国家重点基础研究发展计划(2010CB126106)

作品数:25被引量:75H指数:7
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相关作者:李正名熊丽霞于淑晶孙丽娜芮昌辉更多>>
相关机构:南开大学中国农业科学院植物保护研究所中国海洋石油总公司天津医科大学更多>>
相关期刊:《农药学学报》《Chemical Research in Chinese Universities》《河北工业科技》《Chinese Journal of Chemistry》更多>>
相关主题:氯虫酰胺杀虫活性ACTIVITIES生物活性抑菌活性更多>>
相关领域:理学农业科学化学工程生物学更多>>
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Design,synthesis and insecticidal activities of novel anthranilic diamides containing fluorinated groups as potential ryanodine receptors activitors
《Chinese Chemical Letters》2017年第6期1248-1251,共4页Chang-Chun Wu Bao-Lei Wang Jing-Bo Liu Wei Wei Yu-Xin Li Yang Liu Ming-Gui Chen Li-Xia Xiong Na Yang Zheng-Ming Li 
financially supported by the National Natural Science Foundation of China(No.21372133);973 Program(No.2010CB126106);"111" Project of Ministry of Education of China(No.B06005)
In order to search for novel potent and environmentally benign insecticides,a series of anthranilic diamides containing various fluorinated groups were designed and synthesized.Their structures were confirmed by -1H N...
关键词:Anthranilic diamides Fluorinated moieties Insecticidal activities Structure-activity relationship Synthesis 
Design, Synthesis and Biological Activities of Novel Anthranilic Diamides Containing Dihydroisoxazoline and Isoxazole
《Chemical Research in Chinese Universities》2016年第1期41-48,共8页LIU Jingbo LI Yuxin CHEN Youwei WU Changchun WAN Yingying WEI Wei XIONG Lixia ZHANG Xiao YU Shujing LI Zhengming 
Supported by the National Basic Research Program of China(No.2010CB126106), the National Natural Science Foundation of China(Nos.21272129, 31370039), the National Key Technologies R&D Program of China(No.2011BAE06B05) and the "111" Project of the Ministry of the Education of China(No.B06005).
Anthranilic diamides are one of the most important classes of modern agrochemical insecticides. To discover new structures with higher activity, lower toxicity and lower residue, a series of novel anthranilic diamides...
关键词:Anthranilic diamide Dihydroisoxazoline ISOXAZOLE Biological activity Calcium channel 
新型含酰基脲桥和硫脲桥的苯双酰胺类似物的合成及生物活性被引量:1
《有机化学》2015年第4期882-889,共8页陈有为 万莹莹 刘巧霞 刘敬波 熊丽霞 于淑晶 李正名 
国家重点基础研究发展计划(973计划,No.2010CB126106);国家自然科学基金(Nos.31370039,21272129);国家科技攻关计划(No.2011BAE06B05);高等学校博士学科点专项科研基金(No.20110031110017)资助项目~~
参考氟虫酰胺和除虫脲的活性结构片段,设计合成了一系列结构新颖的含有酰基脲桥和酰基硫脲桥的化合物,通过核磁共振氢谱、高分辨质谱以及X射线单晶衍射确定了其结构.生测结果表明,酰基脲桥和酰基硫脲桥结构的引入使杀虫活性降低,但是化...
关键词:氟虫酰胺 除虫脲 酰基脲桥 硫脲桥 杀虫活性 抑菌活性 
含氟农药的研究进展被引量:6
《河北工业科技》2014年第3期262-270,共9页司伟杰 张涛 梅向东 张兰祥 董梦雅 张开心 宁君 
国家973计划项目(2010CB126106);国家科技支撑计划项目(2011BAE06B03)
近年来农药总的发展趋势是对靶标生物高效,对环境和非靶标生物安全。氟特殊的理化性质为其在农药中赢得了重要地位。在生物活性分子结构-活性的设计过程中引入氟,可以通过影响脂溶性、稳定性、渗透性中的任何一种性能来改变其生物活性;...
关键词:含氟农药 化学结构 生物活性 构效关系 研究进展 
Syntheses and Biological Activities of Novel 3-Bromo-1-(3-chloropy- ridin-2-yl)-N-hydroxy-N-aryl- 1H-pyrazole-5-carboxamides被引量:1
《Chemical Research in Chinese Universities》2014年第3期409-414,共6页ZHU Hongwei WANG Baolei ZHANG Xiulan XIONG Lixia YU Shujing LI Zhengming 
Supported by the National Basic Research Program of China(No.2010CB126106), the National Key Technologies Research and Development Program of China(No.2011BAE06B05-3) and the National Natural Science Foundation of China (No.21372133).
