CLONAL

作品数：139被引量：228H指数：7
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相关作者：董鸣蒋高明于飞海沈景林丁雪梅更多>>
相关机构：中国科学院植物研究所吉林大学沈阳师范大学中国科学院更多>>
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Differential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword
《Neural Regeneration Research》2025年第8期2395-2407,共13页María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo Diana Simón Johnny Di Pierdomenico Alejandro Gallego-Ortega Mar Pérez JoséMCabrera-Maqueda Javier Sierra Manuel Vidal-Sanz María Teresa Moreno-Flores Marta Agudo-Barriuso 
supported by the Spanish Ministry of Economy and Competitiveness,No.PID2019-106498GB-I00(to MVS);the Instituto de Salud CarlosⅢ,Fondo Europeo de Desarrollo Regional“Una manera de hacer Europa”,No.PI19/00071(to MAB);Ministerio de Ciencia e Innovación Project,No.SAF2017-82736-C2-1-R(to MTMF)in Universidad Autónoma de Madrid;Fundación Universidad Francisco de Vitoria(to JS)。
Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic nerve.Still,it is unknown whether olfactory enshea...
关键词：cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells 
The link between ten-eleven translocation-2(Tet2)related clonal hematopoiesis and sequential onset of two hematologic malignancies
《Genes & Diseases》2025年第1期14-18,共5页Jin Huang Haolong Lin Xia Mao Min Xiao Xiaoxi Zhou Qilin Ao Liang Huang 
supported by funding from the National Natural Science Foundation of China(No.82070211 to Liang Huang,No.82170167 to Xiaoxi Zhou,No.81800356 to Jin Huang);the National Key R&D Program of China(No.2022YFC2502604 to Liang Huang).
of somatic mutations of genes known to be recurrently mutated in hematologic malignancies in the peripheral blood of healthy individuals.1 When clonal hematopoiesis is associated with a mutation at a variant allele fr...
关键词：MALIGNANCIES HEMATOPOIESIS ALLELE 
Association Between Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Patients With Acute Coronary Syndrome Who Have Quit Smoking:Study Design of a Prospective Cohort Study
《Cardiology Discovery》2024年第4期280-283,共4页Jing Li Zizhao Qi Ying Xu Yinan Cao Yi Li Yaling Han 
funded by Liaoning Provincial Science and Technology Project(2022-MS-045).
Despite quitting smoking,patients with acute coronary syndrome(ACS)still have an increased risk of cardiovascular events.Clonal hematopoiesis of indeterminate potential(CHIP),which may be induced by smoking,has been i...
关键词：Acute coronary syndrome Clonal hematopoiesis of indeterminate potential SMOKING Cardiovascular events 
Can dental problems be indicative of clonal hematopoiesis?
《Cell Research》2024年第12期824-825,共2页Soichi Sano Kenneth Walsh 
A new study published in Cell provides evidence that clonal hematopoiesis of indeterminate potential(CHIP)can promote bone loss in periodontal disease and rheumatoid arthritis through pro-inflammatory mechanisms.
关键词：mechanisms. HEMATOPOIESIS CLONAL 
Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells
《Cellular & Molecular Immunology》2024年第12期1459-1473,共15页Anna Nogalska Jiya Eerdeng Samir Akre Mary Vergel-Rodriguez Yeachan Lee Charles Bramlett Adnan Y.Chowdhury Bowen Wang Colin G.Cess Stacey D.Finley Rong Lu 
supported by NIH-R00-HL113104,R01HL138225,and R35HL150826;R.Lu is a scholar of the Leukemia&Lymphoma Society(LLS-1370-20);The project described was supported in part by award number P30CA014089 from the National Cancer Institute;CB is supported by National Institutes of Health grant 1F31HL149278-01A1;JE is supported by the California Institute for Regenerative Medicine grant EDUC4-12756.
The age-associated decline in immunity manifests as imbalanced adaptive and innate immune cells,which originate from the aging of the stem cells that sustain their regeneration.Aging variation across individuals is we...
关键词：aging clonal tracking hematopoietic stem cells lineage bias MYELOPOIESIS 
Epidemiology and Clonal Spread Evidence of Carbapenem-Resistant Organisms in the Center of Care and Protection of Orphaned Children, Vietnam
《Open Journal of Medical Microbiology》2024年第3期165-189,共25页Van Kim Nguyen Pirom Noisumdaeng Pol. Maj. Katiya Ivanovitch Stephen Baker Eugene Athan Stephanie Jones Le Thi Lan Larry Croft Yin Peng Lee Tara Cassidy Van Hung Tran Thi Hang Phan Huu Tinh Ho 
Objective: To determine the prevalence of colonization and transmission of carbapenem-resistant Gram-negative organisms in order to develop of an effective infection prevention program. Design: Cross-sectional study w...
