LETROZOLE

作品数：55被引量：107H指数：5
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Impact of alcoholic extract from sea cucumber(Holothuria parva)on letrozole-induced polycystic ovary syndrome in adult female rats
《Asian pacific Journal of Reproduction》2024年第6期261-270,共10页Samaneh Askari Mohammad Reza Jafarzadeh Shirazi Masoumeh Ahmadi Arezoo Khoradmehr Nadiar M.Mussin Asset A.Kaliyev Farzad Mohammad Rezazadeh Mohammad Dadpasand Taromsari Ali Bustani Nader Tanideh Kulyash R.Zhilisbayeva Amin Tamadon 
supported by Shiraz University,Vice-Chancellor of Research as a master thesis.
Objective:To explore the potential therapeutic impact of an alcoholic extract derived from the sea cucumber(Holothuria parva)on letrozole-induced polycystic ovary syndrome(PCOS)in adult female Sprague-Dawley rats.Meth...
关键词：Polycystic ovary syndrome Sea cucumber LETROZOLE METFORMIN RATS 
Effect of Down-regulation of MMP-2 by Quercetin on the Migration and Invasion of Uterine Fibroids Cells through the cAMP Signaling Pathway
《Chinese Journal of Biomedical Engineering(English Edition)》2024年第2期54-61,共8页LIN Shu-ping ZOU Xiao-fen 
Objective:To investigate the effect of down-regulation of matrix metalloproteinase-2(MMP-2)by down-regulating the cyclic adenosine monophosphate(cAMP)signaling pathway on the migration and invasion of uterine fibroids...
关键词：uterine fibroids LETROZOLE cAMP signaling pathway MMP-2 cell migration and invasion 
A novel herbal combination ameliorates ovarian dysfunction and regulates altered biochemical parameters in rats with letrozole-induced polycystic ovary syndrome
《Asian pacific Journal of Reproduction》2023年第1期23-34,共12页Sunita Shailajan Sasikumar Menon Swati Singh Yugandhara Patil 
supported by DST-SERB,Government of India via sanction No.EMR/2017/001106。
Objective:To investigate the potential activity of novel herbal combination and novel herbal formulation(syrup)in female Sprague Dawley rats with letrozole-induced polycystic ovary syndrome(PCOS).Methods:Forty-two rat...
关键词：Polycystic ovarian syndrome Polyherbal combination LETROZOLE Pushyanuga churna Clomiphene citrate HISTOPATHOLOGY Biochemical HERBAL 
Protective efficacy of dark chocolate in letrozole-induced ovary toxicity model rats: hormonal, biochemical, and histopathological investigation
《Journal of Traditional Chinese Medicine》2022年第5期741-748,共8页Naser Mirazi Sheida Hesami Alireza Nourian Abdolkarim Hosseini 
OBJECTIVE: To assess the protective effect of dark chocolate(DC) on the letrozole-induced rat model of polycystic ovary syndrome(PCOS). METHODS: In this experimental study, 32 female Wistar rats, weighing(200 ± 20) g...
关键词：CHOCOLATE LETROZOLE METFORMIN polycystic ovary syndrome antioxidants anti-inflammatory agents 
Pharmacological efficacy of the traditional Chinese medicinal formula Kun-Tai-1A in the treatment of letrozole-induced polycystic ovary syndrome
《Traditional Medicine Research》2022年第3期44-54,共11页Leanne Lee Leung Jing Xie Ya-Cun Chen Kar-Ho Lam Hei Wan Su-Lan Yu Tzi-Bun Ng George Pak-Heng Leung Jin Yu Ren-Min Yao Shu-Jia Sun Sydney Chi-Wai Tang Hai-Yong Chen Jia Zhao Zhang-Jin Zhang Calvin Kai-Fai Lee Kalin Yan-Bo Zhang Li-Xing Lao Yun Feng Xiang Lin Wei Meng 
Background:Polycystic ovary syndrome(PCOS)is an endocrine disorder that occurs in women of child-bearing age.Moreover,PCOS patients have decreased pregnancy rates and clomiphene citrate resistance.The traditional Chin...