A series of novel 3-bromo-1-(3-chloropyridin-2-yl)-N-hydroxy-N-aryl-lH-pyrazole-5-carboxamides was synthesized by the reaction of pyrazole carbonyl chloride with each of substituted phenylhydroxyamines. The latter o...
关键词:N-Hydroxyl amide N-Pyridylpyrazole Insecticidal activity Fungicidal activity 
Synthesis and Biological Activities of Novel Methyl Xanthine Derivatives
《Chemical Research in Chinese Universities》2014年第1期98-102,共5页CHEN Youwei WANG Baolei GUO Yanjun ZHOU Yunyun PAN Li XIONG Lixia YU Shujing LI Zhengming 
Supported by the National Basic Research Program of China(No.2010CB126106), the National Natural Science Foundation of China(Nos.21272129, 21372133), the National Key Technologies Research and Development Program, China(No. 2011BAE06B05-3) and Specialized Research Fund for the Doctorial Program of Higher Education, China(No.20110031110017).
Caffeine is one of methyl xanthine compounds,which has the similar mode of action as ryanodine receptor insecticide.In order to find novel and efficient insecticide,structural modification of certain methyl xanthine c...
关键词:CAFFEINE XANTHINE Insecticidal activity Antifungal activity 
Synthesis and Biological Activity of Novel 1-Substituted Phenyl(glycosyl)-4-{4-[(4,6-dimethoxy)pyrimidin-2-yl] Piperazin-l-yl}methyl-lH-1,2,3-triazoles被引量:1
《Chemical Research in Chinese Universities》2013年第5期900-905,共6页MAO Ming-zhen LI Yu-xin ZHOU Yun-yun YANG Xiao-ping ZHANG Xiu-lan ZHANG Xiao LI Zheng-ming 
Supported by the National Basic Research Program of China(No.2010CB126106), the Fundamental Research Funds for the Central Universities and Natural Science Foundation of China(No.31000861).
A series of novel 1-substituted phenyl or glycosyl 1,2,3-triazoles was designed and synthesized by azide-alkyne 1,3-dipolar cyeloaddition between 4,6-dimethoxy-2-[(4-prop-2-ynyl)piperazin-l-yl]pyrimidine and each of...
关键词:1 H-1 2 3-Triazole Fungicidal activity Huisgen cycloaddition reaction Pyrimidinylpiperzine 
Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing 1,2,4-Triazolinone Moiety被引量:1
《Chemical Research in Chinese Universities》2013年第3期466-472,共7页LIU Zhuo PAN Li LIYong-hong WANG Su-hua LI Zheng-ming 
Supported by the National Basic Research Program of China(No.2010CB126106), the National Natural Science Foundation of China(No.21272129) and the National Key Technologies R&D Program, China(No.2011BAE06B05).
A series of new sulfonylureas incorporating 1,2,4-triazolinone moiety was synthesized, which were further bio-assayed for the herbicidal activity against four herbs, representative of monocotyledons and dicotyledons. ...
关键词:Sulfonylurea herbicide Acetohydroxyacid synthetase(AHAS) 1 2 4-Triazolinone derivative PROTOX Herbicidal activity 
含有单取代嘧啶的新型磺酰脲类化合物的设计、合成及除草活性被引量:9
《高等学校化学学报》2013年第6期1416-1422,共7页潘里 刘卓 陈有为 李永红 李正名 
国家自然科学基金(批准号:21272129);国家“九七三”计划项目(批准号:2010CB126106);国家科技攻关计划项目(批准号:2011BAE06B05)资助
为了寻找高效的磺酰脲类除草剂,以商品化磺酰脲类除草剂为基础,将单取代嘧啶结构引入到分子中,合成了一系列新型磺酰脲类化合物,并通过1H NMR和高分辨质谱确定了其结构.采用盆栽法和平皿法测试了所有化合物的除草活性以及部分化合物对...
关键词:磺酰脲 单取代嘧啶 除草活性 
Design, Synthesis and Structure-activity of N-Glycosyl-l-pyridyl-lH-pyrazole-5-carboxamide as Inhibitors of Calcium Channels
《Chemical Research in Chinese Universities》2013年第2期249-255,共7页ZHOU Yun-yun LI Yu-xin LI Yi-ming YANG Xiao-ping MAO Ming-zhen LI Zheng-ming 
Supported by the National Basic Research Program of China(No.2010CB126106), the National Natural Science Foundation of China(No.31000861), the Tianj in Natural Science Foundation, China(No. 11JCYBJC08600) and the National Key Technologies R&D Program of China(No.2011BAE06B05).
Carbohydrates, with broad-spectrum structures and biological functions, are key organic compounds in nature, along with nucleic acids and proteins. As part of our ongoing efforts to develop a new class of pesticides w...
关键词:N-Glycosyl PYRIDYL PYRAZOLE Insecticidal activity Calcium channel 
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