《Precision Clinical Medicine》

作品数：237被引量：285H指数：9
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《Precision Clinical Medicine》
主办单位：四川大学
最新期次：2024年4期更多>>
发文主题：PRECISIONMEDICINEJOURNALINSTRUCTIONSAUTHORS更多>>
发文领域：医药卫生文化科学自动化与计算机技术经济管理更多>>
发文基金：国家自然科学基金广东省自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Targeting ESM1 via SOX4 promotes the progression of infantile hemangioma through the PI3K/AKT signaling pathway
《Precision Clinical Medicine》2024年第4期283-298,共16页Yanan Li Meng Kong Tong Qiu Yi Ji 
supported by the National Natural Science Foundation of China(Grants No.82473553 and 82273556);the Key Project in the Science&Technology Program of Sichuan Province(Grants No.2022YFS0233 and 2022YFS0225);the Postdoctoral Foundation of West China Hospital of Sichuan University(Grant No.2023HXBH056);the Project of Natural Science Foundation of Shandong Province(Grant No.ZR2022MH229);the'O to 1'Project of Sichuan University(Grant No.2022SCUH0033);the Med-X Center for Informatics Funding Project(Grant No.YGJC004);the 1.3.5 Project for Disciplines of Excellence-Clinical Research Incubation Project of West China Hospital of Sichuan University(Grants No.2023HXFH004,2020HXFH048 and 2019HXFH056);the 1.3.5 Project for Disciplines of Excellence-Clinical Research Interdisciplinary Innovation Project of West China Hospital of Sichuan University(Grant No.ZYJC21060).
Background:Infantile hemangioma(IH)is the most prevalent benign vascular tumor in children,yet its pathogenesis remains incom-pletely understood.Research has established a strong association between sox4 and tumor blo...
关键词：infantile hemangioma CD31+HemECs SOX4 proliferation ANGIOGENESIS 
The relationship between contact lens ultraviolet light transmittance and myopia progression: a large-scale retrospective cohort study
《Precision Clinical Medicine》2024年第4期299-306,共8页Hiroyuki Okada Masao Yoshida Masaki Takeuchi Eichi Okada Nobuhisa Mizuki 
study followed the tenets of the Declaration of Helsinki and was approved by Yokohama City University Ethics Committee(2023-022).
Background:The prevalence of myopia is increasing dramatically around the world,and many studies have suggested the possibility that ultraviolet(Uv)light is effective to prevent the onset and progression of myopia.How...
关键词：ULTRAVIOLET MYOPIA PROGRESSION cohort study contact lens onhicalAhetract 
Application of metagenomic next-generation sequencing with brain tissue biopsy for diagnosing intracranial lesions in people with HIV
《Precision Clinical Medicine》2024年第4期360-364,共5页Ye Xiong Dairong Xiang Xiaotang Zhou Ying Huang Jean-Pierre Routy Biao Zhu 
supported by grants from the National Key R&D Program of China(Grants No.2022YFC2305202,2021YFC2301900-2021YFC2301901)。
Dear Editor,The central nervous system(CNS)is a target of the human immunodeficiency virus(HIV)[1].Late presenters with advanced HIV infection may develop opportunistic cerebral infections or lymphoma,most often Epste...
关键词：diagnosis CEREBRAL LESIONS HIV 
Revisiting ecological fallacy: are single-case experimental study designs even more relevant in the era of precision medicine?
《Precision Clinical Medicine》2024年第4期365-366,共2页Theodoros Christophidess Maria Karekla 
Dear Editor,"Give different ones[liquid medicines]to different patients,for the sweet ones do not benefit everyone,nor do the astringent ones,nor all the patients able to drink the same things"-Hippocrates(Diseases Ⅲ...
关键词：EVERYONE MEDICINE visiting 
Global distribution of Klebsiella pneumoniae producing extended-spectrum β-lactamases in neonates
《Precision Clinical Medicine》2024年第4期367-369,共3页Ya Hu Yu Feng Zhiyong Zong 
supported by the National Key Research and Development Program of China(Grant No.2023YFC2308800);the Natural Science Foundation of Sichuan Province(Grant No.2023NSFSC1697);the 1.3.5 Project for Disciplines of Excellence,West China Hospital of Sichuan University(Grant No.ZYGD22001).
DearEditor,Klebsiella pneumoniae,a member of the Enterobacterales,is a common resident of the gastrointestinal tract of humans and animals and is also ubiquitous in the environment.Klebsiella pneumoniae is also a comm...
