《Pediatric Investigation》

作品数：399被引量：478H指数：9
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《Pediatric Investigation》
主办单位：Chinese Medical Association
最新期次：2024年4期更多>>
发文主题：PEDIATRICCHILDRENINFANTCENTERIN_CHINA更多>>
发文领域：医药卫生文化科学自动化与计算机技术哲学宗教更多>>
发文基金：国家自然科学基金北京市自然科学基金World Health Organization国家重点基础研究发展计划更多>>
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Novel compound heterozygous variants in the TSPEAR gene causing autosomal recessive hearing loss in a Chinese family
《Pediatric Investigation》2024年第4期313-315,共3页Xinyu Shi Xiaozhou Liu Zhengdong Zhao Yanjun Zong Yu Sun 
funded by the Innovative Research Groups of Hubei Province(No.2023AFA038);the National Key Research and Development Program of China(No.2021YFF0702303,2023YFE0203200);the National Natural Science Foundation of China(No.82071058)
To the editor:Hearing loss is the most common sensory disorder.TSPEAR gene encodes thrombospondin-type laminin G domain and epilepsy-associated repeats containing protein.1 While,patients with variants in the TSPEAR g...
关键词：Chinese family VARIANT sensory disordertspear gene clinical phenotypesincluding TSPEAR gene congenital sensorineural hearing loss autosomal recessive hearing loss tspear gene 
Real-world use of emicizumab in Chinese children with hemophilia A:Retrospective data from a comprehensive care center
《Pediatric Investigation》2024年第4期244-252,共9页Qianqian Mao Zhenping Chen Guoqing Liu Gang Li Yingzi Zhen Xiaoling Cheng Zekun Li Wanru Yao Di Ai Zhengping Li Nan Wang Man-Chiu Poon Runhui Wu 
National Natural Science Foundation of China,Grant/Award Number:82270133
Importance:Emicizumab(EMI)is efficacious and safe for hemophilia A(HA)prophylaxis.However,its high cost poses a challenge in China.Objective:To explore the possibility of using reduced-dosage EMI in Chinese HA childre...
关键词：Hemophilia A Emicizumab PROPHYLAXIS 
Clinical evaluation of bispectral index-guided closed-loop infusion of propofol for preschool children:A multi-center randomized controlled study
《Pediatric Investigation》2024年第4期271-277,共7页Lei Hua Bin Du Yunxia Zuo Huacheng Liu Jianmin Zhang 
Importance:The closed-loop infusion system can automatically adjust and maintain the depth of anesthesia by using the propofol target-controlled infusion(TCI)model under the feedback guidance of the bispectral index(B...
关键词：CLOSED-LOOP Target-controlled infusion Bispectral index Preschool children 
Research progress of microvascular development in bronchopulmonary dysplasia
《Pediatric Investigation》2024年第4期299-312,共14页Jiaxin Zhang Weiwei Du Zongli Zhang Tao Li Xingchao Li Shibing Xi 
Hubei Provincial Natural Science Foundation of China,Grant/Award Number:2021CFB270;Innovative Research Program for Graduates of Hubei University of Medicine,Grant/Award Number:YC2022035;Scientific and Technological Project of Shiyan City of Hubei Province,Grant/Award Number:21Y32
Bronchopulmonary dysplasia(BPD)is a chronic lung disease that arises during the neonatal period,and its underlying mechanisms are still not fully understood.The disorder of microvascular development plays a significan...
关键词：Bronchopulmonary dysplasia MICROVASCULAR THERAPY 
Etanercept:A viable treatment option for young children with generalized pustular psoriasis
《Pediatric Investigation》2024年第4期295-298,共4页Yunliu Chen Zhaoyang Wang Chaoyang Miao Zigang Xu Xin Xiang 
National Key R&D Program of China,Grant/Award Number:2023YFC2508101;Beijing Hospitals Authority’s Ascent Plan,Grant/Award Number:DFI20241201
Generalized pustular psoriasis(GPP)is a severe inflammatory cutaneous disease characterized by widespread pustules,edema,erythema,fever,and systemic inflammation.Chinese data indicate that the prevalence and incidence...
