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作品数:23127被引量:47438H指数:44
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相关机构:温州中胤鞋服有限公司中国科学院温州中胤设计有限公司浙江大学更多>>
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Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease
《Neural Regeneration Research》2025年第10期2998-3012,共15页Yuan Zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng Yang 
supported by the Science and Technology(S&T)Program of Hebei Province,No.22377798D(to YZ).
Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease progression.The proteins,DNA,mRNA,and lipids carried by exosomes reflect...
关键词:biomarker diagnosis EXOSOMES N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein 
Exploring the role of N-acetyltransferases in diseases:a focus on N-acetyltransferase 9 in neurodegeneration
《Neural Regeneration Research》2025年第10期2862-2871,共10页Prajakta Deshpande Anuradha Venkatakrishnan Chimata Amit Singh 
supported by 1RO1EY032959-01 and RO1 supplement from NIH,Schuellein Chair Endowment Fund and STEM Catalyst Grant from the University of Dayton(to AS).
Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivo...
关键词:acetyl-coenzyme A Alzheimer’s disease animal models cell death DROSOPHILA eye human disease c-Jun N-terminal kinase signaling N-Acetyltransferases N-acetyltransferase 9 NEURODEGENERATION 
Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage
《Neural Regeneration Research》2025年第9期2454-2463,共10页Victoria Jiménez Carretero IrisÁlvarez-Merz Jorge Hernández-Campano Sergei A.Kirov Jesús M.Hernández-Guijo 
supported by MICIU(grant number PID2021-128133NB-100/AEI/FEDER10.13039/501100011033 to JMHG);by the National Institutes of Health(grant number R01 NS083858 to SAK);the Intramural Grants Program IGPP00057(to SAK);VIC enjoys a FPU contract from the Comunidad de Madrid(PIPF-2022/SAL-GL-25948)。
The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is well-documented.Nevertheless,the role of non-excitatory amino acids in brain damage following a stroke ...
关键词:cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids STROKE synaptic transmission 
Keemun black tea stems and leaves:comparison of chemical characterization and anti-inflammatory activities
《Food Science and Human Wellness》2025年第4期1546-1556,共11页Mengting Zhu Xiaoqing Rong Mingchun Wen Piaopiao Long Zongde Jiang Wen Xu Daniel Granato Liang Zhang 
supported by the Natural Science Foundation of China(32122079,32072633);Earmarked Fund for China Agriculture Research System(CARS-19);Anhui Key Research and Development Plan(202104b11020001);Young Elite Scientist Sponsorship Program by National CAST(2016QNRC001);High-level Introduced Talent Sponsorship Program by Anhui Agricultural University(rc352203)。
This work aims to compare the chemical composition and anti-inflammatory effects on RAW264.7 macrophages of Keemun black tea stems and leaves.A total of 50 volatile compounds were identified in tea stems and leaves,an...
关键词:Black tea stems Volatile compounds Non-volatile compounds Anti-inflammatory activities CYTOKINES 
Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke
《Neural Regeneration Research》2025年第7期2015-2028,共14页Jian Yang Jiang Wu Xueshun Xie Pengfei Xia Jinxin Lu Jiale Liu Lei Bai Xiang Li Zhengquan Yu Haiying Li 
supported by the National Natural Science Foundation of China,Nos.82071307(to HL),82271362(to HL),82171294(to JW),82371303(to JW),and 82301460(to PX);the Natural Science Foundation of Jiangsu Province,No.BK20211552(to HL);Suzhou Medical Technology Innovation Project-Clinical Frontier,No.SKY2022002(to ZY);the Science and Education Foundation for Health of Suzhou for Youth,No.KJXW2023001(to XL)。
Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to remyelination.Failure of remyelination due to oligodendrocyte progenitor cell death can result in severe n...
关键词:BIOINFORMATICS bulk RNA sequencing ferroptosis ischemic stroke myelin injury oligodendrocyte progenitor cell perilipin-2 single-cell RNA sequencing 
基于主题条件CNN-BiLSTM的旋律自动生成方法
《河南师范大学学报(自然科学版)》2025年第3期135-142,共8页曹西征 张航 李伟 
国家自然科学基金(U1604154);河南省重点科技攻关项目(252102211035).
为了有效地生成结构化的旋律,提出了一种基于主题条件CNN-BiLSTM的旋律自动生成方法.将旋律表示为钢琴卷帘窗的形式,使用定长、变长相结合的方法分割钢琴卷帘窗;通过Ward聚类算法对钢琴卷帘窗片段进行聚类分析,将获取的最大簇作为歌曲...
关键词:音乐生成 自动作曲 CNN-BiLSTM 旋律主题提取 聚类 
Modern aspects of diagnosing purulent pathology of the ear(Review of cases of middle ear cholesteatoma using non-EPI DWI MRI)
《Journal of Otology》2025年第2期117-122,共6页Asel Imangalieva Dina Kussainova Otabek Tajibaev Segizbayeva Aliya 
Chronic suppurative otitis media(CSOM)is a prevalent condition in otolaryngology with significant medical and social implications,including hearing loss and severe intracranial complications.This article discusses the...
关键词:CHOLESTEATOMA MRI non-EPI DWI chronic otitis media 
MoS_(2)/Ni_(3)S_(2)@N-rGO异质结纳米片阵列的制备及电催化性能研究
《吉林师范大学学报(自然科学版)》2025年第2期40-47,共8页曹健 金豆豆 董朝旭 张鹤馨 
国家自然科学基金项目(22378158)。
利用两步水热法在泡沫镍上原位生长氮掺杂还原氧化石墨烯负载的MoS_(2)/Ni_(3)S_(2)异质结构(MNG).优化后的MNG 0.5在碱性溶液中表现出优异的HER、OER活性和稳定性(40 h).在10 mA/cm^(2)的电流密度下,HER过电势为100 mV;在50 mA/cm^(2)...
关键词:N-rGO MoS_(2)/Ni_(3)S_(2) 电催化 
基于改进的Halpin-Tsai模型对纤维增强复合材料弹性常数预测
《广西科技大学学报》2025年第2期8-17,共10页武顺心 朱水文 
湖北省教育厅项目(B2023076);湖北汽车工业学院博士基金项目(BK202213);湖北省汽车传动与电子控制重点实验室开放基金项目(ZDK12023B09)资助。
为预测不同截面形状对复合材料弹性常数的影响,以碳纤维增强环氧树脂为例,采用细观复合材料力学方法,建立纤维复合材料的代表性体积单元(random volume element,RVE)模型,研究纤维截面形状和纤维的体积分数对其弹性常数的影响,通过改进...
关键词:Halpin-Tsai模型 横截面形状 弹性模量 代表性体积单元(RVE) 体积分数 
Large Deviations for a Critical Galton-Watson Branching Process
《Acta Mathematicae Applicatae Sinica》2025年第2期456-478,共23页Dou-dou LI Wan-lin SHI Mei ZHANG 
supported by the National Natural Science Foundation of China(No.12101023,No.11871103 and 12271043);the National Key Research and Development Program of China(No.2020YFA0712900);Fundamental Research Funds for the Central Universities(No.2023MS077)).
In this paper,a critical Galton-Watson branching process {Z_(n)} is considered.Large deviation rates of SZ_(n):=Σ_(i=1)^_(Z_(n)) Xi are obtained,where {X_(i);i≥1} is a sequence of independent and identically distrib...
关键词:large deviation branching process CRITICAL α-stable 
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