IVABRADINE

作品数:22被引量:60H指数:3
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相关领域:医药卫生更多>>
相关作者:沈法荣王丽娟孙磊徐秀琴肖鹏更多>>
相关机构:浙江医院北京中医药大学东方医院济宁市精神病防治院北京中日友好医院更多>>
相关期刊:《World Journal of Cardiology》《World Journal of Cardiovascular Diseases》《临床心血管病杂志》《养生保健指南(医药研究)》更多>>
相关基金:国家自然科学基金更多>>
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HCN4与心律失常相关性及其抑制剂研究进展
《中文科技期刊数据库(文摘版)医药卫生》2024年第7期0001-0008,共8页李一菲 祝新宇 殷婕 刘丽萍 郭毅飞 
国家自然科学基金面上项目(61671098);大连市科技惠民项目(2022JJ13SN074)。
超级化激活环核苷酸门控通道4(HCN4)与心脏起搏运动有关,它可以通过控制心率来调节人体正常的生理功能。研究发现,心律失常的原因之一是HCN4通道功能丧失或获得。该综述总结了关于HCN4通道突变的一些研究,旨在进一步证实HCN4与心律失常...
关键词:HCN4 心律失常 IVABRADINE 抑制剂 临床研究 
Meta-analysis of Traditional Chinese Medicine combined with Ivabradine in the Treatment of Chronic Heart Failure
《Journal of Hainan Medical University》2023年第9期60-66,共7页OUYANG Jia-hui ZHANG Miao DU Tian-yi GAO Zhu-ye LI Li-zhi 
National 12th Five-Year Science and Technology Support Plan(No.2013BAI02B01);National Key Science and Technology Project of"Major New Drug Creation"(No.2019ZX09201005-002-006);Beijing TCM Science and Technology Development Fund Project(No.JJ-2020-79);Science and Technology Innovation Project of China Academy of Chinese Medical Sciences(No.CI2021A00920)。
Objective:To systemically evaluate clinical efficacy and safety of traditional Chinese medicine(TCM)combined with ivabradine(IVA)in the treatment of chronic heart failure(CHF).Method:We searched China National Knowled...
关键词:Chronic Heart Failure Traditional Chinese Medicine IVABRADINE META-ANALYSIS 
CHANGES IN NEUROPEPTIDES AFTER MUSIC EXPOSURE 429Cardioprotective effect of ivabradine via the AMPK/SIRT1/PGC-1αsignaling pathway in myocardial ischemia/reperfusion injuryinduced in H9c2 cell
《BIOCELL》2020年第3期431-441,共11页XINGXING ZHU TIANFENG HUA MINGFEI WU JIATIAN WU JIANCHAO HONG MIN YANG 
the National Natural Science Foundation Youth Science Foundation(No.81601661);the Science Foundation for Post-doctoral researchers in Anhui Province of China(No.2016B140).
Post-resuscitation myocardial dysfunction(PRMD)is the most severe myocardial ischemia-reperfusion injury(MIRI)and is characterized by difficult treatment and poor prognosis.Research has shown the protective effects of...
关键词:IVABRADINE Myocardial ischemia REPERFUSION injury Energy metabolism Oxidative stress AMPK/SIRT1/PGC-1α pathway 
Effect of ivabradine in the treatment of acute exacerbation of chronic obstructive pulmonary disease with heart failure被引量:1
《Journal of Hainan Medical University》2019年第19期31-36,共6页Jing Z Qing G Li-hong Z Liang S Dong-xia LI Cui-cui G Guo-hong Y 
Objective: To observe the effectiveness and safety of ivabradine in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and heart failure. Methods:Patients who were admitted to hospital ...
关键词:IVABRADINE Acute exacerbation of chronic obstructive pulmonary disease Heart failure Heart rate 
Ivabradine—The Final Crusader for Postoperative Junctional Ectopic Tachycardia, a Case Report with Literature Review
《World Journal of Cardiovascular Surgery》2019年第8期73-82,共10页Manoj Kumar Sahu Harsha Vardhan Niraghatam Nikhil Bansal Sarvesh Pal Singh Palleti Rajashekar Shiv Kumar Choudhary 
Background: Junctional ectopic tachycardia (JET) is one troublesome supraventricular arrhythmia in postoperative pediatric cardiac surgical patients. Unless treated timely and effectively it may lead to morbidity and ...
关键词:Tetralogy of Fallot JUNCTIONAL ECTOPIC TACHYCARDIA IVABRADINE 
Effects of ivabradine on Notch and NF-kappa B signaling pathway in myocardial cells of rats with myocardial infarction被引量:1
《Journal of Hainan Medical University》2019年第11期9-13,共5页Ting-Yu Wu Huan-Huan Hu Cheng Chen 
Objective:To investigate the effects of ivabradine on Notch and NF-kappa B signaling pathway in myocardial cells of rats with myocardial infarction.Methods: The model of myocardial infarction was established by ligati...
关键词:IVABRADINE Myocardial INFARCTION NOTCH NF-KAPPA B Cardiac function VENTRICULAR REMODELING 
Ivabradine tolerability in heart failure被引量:1
《Journal of Geriatric Cardiology》2018年第11期708-709,共2页Sarah Birkhoelzer Daniel Stevens Donah Zachariah Jackie Taylor Nigel Rowell Paul R Kalra 
The Systolic Heart failure treatment with the I( inhibitor ivabradine Trial (SHIFT, n = 6505) evaluated patients with symptomatic chronic heart failure (CHF), in sinus rhythm with resting heart rate ≥70 beats/min and...
关键词:HEART FAILURE IVABRADINE Quality of life The ELDERLY 
Influences of Ivabradine treatment on serum levels of cardiac biomarkers sST2, GDF-15, suPAR and H-FABP in patients with chronic heart failure被引量:32
《Acta Pharmacologica Sinica》2018年第7期1189-1196,共8页Peter JIRAK Dzeneta FEJZIC Vera PAAR Bernhard WERNLY Rudin PISTULLI Ilonka ROHM Christian JUNG Uta C HOPPE P Christian SCHULZE Michael LICHTENAUER Atilla YILMAZ Daniel KRETZSCHMAR 
Chronic heart failure (CHF) represents a major cause of hospitalization and death. Recent evidence shows that novel biomarkers such as soluble suppression of tumorigenicity (sST2), growth-differentiation factor-15...
关键词:heart failure CARDIOMYOPATHY IVABRADINE heart rate biomarker sST2 GDF-15 SUPAR H-FABP 
Safety of ivabradine, a heart rate lowering drug: a systematic review and meta-analysis被引量:1
《Journal of Chinese Pharmaceutical Sciences》2017年第5期379-389,共11页肖锐锐 徐秀琴 孙磊 方晓磊 肖鹏 
As a novel heart rate lowing agent, ivabradine can reduce the heart rate by inhibiting the If (pacemaker) current in the sinoatrial node without affecting blood pressure or left ventricular systolic function. Howeve...
关键词:IVABRADINE Systematic review META-ANALYSIS SAFETY 
Ivabradine in the treatment of systolic heart failure- A systematic review and meta-analysis被引量:5
《World Journal of Cardiology》2017年第2期182-190,共9页Mahesh Anantha Narayanan Yogesh NV Reddy Janani Baskaran Abhishek Deshmukh David G Benditt Ganesh Raveendran 
AIM To perform a systematic-review and meta-analysis to compare outcomes of ivabradine combined with betablocker to beta-blocker alone in heart failure with reduced ejection fraction(HFr EF).METHODS We searched PubM e...
关键词:IVABRADINE Heart failure 
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