Supported by the National Natural Science Foundation of China (Grant Nos. 30470448 and 30130230);the National key Basic Research Program of China (Grant No. 2004CB720000);the Knowledge Innovative Program of The Chinese Academy of Sciences (Grant Nos. KSCX2-SW-224 and Y2004018);the Li Foundation and the Sinogerman Scientific Center
Insulin-responsive GLUT4(glucose transporter 4) translocation plays a major role in regulating glucose uptake in adipose tissue and muscle.Whether or not there is a specialized secretory GSV(GLUT4 storage vesicle) poo...
supported by the National Natural Science Foundation of China(30270363,30470448 and 30130230);the National High Technology Research and Development Program of China(2004CB720000).
Aim: To characterize Ca^2+-stimulated exocytosis in isolated mouse pancreatic β cells. Methods: An improved method was described for isolation of mouse pancreatic β cells by collagenase P. The Ca^2+ channel curr...
This work was supported by the grants from the National Natural Science Foundation of China (30025023, 3000062, 30130230 and 30370647);the Major State Basic Research Program of China (G1999054000 and 2004CB720000);the Chinese Academy of Sciences Project (KSCX2-SW-224);the National High Technology Research and Development Program of China (2002AA214061).
α-Latrotoxin from the venom of black widow spider induces and augments neurotransmitter and hormone release by way of extracellular Ca^2+ influx and cellular signal transduction pathways. By using whole cell current...