云南高校图书馆联盟文献共享服务平台- GYPENOSIDES

GYPENOSIDES: 作品数：15被引量：51H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：陈小义谢文利李积胜张莉齐刚更多>>; 相关机构：武警医学院湖北医药学院辽宁省血栓病中西医结合医疗中心更多>>; 相关期刊：《Chinese Herbal Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》《World Journal of Gastroenterology》更多>>; 相关基金：国家自然科学基金湖北省卫生厅科研基金国家重点基础研究发展计划更多>>

Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway: 《Genes & Diseases》2024年第3期120-123,共4页Hui Wang Zhonghao Li Qisheng Wang Weixin Lin Ziting Zhou Xinru Mu Yongwei Jiang Shengfeng Lu Shaodong Chen Zhigang Lu; supported by the National Natural Science Foundation of China(No.82174498,82174141);the National Administration of Traditional Chinese Medicine Youth Qihuang Scholars Support Project,the Open Project of Chinese Materia Medica First-Class Discipline of Nanjing University of Chinese Medicine(China)(No.2020YLXK013);the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(No.KYCX21_1796).; Opioid abuse can suppress the lymphatic system function,and produce severe immunosuppression that poses a significant risk of opportunistic infections such as methicillinresistant Staphylococcus aureus(MRSA)pneumonia....; 关键词：HERBAL GYPENOSIDES IMMUNOSUPPRESSION

Gypenosides improve liver lipid deposition in ApoE^(-/-) AS mice by inhibiting the Bcl2L12 apoptosis pathway: 《China Medical Abstracts(Internal Medicine)》2024年第1期12-12,共1页赵卓; Objective To explore the mechanism of gypenosides(GPs) preventing and treating atherosclerosis (AS)through Bcl2L12-mediated apoptosis pathway.Methods ApoE^(-/-) mice were selected and randomly divided into model group...; 关键词：C57BL/6J APOE LIVER apoptosis

Gypenoside ameliorates insulin resistance and hyperglycemia via the AMPK-mediated signaling pathways in the liver of type 2 diabetes mellitus mice被引量：3: 《Food Science and Human Wellness》2022年第5期1347-1354,共8页Mengxue Song Dehong Tan Bin Li Yanqun Wang Lin Shi; supported by the National Natural Science Foundation of China(81602983)。; Gynostemma pentaphyllum,also called"Southern Ginseng"in China,is a traditional Asian folk medicinal plant.Gypenosides(Gps)are the biologically active constituents of G.pentaphyllum,which have been reported with hypogl...; 关键词：GYPENOSIDES Gynostemma pentaphyllum Diabetes Insulin resistance GLUCONEOGENESIS Adenosine monophosphate-activated protein kinase(AMPK)

Ethanol extract from Gynostemma pentaphyllum ameliorates dopaminergic neuronal cell death in transgenic mice expressing mutant A53T human alpha-synuclein被引量：6: 《Neural Regeneration Research》2020年第2期361-368,共8页Hyun Jin Park Ting Ting Zhao Seung Hwan Kim Chong Kil Lee Bang Yeon Hwang Kyung Eun Lee Myung Koo Lee; supported by the National Research Foundation of Korea,grant No.2016R1D1A3B03930722(to MKL),Republic of Korea; Gynostemma(G.) pentaphyllum(Cucurbitaceae) contains various bioactive gypenosides. Ethanol extract from G. pentaphyllum(GP-EX) has been shown to have ameliorative effects on the death of dopaminergic neurons in animal...; 关键词：A53T Α-SYNUCLEIN genetic mice ERK1/2 GYNOSTEMMA pentaphyllum GYPENOSIDES Parkinson’s disease retention transfer latency time

