BACKGROUND Drug-induced lung injury is a common adverse effect of chemotherapeutic agents.Diffuse alveolar hemorrhage(DAH)is a fatal complication associated with druginduced lung injury.Early diagnosis and treatment o...
In this editorial,we comment on the article by Zhao et al which highlighted how patients having nonalcoholic fatty liver disease(NAFLD)were more susceptible to drug-induced lung injury(DILI).This article looked at the...
supported by the 2020 Special Tasks for Military Health and Epidemic Prevention and Protection(grant number Hou Wei Han[2021]No.208);Hospital Project(grant number 2016ZD-008).
Background:The roles of the Pink1/Parkin pathway and mitophagy in lung injury during heat stroke remain unclear.In this study,we investigated the role of Pink1/Parkin-mediated mitophagy in acute lung injury(ALI)in rat...
supported by the grants from the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMY24H270002);the Zhejiang Provincial Medical and Health Technology Project(No.2023KY158);the Cultivation Program for Excellent Young Talents of Hangzhou First People’s Hospital(No.YQNYC202131);the Hangzhou Health Science and Technology Plan-Major Project(No.Z20220026).
Intestinal ischemia-reperfusion(I/R)injury severely affects the lungs.Germacrone(Ger)possesses anti-inflammatory and antioxidant properties.However,it is unclear whether it protects the lungs from I/R injury.In this s...
Project of Science,Technology Department of Yunnan Province and Kunming Medical University(No.202101AY070001-164)
To the Editor:Radiation therapy(RT)is important in treating thoracic tumors.However,RT inevitably causes damage to normal lungs,leading to radiation-induced lung injury(RILI).Physical and biological factors conjointly...
Nanjing Medical University Science and Technology Development Fund,Grant/Award Number:NMUB20220211;Huai'an Natural Science Research Program,Grant/Award Number:HAP202308。
Background:Sex is an independent risk factor for systemic sclerosis(SSc).Chemokine ligand 4(CXCL4)participates in SSc via multiple mechanisms.In the present study,we investigated the role of CXCL4 in sex-specific lung...
supported by the National Natural Science Foundation of China(grant no.U190420094).
Gas explosions are one of the most lethal types of coal mine safety accidents.The powerful shock waves these explosions produce can cause damage to the lung tissue of nearby individuals,resulting in symptoms including...
National Natural Science Foundation of China(grant No.52172288);Young Talent Support Plan of Xi'an Jiaotong University of China(grant No.QY6J003)。
Dysregulated inflammation after trauma or infection could result in the further disease and delayed tissue reconstruction.The conventional anti-inflammatory drug treatment suffers to the poor bioavailability and side ...
supported by the Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project under Grant(No.2023ZL140).
Objectives:This study explores the protective effects of glycyrrhizic acid(GA)on sepsis-induced cellular damage and inflammation in acute lung injury(ALI),specifically through the modulation of the sirtuin 1(SIRT1)and h...
In land warfare,trenches serve as vital defensive fortifications,offering protection to soldiers while engaging in combat.However,despite their protective function,soldiers often sustain injuries within these trenches...