CYCLOHEXIMIDE

作品数:16被引量:34H指数:4
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相关领域:医药卫生更多>>
相关作者:韩东姜微波廖劲晖宋建国丁子敬更多>>
相关机构:山东农业大学中国农业大学中国科学院第二军医大学更多>>
相关期刊:《Horticultural Plant Journal》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Science Bulletin》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Cycloheximide promotes type I collagen maturation mainly via collagen prolyl 4-hydroxylase subunitα2
《Acta Biochimica et Biophysica Sinica》2022年第12期1832-1840,共9页Run Shi Miao Xu Huazhe Ye Shanshan Gao Jingfeng Li Huan Li Chaoyang Li 
supported by grants from the National Natural Science Foundation of China(Nos.32070147 and 30670170 to C.L.);the Guangzhou Key Medical Discipline Construction Project.
Aberrant deposition of collagen is associated with cancer development and tissue fibrosis.Proline hydroxylation,catalyzed by collagen prolyl 4-hydroxylases(C-P4Hs),is necessary for collagen maturation and secretion.He...
关键词:CYCLOHEXIMIDE type I collagen collagen prolyl 4-hydroxylases proline hydroxylation 
白刺链霉菌(Streptomyces albospinus)CT205产环己酰亚胺含量测定方法的建立
《微生物学杂志》2020年第6期96-101,共6页王小姣 李梦雅 王世梅 
国家自然科学基金项目(41671256);国家重点研发计划项目(2018YFD0500201)。
建立白刺链霉菌(Streptomyces albospinus)CT205代谢产环己酰亚胺含量的检测方法,为菌株CT205的开发利用提供技术支持。采用高效液相色谱法(HPLC)、生物活性法和分光光度法等三种检测手段分别测定菌株CT205发酵上清液及粗提物中活性物...
关键词:白刺链霉菌(Streptomyces albospinus)CT205 环己酰亚胺(Cycloheximide) 高效液相色谱法 生物活性法 分光光度法 
Isolation of Secondary Metabolites with Antimicrobial Activities from Bacillus amyloliquefaciens LWYZ003被引量:3
《Transactions of Tianjin University》2019年第1期38-44,共7页Zhen Liu Yiting Wang Xiaoqiang Jia Wenyu Lu 
supported by the National Basic Research Program of China ("973" Program) (no. 2012CB721105);the Major Research Plan of Tianjin, China (no. 16YFXTSF00460)
The strain LWYZ003, which can restrain multiple pathogens, was screened from the sediment of the ocean and identified as Bacillus amyloliquefaciens. Large-scale fermentation and modern chromatographic separation techn...
关键词:CYCLOHEXIMIDE TREHALOSE BACILLUS amyloliquefaciens Bioactivity-guided ISOLATION Antibiotic 
Protective effect and its mechanism of codonopsis pilosula polysaccharide on memory consolidation disorder induced by cycloheximide in mice
《中国药理学与毒理学杂志》2017年第10期992-992,共1页Wei LI Wei-da LIU Li-yao DUAN Jiang-man LI Dan-shen ZHANG 
supported by National Natural Science Foundation(81202192);Fund of Hebei Provincial Health Bureau(20130037)
OBJECTIVE To investigate the protective effect of Codonopsis Pilosula Polysaccharide(CPPS)on improving of the memory consolidation disorder induced by Cycloheximide and its possible mechanisms in mice.METHODS The mice...
关键词:codonopsis pilosula polysaccharide CYCLOHEXIMIDE memory consolidation disorder Morris water maze CaMKⅡ/CREB signaling pathways 
Himalomycin A and cycloheximide-producing marine actinomycete from Lagos Lagoon soil sediment
《Journal of Coastal Life Medicine》2015年第5期361-365,共5页Davies Olabisi Flora Adeleye Isaac Adeyemi Wang Peng George 
Objective:To isolate and screen Actinomycetes from Lagos Lagoon soil sediments for antibiotic production.Methods:Soil samples were collected from four different locations of Lagos Lagoon and were dried for 2 weeks.Act...
关键词:Marine ACTINOMYCETES STREPTOMYCES Himalomycin A CYCLOHEXIMIDE Molecular identification Morphological characteristics Gaschromatography-mass SPECTROMETER 
The Effects of Polyphenol Oxidase and Cycloheximide on the Early Stage of Browning in Phalaenopsis Explants被引量:5
《Horticultural Plant Journal》2015年第3期172-180,共9页XU Chuanjun RU Zhiwei LI Ling ZENG Biyu HUANG Junmei HUANG Wen HU Ou 
supported by Natural Science Foundation in China(31070618)
Explant browning is one of the major problems in the tissue culture process, and polyphenol oxidase(PPO), is the major proteases involved in plant tissue browning. We investigated the effects of polyphenol oxidase on ...
关键词:PHALAENOPSIS PPO explant browning CHX gene expression 
Application and interpretation of current autophagy inhibitors and activators被引量:13
《Acta Pharmacologica Sinica》2013年第5期625-635,共11页Ya-ping YANG Li-fang HU Hui-fen ZHENG Cheng-jie MAO Wei-dong HU Kang-ping XIONG Fen WANG Chun-feng LIU 
Acknowledgements This work was supported by the National Natural Science Foundation of China (No 81171213), the Natural Science Foundation of Jiangsu Province of China (No BK2010228), the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (No 10KJB320016) and Plans for Gradu- ate Research and Innovation in Colleges and Universities of Jiangsu Province (No CX10B-0492).
is the major intracellular degradation system, by which cytoplasmic materials are delivered to and degraded in the lyso- some. As a quality control mechanism for cytoplasmic proteins and organelles, autophagy plays im...
关键词:AUTOPHAGY cancer neurodegenerative diseases PI3K inhibitor CYCLOHEXIMIDE lysosomal lumen alkalizer Rack1 protein ERstress inducer rapamycin LiCl 
Characterization of macrophage mutants established by their resistance to LPS and cycloheximide-induced apopotic cell death
《Advances in Bioscience and Biotechnology》2012年第6期770-781,共12页Fumio Amano Shoko Tsukabe Reiko Teshima Keiko Waku Kiyoko Kohama 
Macrophages are activated by bacterial lipopolysaccharide (LPS) to produce inflammatory cytokines such as TNF-α or reactive oxygen species such as nitric oxide or superoxide anion. However, in the presence of an inhi...
关键词:MACROPHAGE J774.1 Cell Line LPS Apoptosis CD14 
Protective Effects of Focal Ischemic Preconditioning and HSP70 Expression on Middle Cerebral Artery Occlusion in Rats
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2006年第4期436-439,共4页赵建华 孙圣刚 陈小武 
Summary: To systematically evaluate the importance of protein synthesis in ischemic preconditioning (PC)-induced ischemic tolerance (IT), temporary middle cerebral artery occlusion (MCAO) by Longa (20 min) wa...
关键词:ischemic precondioning ischemic tolerance brain infarct HSP70 CYCLOHEXIMIDE 
Cycloheximide prevents production of arresting,a fraction of 30-50 kDa obtained from seminiferous tubule conditioned medium
《Asian Journal of Andrology》2004年第4期359-364,共6页Gustavo F.Gonzales Stella Hartinger Yetssy Flores Kelly Zárate Pedro Yi 
Aim: To evaluate the effect of a protein synthesis inhibitor cycloheximide on arresting activity in spermato-genesis and sperm count in male rats. Methods: The study used seminiferous tubule (ST) segments from adult r...
关键词:CYCLOHEXIMIDE ARRESTING conditioned medium seminiferous tubule sperm production TRANSILLUMINATION 
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