关键词：LACTAMASE SPECTRUM CLINICAL 
Instructions to Authors
《Precision Clinical Medicine》2024年第4期I0002-I0003,共2页
Introduction Submission/How to contact the editorial office All manuscripts are submitted and reviewed via the journal's web-based manuscript submission system:http://mc.manuscriptcentral.com/pcm.New authors should cr...
关键词：JOURNAL submit EDITORIAL 
Targeted nuclear degranulation of neutrophils promotes the progression of pneumonia in ulcerative colitis
《Precision Clinical Medicine》2024年第4期307-317,共11页Yiming Shao Qibing Zheng Xiaobei Zhang Ping Li Xingxin Gao Liming Zhang Jiahong Xu Lingchao Meng Yanyun Tian Qinqin Zhang Guangxi Zhou 
supported by grants from the National Natural Science Foundation of China(Grants No.82270562,82302800);China Postdoctoral Science Foundation(Grant No.2024M751108);Tai Shan Young Scholar Foundation of Shandong Province(Grant No.tsqn202103190);Postdoctoral Fund of The Affiliated Hospital of Jining Medical University(Grant No.JYFY364862);Postdoctoral Innovation Program in Shandong Province(Grant No.SDCX-ZG-202400032);Doctor Fund of The Affiliated Hospital of Jining Medical University(Grant No.2022-BS-07)。
Background:Both intestinal and pulmonary systems are parts of the mucosal immune system,comprising~80%of all immune cells.These immune cells migrate or are transported between various mucosal tissues to maintain tissu...
关键词：NEUTROPHILS targeted nuclear degranulation reverse migration ulcerative colitis PNEUMONIA 
Comparative analysis of tertiary lymphoid structures for predicting survival of colorectal cancer: a whole-slide images-based study
《Precision Clinical Medicine》2024年第4期318-328,共11页Ming He Huifen Ye Liu Liu Su Yao Zhenhui Li Xinjuan Fan Lili Feng Tong Tong Yanfen Cui Xiaotang Yang Xiaomei Wu Yun Mao Ke Zhao Zaiyi Liu 
supported by the National Science Fund for Distinguished Young Scholars of China(Grant No.81925023);Joint Funds of the National Natural Science Foundation of China(Grant No.U23A20478);the National Science Foundation for Young Scientists of China(Grant No.82202267,82101996).
Background:Tertiary lymphoid structures(TLS)are major components in the immune microenvironment,correlating with a favorable prognosis in colorectal cancer.However,the methods used to define and characterize TLS were ...
关键词：colorectal cancer tertiary lymphoid structures digital pathology prognosis immune 
Novel immunotherapeutic approaches in gastric cancer
《Precision Clinical Medicine》2024年第4期329-353,共25页Meng Yang Wuhao Lin Jiaqian Huang Alessandro Mannucci Huiyan Luo 
supported by the National Key Research and Development Program of China(Grant No.2021YFF1201300);the National Natural Science Foundation of China(Grants No.82273402,92374114,and 81930065);the Science and Technology Program of Guangdong(Grant No.2019B020227002);the Natural Science Foundation of Guangdong Province(Grant No.2014A030312015);the Science and Technology Program of Guangzhou(Grants No.202002030208,201904020046,and 2019B020227002);Guangzhou Key Research and Development Project(Grant No.202206080008);Guangdong Special Support Plan(Grant No.2023TX07Y430).
Gastric cancer is a malignant tumor that ranks third in cancer-related deaths worldwide.Early-stage gastric cancer can often be ef-fectively managed through surgical resection.However,the majority of cases are diagnos...
关键词：gastric cancer IMMUNOTHERAPY immune checkpoint inhibitor adoptive cell therapy CAR-T 
Melatonin as a potential adjunct therapy for central nervous system lupus: evidence from the MRL/lpr mouse model
《Precision Clinical Medicine》2024年第4期354-356,共3页Jaivarshaan Rajkumar Alexandra Spath Hyndevi Dokuri Alexander Jacob Richard John Quigg Jessy John Alexander 
supported by the National Institutes of Health(Grant No.1R01DK111222,to JJ.A.);the Dr Arthur M.Morris endowment(to R.J.Q.).
Dear Editor,Systemic lupus erythematosus(SLE)is a multifaceted autoimmune disorder that affects over a million Americans,predominantly women,with a female-to-male ratio of~9:1 and higher prevalence rates in African-Am...
关键词：LUPUS SPITE carry 
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