supported by the Stem Cell and Translation National Key Project(2016ZY05002449);National Basic Research Program of China(2011CB965103,2012CBA01307);National Natural Science Foundation of China(81661130160,81422014,81561138004);Beijing Municipal Natural Science Foundation(5142005);Royal Society-Newton Advanced Fellowship(NA150482)
Oligodendrocyte progenitor cells(OPCs) hold great promise for treatment of dysmyelinating disorders, such as multiple sclerosis and cerebral palsy. Recent studies on generation of human OPCs mainly use human embryonic...
Repressor element 1-silencing transcription factor (REST) was recognized as a transcription suppressor regulating nervous system differentiation. However, the role of REST during early development has not been clari...