supported by Special Fund for Agroscientific Research in the Public Interest(201103007);a major project for Genetically Modified Organisms Breeding(2009ZX08009-075B);a key project from the National Natural Science Foundation of China(30330020);the National Natural Science Foundation of China(31070080);the Fundamental Research Funds for the Central Universities;funded by the China Postdoctoral Science Foundation(20090451464)
Deinococcus radiodurans possesses extreme resistance to ionizing radiation,and has been engineered for the remediation of toxic components in radioactive environments.We have previously shown that PprI(also named IrrE...
the National Basic Research Program (Grant No. 2004CB19604);National Hi-Tech Development Program (Grant No. 2007AA021305);Distinguished Young Scientist (Grant No. 30425038);key project from the National Natural Science Foundation of China (Grant No. 30330020)
Based on a genetically modified radioresistant bacteria Deinococcus radiodurans, we constructed a real time whole cell biosensor to monitor radioactivity and genotoxicity in highly radioactive environ-ment. The enhanc...
Supported by the National Program on Key Basic Research Projects (Grant No. 2004CB19604);National Natural Science Foundation of China (Grant Nos. 30425038 and 30330020)
The genome-wide transcription profile of Deinococcus radiodurans cells was investigated after treatment with low dose irradiation (2 kGy). From the expression profile, we found that the process of DNA repair was ind...
Supported by the National Basic Research Program of China (Grant No. 2004CB19604);National Science Fund for Distinguished Young Scholars (Grant No. 30425038);Key Project from the National Natural Science Foundation of China (Grant No. 30330020)
In eukaryotes, the Mre11-Rad50-Nbs1 (MRN) complex, which resides at the crossroads of DNA repair and checkpoint signaling, rapidly forms prominent foci at damage sites following double-strand break (DSB) induction. Th...
the National Basic Research Program of China (Grant No. 2004 CB 19604);Grant for Distinguished Young Scientist of China (Grant No. 30425038);National Natural Science Foundation of China (Grant No. 30330020)
The functional analysis of dr1127,a novel gene in Deinococcus radiodurans was performed in this pa-per. The dr1127 gene was found occasionally in our microarray and 2-DE gel experiments. Mutation of the dr1127 gene de...