supported by Ningxia Excellent Young Teachers Training Fund Project(No.NGY2018-74);the Key Research and Development Projects in Ningxia(No.2020BFG02010);the National Natural Science Foundation of China(No.31860290,81860268);Ningxia Science and Technology Innovation Leading Talent Training Project(No.2020GKLRLX11);Ningxia Medical University Research Project(No.XT2019017)。