biomedicine》2012年第7期537-542,共6页Abrar M Tamboli Rukhsana A Rub Pinaki Ghosh SL Bodhankar; Supported by University of Pune(Grant No.BCUD/OSD/390); Objective:To investigate the anticonvulsant activity of the lobeline isolated from the Lobelia nicotianaefolia in chemoconvulsant-induced seizures and its biochemical mechanism by investigating relationship between se...; 关键词：LOBELIA nicotianaefolia Lobeline BRAIN GABA level ANTIEPILEPTIC activity Pentylenetetrazol(PTZ) STRYCHNINE

In vitro Metabolism of Strychnine by Human Cytochrome P450 and Its Interaction with Glycyrrhetic Acid被引量：6: 《Chinese Herbal Medicines》2012年第2期118-125,共8页Li LIU Juan XIAO Zhi-hong PENG Wen-hua WU Peng DU Yong CHEN; National Natural Science Foundation of China (30630075); Objective To investigate the metabolism of strychnine(STN)and the metabolic interaction between STN and glycyrrhetic acid(GA)in vitro.Methods Human liver microsomes(HLM)and human recombinant cytochrome P450(CYP)isofor...; 关键词：cytochrome P450 glycyrrhetic acid human liver microsomes METABOLISM STRYCHNINE

Determination of strychnine and brucine in traditional Chinese medicine preparations by capillary zone electrophoresis with micelle to solvent stacking被引量：2: 《Chinese Chemical Letters》2011年第3期330-333,共4页Xiao Fang Yin Zhi Li Shuai Hua Zhang Chun Xia Wu Chun Wang Zhi Wang; supported by the Natural Science Foundations of Hebei(NoB2010000657); A novel micelle to solvent stacking on-line sample preconcentration technique in capillary zone electrophoresis（MSS-CZE） has been developed to determine the strychnine and brucine in traditional Chinese medicine pre...; 关键词：On-line sample preconcentration Micelle to solvent stacking Capillary zone electrophoresis STRYCHNINE BRUCINE Traditional Chinese medicine preparation

Effect of strychnine hydrochloride on liver cytochrome P450 mRNA expression and monooxygenase activities in rat被引量：2: 《Acta Pharmaceutica Sinica B》2011年第2期121-128,共8页Qian Gao Jun-jun Wang Feng-mei Han Yong Chen; This work was financially supported by the Natural Science Foundation of China(Grant number 30630075).; Strychnos nux-vomica L.has been frequently used in traditional Chinese medicine but has high acute toxicity.It is commonly taken with Glycyrrhizae radix to decrease its toxicity but the mechanism of this interaction i...; 关键词：STRYCHNINE CYP450 Compatibility Glycyrrhetic acid LIQUIRITIN

Study on the Interaction between Strychnine and Bovine Serum Albumin by Capillary Electrophoretic Frontal Analysis被引量：2: 《Chinese Chemical Letters》2005年第9期1233-1236,共4页Shao Ping FU Xiao Zhe ZHANG Feng ZHANG Qing XU Hong Bin XIAO Xin Miao LIANG; The authors are grateful to the National Natural Science Foundation of China(Grant No.20235020 and 20372062)for financial support.; The protein binding constant, binding sites of the Strychnos alkaloid-strychnine and bovine serum albumin （BSA） was determined by capillary electrophoretic frontal analysis （CE-FA） for the first time. The experime...; 关键词：STRYCHNINE binding constant capillary electrophoretic frontal analysis bovine serumalbumin

ANALYSIS OF STRYCHNINE ALKALOIDS IN BIOLOGICAL SAMPLES BY THIN-LAYER CHROMATOGRAPHIC DENSITOMETRY AND DISTRIBUTION STUDY OF STRYCHNINE IN INTOXICATED RATS: 《Journal of Pharmaceutical Analysis》1998年第2期146-149,180,共5页傅强贺浪冲常春苗治平; A sensitive and rapid analytical procedure was established to detrmine strychnie alkaloids in diverse biological specimens. Samples were treated with hydrochloric acid to precipitate protein and scanned in thin-layer ...; 关键词：STRYCHNINE ALKALOIDS biological samples toxicological analysis thin-layer chromatographic densitometry

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