NUDE

作品数：185被引量：587H指数：14
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Semen features for conventional IVF: Need for a simple universal index
《Asian pacific Journal of Reproduction》2024年第2期49-51,共3页Mete Isikoglu 
Conventional in-vitro fertilization(C-IVF)and intracytoplasmic sperm injection(ICSI)are the two existing insemination methods presently in use in contemporary medically assisted reproduction treatments.While C-IVF ref...
关键词：injection NUDE ENOUGH 
Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β
《Signal Transduction and Targeted Therapy》2023年第12期5931-5943,共13页Hange Yang Xiaowei Zhang Cong Wang Hailong Zhang Juan Yi Kun Wang Yanzhe Hou Peihong Ji Xiaojie Jin Chenghao Li Min Zhang Shan Huang Haoyuan Jia Kuan Hu Lingyun Mou Rui Wang 
supported by the Program for the Ministry of Education“Peptide Drugs”Innovation Team(No.IRT_15R27,China);the National Natural Science Foundation of China(21807053);the CAMS Innovation Fund for Medical Sciences(CIFMS,Nos.2019-I2M-5-074,2021-I2M-1-026,2021-I2M-3-001,2022-I2M-2-002,China);the Fundamental Research Funds for the Central Universities(No.lzujbky-2023-11,lzujbky-2023-ct02,lzujbky-2023-it19,China).
The identification of effective drug targets and the development of bioactive molecules are areas of high need in cancer therapy.The phosphatidylinositol transfer protein alpha/beta isoform(PITPα/β)has been reported...
关键词：TUMOUR METABOLISM NUDE 
The protection of CoronaVac against the infection of wild-type SARS-CoV-2(WH-09)or Omicron variant in nude-hACE2 mice
《Animal Models and Experimental Medicine》2023年第4期346-354,共9页Kaili Lin Meixuan Liu Lu Sun Hanjun Fu Hongwei Qiao Shunyi Wang Sidan Pan Hong Gao 
the National Key Research and Development Project of China,Grant/Award Number:2020YFA0707600。
Background:Immunocompromised individuals have an increased risk of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection and severe outcomes,but we pay less attention to these people.Athymic nude mice a...
关键词：IMMUNOCOMPROMISED nude-hACE2 mice PROTECTION severe acute respiratory syndrome coronavirus 2 
建立适用于BALB/c Nude小鼠的急性肝衰竭模型
《中国组织工程研究》2023年第14期2152-2157,共6页谈佳音 刘阳 李斌 陆利 宋慧芳 
山西省自然科学研究面上项目(20210302123296),项目负责人:宋慧芳;山西省回国留学人员科研资助项目(2021-078),项目负责人:宋慧芳;中国博士后科学基金面上资助项目(2021M691994),项目负责人:宋慧芳。
背景:在干细胞和组织工程领域的动物实验中,免疫缺陷裸小鼠(BALB/c Nude小鼠)对于提升研究准确性具有重要意义。但CCl致BALB/c Nude小鼠发生急性肝衰竭的浓度及检测时间尚不明确,严重影响该动物模型在具有免疫原性的干细胞治疗研究中的...
关键词：四氯化碳 急性肝衰竭 BALB/c Nude小鼠 C57小鼠 模型 
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1被引量：15
《Signal Transduction and Targeted Therapy》2023年第3期1159-1174,共16页Heng Xu Hongfang Zhao Chunyong Ding Defang Jiang Zijie Zhao Yang Li Xiaoyu Ding Jing Gao Hu Zhou Cheng Luo Guoqiang Chen Ao Zhang Ying Xu Hao Zhang 
We are grateful to National Centre for Protein Science Shanghai for their instrument support and technical assistance.We thank the staffs from BL19U1 beamline of National Facility for Protein Science Shanghai(NFPS)at Shanghai Synchrotron Radiation Facility,for assistance during data collection.We gratefully acknowledge the financial supports from the National Key Research and Development Program of China(2020YFE0202200 to H.Z.and 2021ZD0203900 to C.L.);the project of National Multidisciplinary Innovation Team of Traditional Chinese Medicine(ZYYCXTD-202004 to C.L.);the National Natural Science Foundation of China(81903538 to H.Z.,82104064 to H.X.,91853205 to C.L.,91853206 to G.C.,81773565 to A.Z.,81972615 to Y.X.,and 21877120,22177068 to C.D.);the Postdoctoral Research Foundation of China(2019M661673 to H.Z.);the Shanghai Sailing Plan(19YF1457200 to H.Z.);the grants from Shanghai Jiao Tong University(AF1700037,WF220217002,WH101117001,and WF540162618 to A.Z.).