关键词：Carbapenem-Resistant Organisms Contamination Hand Hygiene Whole Genome Sequencing Infection Prevention 
Belowground Bud Bank Is Insensitive to Short-Term Nutrient Addition in the Meadow Steppe of Inner Mongolia
《Phyton-International Journal of Experimental Botany》2024年第6期1129-1141,共13页Jin Tao Jiatai Tian Dongmei Li Jinlei Zhu Qun Ma Zhiming Zhang Jungang Chen Yipeng Liu Jianqiang Qian 
support from the National Natural Science Foundation of China(41877542).
Human activities and industrialization have significantly increased soil nutrients,such as nitrogen(N)and phos-phorus(P),profoundly impacting the composition and structure of plant community,as well as the ecosystem fu...
关键词：Clonal trait population regeneration community dynamics soil resource availability nitrogen addition 
Reproductive height determines the loss of clonal grasses with nitrogen enrichment in a temperate grassland
《Plant Diversity》2024年第2期256-264,共9页Xu Chen Haining Lu Zhengru Ren Yuqiu Zhang Ruoxuan Liu Yunhai Zhang Xingguo Han 
supported by a grant from the National Natural Science Foundation of China(grant no.32071603 and 32122055);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA26020101)。
Tall clonal grasses commonly display competitive advantages with nitrogen(N)enrichment.However,it is currently unknown whether the height is derived from the vegetative or reproductive module.Moreover,it is unclear wh...
关键词：ANPP Biodiversity Clonal grass COLONIZATION EXTINCTION Nitrogen addition frequency 
Epidemiology and genetic characterization of tet(X4)-positive Klebsiella pneumoniae and Klebsiella quasipneumoniae isolated from raw meat in Chengdu City, China
《Biosafety and Health》2024年第2期116-124,共9页Weishuai Zhai Yiqing Wang Honghu Sun Bo Fu Qidi Zhang Congming Wu Jianzhong Shen Dejun Liu Yang Wang 
supported by the National Key Research and Development Program of China(No.2022YFD1800400);National Natural Science Foundation of China(No.81991531);Natural Science Foundation of Shandong Province(No.ZR2020MC188);The sequence data of 25 K.pneumoniae isolates have been submitted to NCBI under BioProject accession number PRJNA1011004.
The rapid spread of mobile tigecycline resistance presents a significant public health threat,particularly with the increasing prevalence of tet(X4)-positive Enterobacterales across various species.This study aimed to...
关键词：tet(X4) TIGECYCLINE K.pneumoniae Clonal spread Horizontal transfer 
Genome and clonal hematopoiesis stability contrasts with immune,cfDNA,mitochondrial,and telomere length changes during short duration spaceflight
《Precision Clinical Medicine》2024年第1期1-13,共13页J.Sebastian Garcia-Medina Karolina Sienkiewicz S.Anand Narayanan Eliah G.Overbey Kirill Grigorev Krista A.Ryon Marissa Burke Jacqueline Proszynski Braden Tierney Caleb M.Schmidt Nuria Mencia-Trinchant Remi Klotz Veronica Ortiz Jonathan Foox Christopher Chin Deena Najjar Irina Matei Irenaeus Chan Carlos Cruchaga Ashley Kleinman JangKeun Kim Alexander Lucaci Conor Loy Omary Mzava Iwijn De Vlaminck Anvita Singaraju Lynn E.Taylor Julian C.Schmidt Michael A.Schmidt Kelly Blease Juan Moreno Andrew Boddicker Junhua Zhao Bryan Lajoie Andrew Altomare Semyon Kruglyak Shawn Levy Min Yu Duane C.Hassane Susan M.Bailey Kelly Bolton Jaime Mateus Christopher E.Mason 
supported by the Leukemia and Lymphoma Society (Grants No.LLS 9238-16 and MCL7001-18);the National Institutes of Health (Grants No.P01CA214274,R01CA249054 and R01MH117406);the WorldQuant Foundation,NASA (Grants No.80NSSC19K0432,80NSSC22K0254,NNH18ZTT001N-FG2,NNX13AE45G,NNX14AH50G,NNX17AB26G).
Background The Inspiration4(I4)mission,the first all-civilian orbital flight mission,investigated the physiological effects of short-duration spaceflight through a multi-omic approach.Despite advances,there remains mu...
关键词：genomes CLONAL HEMATOPOIESIS STABILITY IMMUNE mitochondria RIBOSOMES SPACEFLIGHT 
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