《Oncology and Translational Medicine》

作品数:478被引量:277H指数:5
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《Oncology and Translational Medicine》
主办单位:华中科技大学同济医学院
最新期次:2025年1期更多>>
发文主题:CANCERPROGNOSISCASE_REPORTONCOLOGYBREAST_CANCER更多>>
发文领域:医药卫生自动化与计算机技术历史地理一般工业技术更多>>
发文基金:国家自然科学基金湖北省自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Pan-cancer transcriptomic analysis reveals HSPB8 as a prognostic and immunological biomarker in colorectal cancer
《Oncology and Translational Medicine》2025年第1期36-45,共10页Yuyong Deng Xuguang Sun Rui Jian DuojiaWu Junyang Wang Shan Li 
supported by the NationalNatural Science Foundation of China(no.32360888);the Jiangxi Students’Platform for Innovation and Entrepreneurship Training Program(no.202411843023).
Background:Heat shock protein B8(HSPB8)is implicated in autophagy,and its aberrant expression has been linked to both the ini-tiation and progression of tumors.However,the role and function of HSPB8 in colorectal canc...
关键词:BIOMARKER Differentially expressed gene HSPB8 Immune infiltration Pan-cancer 
Oncology and Translational Medicine Editorial Board
《Oncology and Translational Medicine》2025年第1期I0001-I0002,共2页
Advances in neoadjuvant therapy for resectable intrahepatic cholangiocarcinoma: An invited commentary
《Oncology and Translational Medicine》2025年第1期1-4,共4页Ruyu Han Peipei Song Wei Tang Tianqiang Song Lu Chen 
supported by the National Natural Science Foundation of China(grants 82373365 and 82173317);the Tianjin Key Medical Discipline Construction Project(TJYXZDXK-009A).
Intrahepatic cholangiocarcinoma(ICC)poses a significant threat to human health owing to its high malignancy rate and poor prognosis.Sur-gery is the most effective treatment option for ICC.However,the prognosis remains...
关键词:Intrahepatic cholangiocarcinoma Resectable Neoadjuvant therapy 
Perspectives on the potential application of microRNAs in the diagnosis and treatment of triple-negative breast cancer
《Oncology and Translational Medicine》2025年第1期5-9,共5页Yeqin Wu Haitao Song Huifang Shi Gangping Wang 
supported by Shandong Provincial Natural Science Foundation(no.ZR2020MH319).
Triple-negative breast cancer(TNBC)is currently the most heterogeneous and aggressive breast cancer type.It has a high recurrence rate,poor clinical prospects,and lack of predictive markers and potential treatment opt...
关键词:Triple-negative breast cancer MIRNA oncomiRs TUMORIGENESIS PROGNOSIS Chemotherapy resistance 
Advances in basic and translational research into nasopharyngeal carcinoma
《Oncology and Translational Medicine》2025年第1期10-16,共7页Zhe Li Yupei Chen Jun Ma 
supported by the National Natural Science Foundation of China(no.81930072 and no.82172870 to J.Ma);by the Key-Area Research and Development Program of Guangdong Province(no.2019B020230002 to J.Ma).
According to the International Cancer Research Institute of the World Health Organization data,nasopharyngeal carcinoma(NPC)remains a significant health concern,particularly in regions such as Southeast Asia and south...
关键词:Nasopharyngeal carcinoma Treatment resistance Tumor biomarkers Tumor microenvironment 
Advancements in conventional cancer therapy combined with immunotherapy
《Oncology and Translational Medicine》2025年第1期17-28,共12页Hongxia Li Songyan Han Chunbo Dong Zhida Liu 
supported by the National Science Foundation of China(No.82172726);the Youth Project of Science and Technology Department of Shanxi Province(No.202203021212105);the Research Project Supported by the Shanxi Scholarship Council of China(2021-156).
Conventional therapies are primary cancer treatments that directly eliminate or inhibit the growth of tumor cells,reducing the overall tumor burden.Increasing evidence suggests that conventional therapies possess sign...
关键词:Conventional therapy Tumor microenvironment IMMUNOTHERAPY Combinational therapy 
MiR-340-5p affects the proliferation and transfer of gastric cancer cells by targeting lncRNA HCG11 and NRF2 expression
《Oncology and Translational Medicine》2025年第1期29-35,共7页Rina Su Wei Luan Kai Zhang Shuai Liu Xiaoqing Zhang Yanwei Gao 
Funded by the general program of the Nature Fund of InnerMongolia Autonomous Region.
Objective:The aim of the study was to investigate the expression and biological role of nuclear factor erythroid–related factor 2(NRF2)in gastric cancer cells.Methods:Western blotting(WB)and reverse transcription-pol...
关键词:Gastric cancer Nuclear factor erythroid 2 related factor 2(NRF2) Apoptosis COX-2/PEG 2 signaling pathway 
Transformation of lung adenocarcinoma into small cell lung cancer after treatment with epidermal growth factor receptor tyrosine kinase inhibitors
《Oncology and Translational Medicine》2024年第6期286-291,共6页Linwu Kuang Yangkai Li 
Epidermal growth factor receptor tyrosine kinase inhibitors effectively improve the prognosis of patients with epidermal growth factor receptor–mutant lung adenocarcinoma.However,acquired resistance inevitably develo...
关键词:Small cell lung cancer transformation Lung adenocarcinoma EGFR-TKIS SCLC Drug resistance 
Exploring combination therapy centered on targeted immunotherapy for advanced hepatocellular carcinoma:a beacon of hope
《Oncology and Translational Medicine》2024年第6期292-299,共8页Yanbin Wang Yuqi Wu Hong Zhang Jing Wang Anping Song Hong Qiu Xianglin Yuan Hua Xiong Yanmei Zou 
Hepatocellular carcinoma(HCC)is an aggressive malignancy that is highly prevalent worldwide.It is often diagnosed at an advanced stage,which poses challenges for curative treatment and leads to an unfavorable prognosi...
关键词:Hepatocellular carcinoma Targeted immunotherapy Locoregional therapy Combination therapy 
Microvenular hemangioma located in the breast:a case report
《Oncology and Translational Medicine》2024年第6期300-303,共4页Mengting Dong Likun Zhang Jiayu Sheng Junyi Chen Ke Jiang 
supported by grants from the National Natural Science Foundation of China(no.82104952,no.82004240);Special Project for Clinical Research of Health Industry of Shanghai Municipal Health Commission(no.202140172);Special Project of Medical Innovation Research of Shanghai Science and Technology Commission(no.21Y11923600,no.23Y11921600);Yueyang Hospital of Integrated Traditional Chinese and Western Medicine of Translational Medicine Research Fund(no.2024YYZH05);Young Talents Training Project of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine(no.RY411.07.02.04).
Microvenular hemangioma(MVH)is a rare,benign type of hemangioma that typically presents as a solitary,slow-growing,red-to-violaceous asymptomatic papule,plaque,or nodule.It most commonly locations of the lesions on th...
关键词:Breast hemangioma HISTOPATHOLOGY IMMUNOHISTOCHEMISTRY Microvenous hemangioma MULTIPLE 
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