As a terpenoids natural product isolated from the plant Thunder God Vine,Celastrol is widely studied for its pharmacological activities,including anti-tumor activities.The clinical application of Celastrol is strictly...
关键词：COLORECTAL cancer NUDE 
Controlled fusion power is ittle nearer now than it was a week ago
《中国战略新兴产业》2023年第2期67-67,共1页
On December 13th Ameria's energy secretary,Jennifer Granholm,announced that the country's National Ignition Facility(NIF)had lived up to the“I”in its name,by achieving ignition.The stuff ignited was some pellets of ...
关键词：ADDITION stuff NUDE 
THE BUZZ
《城市漫步（GBA版）》2022年第4期8-9,共2页
RANDOM NUMBER 30...is the number of minutes it takes to get.a result using China's newtly devel-oped at-home testing kit for COVID-19.Prior to the kits becoming available,anyone who wanted to get a nudeic acid test fo...
关键词：NUDE TESTING BECOMING 
新时代设计教育中的融复合设计思维与方法——以Nude设计概念为中心
《浙江艺术职业学院学报》2022年第1期105-110,共6页何星池 
2019年度教育部人文社会科学研究青年基金项目(项目编号:19YJC760029);2021年度浙江省教育厅科研项目资助(项目编号:Y202146250);2021年度省属高校基本科研业务费项目(项目编号:GK219909299001-219)阶段性成果。
融合时代经济技术文化高速发展,面对不确定的市场需求,设计教育中需要结合设计师与策划师的两种互补性思维模式。因此,融复合设计思维区别于过去的线性流程思维登上了创意舞台。融复合设计思维的本质离不开分析性思维的前期驱动,更离不...
关键词：设计教育 融复合设计 设计思维 Nude设计 教学改革 
Novel lysosome-targeted anticancer fluorescent agents used in zebrafish and nude mouse tumour imaging被引量：2
《Frontiers of Chemical Science and Engineering》2022年第1期112-120,共9页Xiuli Chen Feng Liu Bin Chen Haiying Wu Kun Li Yongmei Xie Weihong Kuang Zhihui Li 
supported by Science and Technology Department of Sichuan Province(Nos.2020YJ0237,2018SZ0030,2019YFH0119);National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University(Z20191006);the 135 Project for Disciplines of Excellence,West China Hospital,Sichuan University(Nos.ZYJC18025 and ZYJC18003).
The design of three novel fatty nitrogen mustard-based anticancer agents with fluorophores incorporated into the alkene structure(CXL 118,CXL121,and CXL122)is described in this report.The results indicated that these ...
关键词：fluorescent drug LYSOSOMAL ANTICANCER ZEBRAFISH nude-mouse tumour imaging 
Single-cell characterization of monolayer cultured human dental pulp stem cells with enhanced differentiation capacity被引量：5
《International Journal of Oral Science》2021年第4期422-435,共14页Yu Cui Wei Ji Yongyan Gao Yao Xiao Huan Liu Zhi Chen 
This work was supported by grants from the National Natural Science Foundation of China(no.81771066)to Z.C.;from“the Fundamental Research Funds for the Central Universities”(no.2042021kf0197);the National Natural Science Foundation of China(no.81771057)to H.L.;from the Natural Science Foundation of Hubei Province(2020CFB618)to W.J.The numerical calculations in this paper have been done on the supercomputing system in the Supercomputing Center of Wuhan University.
Human dental pulp stem cells(hDPSCs)are easily obtained multipotent cells,however,their potential value in regenerative medicine is hindered by the phenotypic and functional changes after conventional monolayer expans...
关键词：NUDE PULP MONOLAYER 
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