supported by the National Natural Science Foundation of China (30873010 and 81072220);the National High Technology Research and Development Program of China (2009AA02Z403)
DNAzymes(Dzs) are single-stranded DNA catalysts that specifically cleave the mRNA of targeted genes.Compared with other gene-silencing technologies,such as ribozymes,antisense oligonucleotide and small interference RN...
supported by the National High Technology Research and Development Program of China (2009AA02Z403);the National Natural Science Foundation of China (30873010 and 81072220)
Many human tumor cells are characterized by overexpression or mutation of epidermal growth factor receptor (EGFR). Emerging evidence indicates that EGFR, as well as some of its downstream components, can translocate t...
Supported by the National Natural Sciences Foundation of China(No.30873010);National High Technology R&D Program of China(No.2006AA02Z481;No.2009AA02Z403)
Signal transducers and activators of transcription-3(STAT3),a central cytoplasmic transcription factor,is frequently overexpressed and constitutively activated during malignant transformation.The overexpression of STA...