Effect of light quality on total gypenosides accumulation and related key enzyme gene expression in Gynostemma pentaphyllum被引量：2: 《Chinese Herbal Medicines》2018年第1期34-39,共6页ting wang xiang-rong tian xiao-yu wu zhun luo gui li xiao-lie peng shi-biao liu; financially supported by the National Natural Science Foundation of China (31760044,31260039);Key Course of Hunan Province (Ecology),Jishou University (2015005); Objective： Light quality has effect on the accumulation of gypenosides in the medicinal plant Gynosternma pentaphyllum in the family Cucurbitaceae, while the squalene synthase （SS） and squalene epoxidase （SE） are...; 关键词：gene expression Gynostemma pentaphyllum GYPENOSIDES light quality squalene epoxidase squalene synthase

Neuroprotective effects of gypenosides in experimental autoimmune optic neuritis被引量：3: 《International Journal of Ophthalmology(English edition)》2017年第4期541-549,共9页Hong-Kan Zhang Yuan Ye Zhen-Ni Zhao Kai-Jun Li Yi Du Qiu-Ming Hu Jian-Feng He; Supported by the National Natural Science Foundation of China(No.81260149;No.81360152;No.81560162); AIM：To determine whether gypenosides have protective effects in experimental autoimmune optic neuritis（EAON）.METHODS：Mice were randomly divided into seven groups：control group,model group,three different density ...; 关键词：GYPENOSIDES experimental autoimmune optic neuritis visual evoked potential optical coherence tomography histopathology

绞股蓝皂苷对2型糖尿病合并非酒精性脂肪性肝病大鼠葡萄糖和脂质代谢的影响被引量：5: 《世界中西医结合杂志》2017年第3期337-341,352,共6页贺琴李刚李芳李金科雷旭雷飞飞李儒贵谭华炳; 2009-2010年湖北省卫生厅科研项目计划(JX4B58); 目的研究绞股蓝皂苷(gypenosides,GPS)对2型糖尿病并非酒精性脂肪性肝病(type2 diabetes mellitus and nonalcoholic fatty liver disease,T2DM-NAFLD)大鼠糖和血脂代谢的影响。方法60只SD大鼠被分为正常对照组(Ⅰ组,n=8)和T2DM-NAFLD...; 关键词：绞股蓝皂苷(gypenosides GPS) 2型糖尿病非酒精性脂肪性肝病(type 2 DIABETESMELLITUS and NONALCOHOLIC FATTY liver disease T2DM-NAFLD) 血糖(BS) 甘油三酯(TG)

Mechanism of action of gypenosides on type 2 diabetes and non-alcoholic fatty liver disease in rats被引量：24: 《World Journal of Gastroenterology》2015年第7期2058-2066,共9页Qin He Jin-Ke Li Fang Li Ru-Gui Li Guo-Qing Zhan Gang Li Wei-Xing Du Hua-Bing Tan; Supported by Bureau of Public Health of Hubei Province; AIM:To explore the mechanism of action of gypenosides(GPs)on type 2 diabetes mellitus and non-alcoholic fatty liver disease(T2DM-NAFLD)in rats.METHODS:Sixty rats were randomly divided into a healthy group,an untreated...; 关键词：GYPENOSIDES TYPE 2 DIABETES MELLITUS Non-alcoholic

Evaluating effects of gypenosides and soyasaponins on differentiation of neural stem cells as an in vitro model被引量：4: 《Journal of Shanghai University(English Edition)》2008年第1期91-94,共4页吴婕文铁桥; Project supported by the National Basic Research Program of China （Grant No.2006CB500702）, the National Natural Science Foundation of China （Grant No.30570590）, and the Science Foundation of Shanghai Municipal Commission of Science and Technology （Grant No.03JC14030）; Neural stem cell has a potential to differentiate into neurons, astrocytes and oligodendrocytes. It provides an in vitro model to screen herbal medicines on the cellular differentiation and development level. In this ...; 关键词：neural stem cell GYPENOSIDES SOYASAPONINS herbal medicine in vitro model

绞股蓝防治缺血性脑卒中的药理研究概述: 《广西中医药》2005年第1期8-9,共2页池明宇梅学文郑贵元; 关键词：绞股蓝总皂苷(Gypenosides GPs) 缺血性脑卒中脑保护药理作用综述

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