The molecular classification of breast cancer plays a pivotal role in developing personalized treatment strategies,with the aim of improving therapeutic outcomes.Despite significant advancements,current diagnostic wor...
Metabolic reprogramming is an intrinsic characteristic of cancer,contributing to its establishment and progression,survival,high proliferation rates,and increased migratory and invasive potential;tumor cells establish...
supported by the National Natural Science Foundation of China(No.82304971,No.82004122);the Natural Science Foundation of Shandong Province(No.ZR2023QH194);Special Foundation for Taishan Scholars(No.ts20190971);Foundation from Clinical Research Center of Shandong University(No.2020SDUCRCA015).
The tumor microenvironment(TME)of breast cancer(BC)is depicted as an immunosuppressive dwelling that comprises a myriad of cell types embedded in the extracellular matrix.As one of the most abundant cell populations w...
supported by Shenzhen Science and Technology Innovation Commission(JCYJ20220530150412026);Guangdong Basic and Applied Basic Research Foundation(2023A1515111112);Shenzhen Clinical Medical Research Center for Urology and Nephrology。
Hypertension is a known risk factor for clear cell renal cell carcinoma(ccRCC),yet the underlying mechanisms remain elusive.Studies have confirmed that the renin-angiotensin system(RAS)plays a role beyond regulating b...
Aim:The purpose of this study is to enhance the understanding of bladder cancer and the role of cancer-associated fibroblasts(CAFs)in its progression.We aim to identify CAF-specific biomarkers and develop a prognostic...
Molecular bases of disease dissemination in lymphoid malignancies to optimize curative therapeutic strategies(51000 No.21198),Associazione Italiana per la Ricerca sul Cancro Foundation Milan,Italy;PNRR-MAD-2022-12375673(Next Generation EU,M6/C2_CALL 2022),Italian MoH,Rome,Italy;the AGING Project(Department of Excellence),DIMET,Universitàdel Piemonte Orientale,Novara,Italy.
Aim:The aim of the current study was to evaluate the potential clinical impact of clonal evolution detected by fluorescence in situ hybridization(FISH)in untreated chronic lymphocytic leukaemia(CLL)patients managed wi...
Esophageal cancer is a highly lethal cancer with notable global variations in incidence and risk factors.In the U.S.,it ranks as the fifth most common gastrointestinal cancer,with around 16,940 new cases annually,whil...
In Italy,a nationwide population-based colorectal cancer(CRC)screening initiative has been in place since 2006.In recent years,there has been a growing interest in involving community pharmacies in this activity.This ...
Aim:Cancer as a complex disease poses significant challenges for both diagnosis and treatment.Researchers have been exploring various avenues to find effective therapeutic strategies,with a particular emphasis on cell...
This insightful interview article covers the Journal of Cancer Metastasis and Treatment’s special interview with Dr.William C.Cho,focusing on his career trajectory,research focus,and ambitious goals for the next five...