关键词：severe inflammatory cutaneous disease generalized pustular psoriasis TNF children ETANERCEPT generalized pustular psoriasis gpp IL activating nuclear f 
A neonate in emergency for giant auricular and cervical lymphatic malformations:Ultrasound-guided percutaneous bleomycin sclerotherapy may be a choice
《Pediatric Investigation》2024年第4期316-318,共3页Jiaojiao Ding Mingyan Hei Wenjia Cai Wenyuan Shi Xin Ni 
To the editor:Lymphatic malformations(LMs)are benign anomalies often detected at birth,with an incidence of 1.2–2.8 per 1000 newborns.1 While most early-life LMs are asymptomatic and may only require observation,some...
关键词：ultrasound guided percutaneous bleomycin sclerotherapy cervical lymphatic malformations emergency significant cosmetic deformities NEONATE giant auricular 
International outbreak of acute pediatric hepatitis:Was acetaminophen the missing link?
《Pediatric Investigation》2024年第4期241-243,共3页Stephen A.Hoption Cann 
During the outbreak of acute pediatric hepatitis,two centers reported a threefold increase in cases.1 In their report,the hepatitis was preceded by an acute viral infection with a period of fasting.Patients ranged in ...
关键词：ACETAMINOPHEN acute viral infection viral infection OUTBREAK FASTING acute pediatric hepatitis 
Comparative analysis of formulae for umbilical venous catheterization depth based on birth weight
《Pediatric Investigation》2024年第4期265-270,共6页Jingjie Luo Xu Zheng Zixin Yang Keyue Li Lu Chen Mingyan Hei 
Capital’s Funds for Health Improvement and Research,Grant/Award Number:#2022-2-2095
Importance:Umbilical venous catheterization(UVC)is a common procedure for critically ill newborn infants.The insertion depth was estimated before the procedure using various formulae.Objective:To compare the accuracy ...
关键词：ACCURACY DEPTH INFANT NEWBORN Umbilical vein catheterization 
Design and implementation of a multicenter protocol to obtain impulse oscillometry data in preterm children
《Pediatric Investigation》2024年第4期253-264,共12页Katharine Tsukahara Clement L.Ren Julian Allen Carla Bann Joseph McDonough Kristina Ziolkowski Charles C.Clem Sara B.DeMauro 
National Heart,Lung,and Blood Institute,Grant/Award Numbers:U24HL137729,U24HL143216,UG3HL143204,UH3HL137872,UH3HL137872-04S1;Eunice Kennedy Shriver National Institute of Child Health and Human Development,Grant/Award Numbers:UG1HD21373,UG1HD27853,UG1HD27856,UG1HD36790,UG1HD68244,UG1HD68284,UG1HD68244;Children’s Hospital of Philadelphia,Grant/Award Number:Morse Asthma Research Fund;The Capek Foundation;National Human Genome Research Institute,Grant/Award Number:T32 HG009495
Importance:Objective measures of lung function are critical for assessing respiratory outcomes of prematurity.Among extremely low gestational age neonates(ELGANs)(<29 weeks gestational age),high rates of neurodevelopm...
关键词：Bronchopulmonary dysplasia Extremely low gestational age neonates Extremely preterm infants OSCILLOMETRY Pulmonary function tests 
Utilizing mesenteric near-infrared reflectance spectroscopy to predict gastrointestinal complication risks and optimize feeding strategies in infants undergoing cardiac surgery
《Pediatric Investigation》2024年第4期287-294,共8页Wenpeng Xie Yinan Liu Yating Zeng Yirong Zheng Qiang Chen 
Importance: Gastrointestinal complications are common perioperative complications in children with congenital heart disease (CHD), and as near-infrared reflectance spectroscopy (NIRS) provides a non-invasive, real-tim...
关键词：Congenital cardiac disease Mesenteric NIRS Gastrointestinal complications Initial feeding 
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