This work was supported by the National Basic Research Program of China (Grant Nos. 2009CB918404 and 2006CB910700), International S&T Cooperation Program of China (Grant No. 2007DFA31040) and the National Natural Science Foundation of China (Grant Nos. 30700154 and 31070746).
Dear Editor, Eukaryotic transcriptional regulation networks are extremely complex. Usually, multiple transcription factors (TFs) bind to the promoter region of a gene and cooperate to control gene expression precisely...
Background: The small nematode Caenorhabditis elegans (C.elegans) is an excellent model organism for studying the molecular and cellular basis of nervous system function. Since
Supported by National Key Basic Research and Development Program of China (Grant Nos. 2006CB0D1203, 2006CB0D1205 and 2006CB910700);National Natural Science Fundation of China (Grant No. 30800199)
What is the relationship between the topological connections among enzymes and their functions during metabolic network evolution? Does this relationship show similarity among closely related or-ganisms? Here we inves...