funded by grants from the British Journal of Anaesthesia,London,UK and the European Society of Anesthesiology and Intensive Care,Brussels,Belgium.
Coronavirus disease 2019(COVID-19)has caused>760 million SARS-CoV-2 infections and 6.9 million deaths globally as reported by the World Health Organization(WHO).The virus is predominately a respiratory virus,but it ha...
Shanghai Directed Projects of Biopharmaceutical Field(22DX1900600)Shanghai Research Center for Burn and Wound Repair(2023ZZ02013);Shanghai Municipal Key Clinical Specialty of China(shslczdzk02302).
Burns are a main cause of accidental injuries among children in China.Because of the unique wound repair capacity and demand for growth in pediatric patients,the management of pediatric deep partial-thickness burn wou...
funded by the National Natural Science Foundation of China(No.82172202);the Innovative Leading Talents Project of Chongqing,China(No.cstc2022ycjh-bgzxm0148).
Background:The gut microbiota is a complex ecosystem that plays a critical role in human health and disease.However,the relationship between gut microbiota and intestinal damage caused by burns is not well understood....
supported by the National Key R&D Program of China(2022YFA1105900);the National Natural Science Foundation of China(81701127);the Nantong Science and Technology Foundation of China(JC2021058);the Large Instruments Open Foundation of Nantong University(KFJN2231,KFJN2275).
Spinal cord injury(SCI)is an incurable trauma that frequently results in partial or complete loss of motor and sensory function.Massive neurons are damaged after the initial mechanical insult.Secondary injuries,which ...
supported by grants from the National Natural Sciences Foundation of China(Nos.81730057,82130062,81801935);Key Project of Military Medical Innovation Program of Chinese PLA(Nos.18CXZ025,18CXZ026);Provincial Key Project of Medical Science Research of Hebei(20210013).
Background:Ribophagy is a selective autophagic process that specifically degrades dysfunctional or superfluous ribosomes to maintain cellular homeostasis.Whether ribophagy can ameliorate the immunosuppression in sepsi...
supported by grants from National Natural Science Foundation of China(82002036).
Background:Respiratory and circulatory dysfunction are common complications and the leading causes of death among burn patients,especially in severe burns and inhalation injury.Recently,extracorporeal membrane oxygena...
supported by grants from the National Natural Sciences Foundation of China(No.81901961 to TFL,No.81630055 andNo.81920108022 to GXL,No.31872742 to WFH);the Military Medical Science and Technology Youth Training Program of the Army Military Medical University(Third Military Medical University)(No.20QNPY024 to WFH);the Special Project for Enhancing Science and Technology Innovation Ability(frontier exploration)of the Army Military Medical University(Third Military Medical University)(No.2019XQY12 to WFH).
The immune microenvironment plays a critical role in regulating skin wound healing.Macrophages,the main component of infiltrating inflammatory cells,play a pivotal role in shaping the immune microenvironment in the pr...
Background:Biomaterials are vital products used in clinical sectors as alternatives to several biological macromolecules for tissue engineering techniques owing to their numerous beneficial properties,including wound ...
supported partly by grants from the National Natural Science Foundation of China(81720108008,82090024);the National Key R&D Program of China(2020YFC2005000).
Acute kidney injury(AKI)is a major renal disease characterized by a sudden decrease in kidney function.After AKI,the kidney has the ability to repair,but if the initial injury is severe the repair may be incomplete or...
funding by the National Natural Science Foundation of China(No.81871817,No.82202770,No.81802205);the Natural Science Foundation of Chongqing(No.CSTB2022NSCQMSX1267,No.CSTB2022NSCQ-MSX0863);the Laboratory Project of State Key Laboratory of Trauma,Burn and Combined Injury(No.SKL2021JY01);the Military Project of PLA(No.2020XYY11,No.21WQ002,No.2019HQZX03).
Autophagy,as a fundamental mechanism for cellular homeostasis,is generally involved in the occurrence and progression of various diseases.Osteoarthritis(OA)is the most common muscu-loskeletal disease that often leads ...