关键词：polycystic ovary syndrome traditional Chinese medicine OVULATION Kun-Tai-1A SEAHORSE endocrine disease 
A Retrospective Study on the Use of High-Dose Letrozole while Undergoing Ovarian Stimulation for Oocyte and Embryo Cryopreservation in Cancer Patients
《Advances in Reproductive Sciences》2022年第1期19-26,共8页Rahana Harjee Jeffrey Roberts 
Objective: To determine the efficacy of letrozole in suppressing estradiol levels during ovarian stimulation in cancer patients. Methods: A retrospective chart review of cancer patients undergoing ovarian stimulation ...
关键词：Ovarian Stimulation Oocyte Preservation Fertility Preservation CANCER 
Effect of different modeling time on intestinal bacteria in letrozole induced PCOS rats
《Journal of Hainan Medical University》2022年第2期1-9,共9页Fan Jia Dong-Xue Zheng Ru-Feng Chen Hong-Yu Zhao Jin-Yuan Liu Li-Li Zhang Lin-Hua Zhao Yong-Mei Liu Yun Zhang Xiao-Yun Zhu Jie Kan Xin-Min Liu 
National Natural Science Foundation of China(No.81674011)。
Objective:The differences of ovarian morphology,reproductive hormones,glucose and lipid metabolism and intestinal bacteria in rats with polycystic ovary syndrome(PCOS)induced by triazole were compared.Method:Eighteen ...
关键词：Polycystic Ovarian syndrome Lyconazole Model Intestinal bacteria 
Estrogen augmented visceral pain and colonic neuron modulation in a double-hit model of prenatal and adult stress被引量：4
《World Journal of Gastroenterology》2021年第30期5060-5075,共16页Jing-Hong Chen Ying Sun Pei-Jun Ju Jin-Bao Wei Qing-Jie Li John H Winston 
NIDDK,No.5R01DK111819-03 and No.5R01DK032346-28;National Natural Science Foundation of China,No.81571326.
BACKGROUND Chronic stress during pregnancy may increase visceral hyperalgesia of offspring in a sex-dependent way.Combining adult stress in offspring will increase this sensitivity.Based on the evidence implicating es...
关键词：Chronic prenatal stress ESTROGEN Visceral pain Neuronal sensitization EXCITABILITY LETROZOLE 
Suppressed estrogen supply via extra-ovarian progesterone receptor membrane component 1 in menopause被引量：2
《The Journal of Biomedical Research》2021年第3期228-237,共10页Sang RLee Hyun Yang Seong Lae Jo Young Ho Lee Hye Won Lee Bae-keun Park Eui-Ju Hong 
This work was supported by a research fund of Chungnam National University(No.2020-0733-01);This work was supported by Research Scholarship of Chungnam National University.
In post-menopausal women,intra-mammary estrogen,which is converted from extra-ovarian estrone(E1),promotes the growth of breast cancer.Since the aromatase inhibitor letrozole does not suppress 17β-estradiol(E2)produc...
关键词：extra-ovarian Pgrmc1 steroid sulfatase ESTROGEN LETROZOLE 
Combined effects of Gymnema sylvestre and Pergularia daemia on letrozole-induced polycystic ovarian syndrome in rats
《Asian pacific Journal of Reproduction》2021年第2期68-74,共7页Sudhakar Pachiappan Kothai Ramalingam Arul Balasubramanian 
The authors are acknowledged to the Chancellor,Vinayaka Mission’s Research Foundation(Deemed to be University),Salem for providing necessary support for writing this article.
Objective:To investigate the combined therapeutic potential of Gymnema(G.)sylvestre and Pergularia(P.)daemia on letrozole-induced polycystic ovarian syndrome(PCOS)in rats.Methods:Thirty six healthy female Wistar rats ...
关键词：Polycystic ovarian syndrome METFORMIN LETROZOLE Gymnema sylvestre Pergularia daemia Reproductive hormone Estrus cycle 
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