supported by the National Natural Science Foundation of China[grant numbers 82103887];Hunan Provincial Natural Science Foundation of China[grant numbers 2021JJ30752 and 2021JJ40374];National Science Fund for Excellent Young Scholars of Hunan Province[grant numbers 2023JJ20032];Changsha Natural Science[grant numbers 45045]。
The pervasive utilization of industrial substances has escalated human exposure to cadmium(Cd),a metal associated with long-term negative health outcomes such as renal dysfunction,neurological disorders,and various ca...
This study was supported by 973 Program of China (2002 CB 512905).
To investigate the effects of cadmium exposure on insulin expression in rats. Methods Eighteen adult SD rats were administered cadmium subcutaneously (0.5, 1.0, and 2.0 mg/kg bw). The effects on endocrine of pancrea...
This work was supported by the National 973 Program of China 2002 CB 512905
Objective To study the gene expression of metallothionein 1 (MT-1) isoforms in human peripheral blood lymphocytes (HPBLs). Methods The expression of mRNA representing the seven active MT-I genes was determined in ...
This study was supported by 973 Program of China (2002 CB 512905).
Objective To study the possible intervention of isoflavones in cytotoxicity induced by cadmium in vascular endothelial cells. Methods An ECV 304 cell line derived from human umbilical vein endothelial cells was adopte...
Arsenic (As) intoxication was examined in freshwater climbing perch (Anadas testudineus) following in vivo treatment for 2d at 1/10 LD50 and for 30d at 1/20 LC50. These exposures elicited no mortality, nor any apparen...
The mechanism of action of cadmium in the inductive pathway of metallothionein (MT) synthesis was studied in the rat. Cadmium significantly elevated the MT leve by 872% which was antagonised by coadministration of eit...