supported by the National Basic Research Program of China(2011CB943900);the National Natural Science Foundation of China(31071145)
The biosafety issue of nanoscale materials is getting more and more attention with their increasing manufacture and application.In the research of cellular effects and underlying mechanisms related to toxicity of nano...
supported by grants from the Ministry of Science and Technology of China (No.2012CB910300);the National Natural Science Foundation of China (No.30525033);the Fundamental Research Funds for the Central Universities of China to X.-B.Q
Ubiquitination is crucial for cellular processes,such as protein degradation,apoptosis,autophagy,and cell cycle progression.Dysregulation of the ubiquitination network accounts for the development of numerous diseases...
Macrophage migration inhibitory factor (MIF) is overexpressed in numerous tumors and has been correlated with the development of breast cancer, but the mechanism(s) have largely remained unknown. Suppression of au...
Apoptosis and autophagy are important molecular processes that maintain organismal and cellular homeostasis, respectively. While apoptosis fulfills its role through dismantling damaged or unwanted cells, autophagy mai...