GASTRULATION

作品数:14被引量:32H指数:3
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相关领域:生物学更多>>
相关作者:王强楼宜嘉洪缨更多>>
相关机构:中国科学院浙江大学更多>>
相关期刊:《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《Science Bulletin》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Sex differences in human pre-gastrulation embryos
《Science China(Life Sciences)》2025年第2期397-415,共19页Yongjie Lu Meng Qin Xintong Qi Ming Yang Fan Zhai Jiaqi Zhang Zhiqiang Yan Liying Yan Jie Qiao Peng Yuan 
funded by grants from the National Key Research and Development Program(2019YFA0110001 and 2022YFC2702200);the National Natural Science Foundation of China(82288102,82125013,82201838,and 82101677);the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(YESS20200398)。
Human fetuses exhibit notable sex differences in growth rate and response to the intrauterine environment,yet their origins and underlying mechanisms remain uncertain.Here,we conduct a detailed investigation of sex di...
关键词:human embryo sex difference TROPHECTODERM primitive endoderm EPIBLAST 
Author Correction:Formative pluripotent stem cells show OPEN features of epiblast cells poised for gastrulation
《Cell Research》2022年第9期866-866,共1页
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License,which permits use,sharing,adaptation,distribution and reproduction in any medium or format,as long as you give approp...
关键词:Forma LICENSE FEATURES 
Formative pluripotent stem cells show features of epiblast cells poised for gastrulation被引量:6
《Cell Research》2021年第5期526-541,共16页Xiaoxiao Wang Yunlong Xiang Yang Yu Ran Wang Yu Zhang Qianhua Xu Hao Sun Zhen-Ao Zhao Xiangxiang Jiang Xiaoqing Wang Xukun Lu Dandan Qin Yujun Quan Jiaqi Zhang Ng Shyh-Chang Hongmei Wang Naihe Jing Wei Xie Lei Li 
The study was supported by the National Key R&D Program of China(2018YFC1004500,2017YFC1001401,2019YFA0508900);the National Natural Science Foundation of China(31930033,31590832,31988101,31725018).
The pluripotency of mammalian early and late epiblast could be recapitulated by naïve embryonic stem cells(ESCs)and primed epiblast stem cells(EpiSCs),respectively.However,these two states of pluripotency may not be s...
关键词:PLURIPOTENT FEATURES development. 
A developmental landscape of 3D-cultured human pre-gastrulation embryos
《Science Foundation in China》2020年第1期3-3,共1页
With the support by the National Natural Science Foundation of China,the research team led by Prof.Li TianQing(李天晴)at the Yunnan Key Laboratory of Primate Biomedical Research,Institute of Primate Translational Medi...
关键词:DEVELOPMENTAL HUMAN embryos 
Comments on ‘In vitro culture of cynomolgus monkey embryos beyond early gastrulation’被引量:1
《Journal of Molecular Cell Biology》2020年第5期400-402,共3页Huaixiao Ma Hongmei Wang Ping Zheng Lei Li 
National Key R&D Program of China(2018YFC1004500 ond 2017YFC1001401);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16020700);‘light of West China’Program of Chinese Academy of Sciences.
The fertilized egg undergoes several cleavage divisions to form the blastocyst in the oviduct.The blastocyst then is transferred to the uterus to initiate implantation,and trophectoderm-derived cells interact with the...
关键词:IMPLANTATION CULTURE BEYOND 
Prmt7 regulates epiboly and gastrulation ce movements by facilitating syntenin被引量:1
《Acta Biochimica et Biophysica Sinica》2018年第12期1280-1287,共8页Wuwen Zhang Yunbin Zhang Shifeng Li Zhili Wu Yuanchang Yan Yiping Li 
the grants from the National Natural Science Foundation of China (No.81571442);the Major State Basic Research Development Program of China (No.2011CB966301).
Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation.Despite of its fundamental function,little is known about the molecular mechanisms that control this coordinated cell movement....
关键词:EPIBOLY Print7 SYNTENIN MORPHOLINO CYTOSKELETON 
The genome-wide molecular regulation of mouse gastrulation embryo被引量:2
《Science China(Life Sciences)》2017年第4期363-369,共7页Guangdun Peng Naihe Jing 
supported by the “Strategic Priority Research Program” of the Chinese Academy of Sciences (XDA01010201);National Key Basic Research and Development Program of China (2014CB964804, 2015CB964500);National Natural Science Foundation of China (31430058, 31571513, 31630043, 91519314)
The diverse morphologies among vertebrate species stems from the evolution of a basic body plan that is constituted by a spatially organized ensemble of tissue lineage progenitors. At gastrulation, this body plan is e...
关键词:embryo morphogenetic spatially vertebrate diverse fertilization coordinated streak organized ensemble 
Apolipoprotein C1 regulates epiboly during gastrulation in zebrafish被引量:3
《Science China(Life Sciences)》2013年第11期975-984,共10页WANG Yang ZHOU Li LI Zhi LI WenHua GUI JianFang 
supported by grants from the National Basic Research Program of China(2010CB126300);the National High Technology Research and Development Program of China(2012AA092201-3);Ministry of Agriculture of China within the special Fund for Agro-scientific Research in the Public Interest(200903045);the National Natural Science Foundation of China(30971414)
Apolipoprotein C1 (Apocl) is associated with lipoprotein metabolism, but its physiological role during embryogenesis is largely unknown. We reveal a new function of Apoclb, a transcript isoform of Apocl, in epiboly ...
关键词:EPIBOLY apolipoprotein C1 E-cadherin radial intercalation 
Nodal Promotes mir206 Expression to Control Convergence and Extension Movements During Zebrafish Gastrulation被引量:2
《Journal of Genetics and Genomics》2013年第10期515-521,共7页Xiuli Liu Yuanqing Ma Congwei Zhang Shi Wei Yu Cao Qiang Wang 
supported by the grants from the Major Science Programs of China(Nos.2011CBA01101 and 2011CB943904);the National Natural Science Foundation of China(Nos.30971656 and 90919011)
Nodal, a member of the transforming growth factor β (TGF-β) superfamily, has been shown to play a role in mesendoderm induction and gastrulation movements. The activity of Nodal signaling can be modulated by micro...
关键词:NODAL mir206 Convergence and extension snailla E-CADHERIN 
NRSF/REST is required for gastrulation and neurogenesis during zebrafish development被引量:1
《Acta Biochimica et Biophysica Sinica》2012年第5期385-393,共9页Xuesong Wang Jianke Ren Zhugang Wang Jihua Yao Jian Fei 
Repressor element 1-silencing transcription factor (REST) was recognized as a transcription suppressor regulating nervous system differentiation. However, the role of REST during early development has not been clari...
关键词:NRSF/REST in situ hybridization MORPHOLINO matemal GASTRULATION NEUROGENESIS 
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